Special Issues

Viruses publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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H5N1 Influenza Viruses
edited by
submission deadline 31 Dec 2025 | 6 articles | Viewed by 6675 | Submission Open
Keywords: H5N1; avian influenza; genetic diversity; immune response; vaccines and antiviral therapies
(This special issue belongs to the Section Animal Viruses)
Molecular Biomarkers for Viral Infection submission deadline 31 Dec 2025 | 3 articles | Viewed by 5078 | Submission Open
Keywords: molecular biomarkers; viral infections
(This special issue belongs to the Section Animal Viruses)
Preparation for the Next Potential Pandemic—Chikungunya, Dengue, Zika and Other Viruses
edited by
submission deadline 31 Dec 2025 | 4 articles | Viewed by 5052 | Submission Open
Keywords: chikungunya; dengue; zika; next pandemic; epidemiology; pharmaceutics; immunology
(This special issue belongs to the Section Human Virology and Viral Diseases)
Application of Genetically Engineered Plant Viruses
edited by
submission deadline 31 Dec 2025 | 3 articles | Viewed by 4437 | Submission Open
Keywords: plant virus; infectious clone; viral vector; virus-induced gene silencing (VIGS); virus-like particles (VLPs); cross-protection
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
EBV and Disease: New Perspectives in the Post COVID-19 Era
edited by and Dengke Li
submission deadline 31 Dec 2025 | 5 articles | Viewed by 4409 | Submission Open
Keywords: EBV; reactivation and immune dysregulation; EBV-associated malignancies; autoimmune diseases; diagnostic and therapeutic
(This special issue belongs to the Section Human Virology and Viral Diseases)
Molecular Virus-Insect Interactions, 2nd Edition
edited by Li-Long Pan
submission deadline 31 Dec 2025 | 3 articles | Viewed by 3375 | Submission Open
Keywords: plant virus-insect vector interactions; virus transmission; entomopathogenic virus-insect host interactions; insect-specific viruses; induction and suppression of immune responses
(This special issue belongs to the Section Invertebrate Viruses)
Intra-patient Viral Evolution and Diversity
edited by Adam A. Capoferri and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 3103 | Submission Open
Keywords: intra-patient viral evolution; drug resistance; immune escape; co-evolution; virus persistence; virus evolution
(This special issue belongs to the Section Human Virology and Viral Diseases)
Surveillance, Transmission Dynamics, and Control of Zoonotic Viruses
edited by Dimitrios A. Chatzidimitriou, and Ilias Bouzalas
submission deadline 31 Dec 2025 | 2 articles | Viewed by 2697 | Submission Open
Keywords: zoonosis; surveillance; epidemiology; diagnostics
(This special issue belongs to the Section Animal Viruses)
Human Hepatitis Viruses and Their Animal Homologues
edited by and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 2227 | Submission Open
Keywords: hepatitis viruses; animal virome; genetic diversity; genomic organization; ecology and evolution; molecular biology; molecular epidemiology; zoonotic potential
(This special issue belongs to the Section General Virology)
Coronavirus Pathogenesis and Virus-Host Interaction
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1688 | Submission Open
Keywords: COVID-19; SARS-CoV-2; SARS-CoV-1; MERS-CoV; pathogenesis; virus– host interaction; virus entry; host factors; animal models; SARS-CoV-2 variants
(This special issue belongs to the Section General Virology)
Emerging Microbes, Infections and Spillovers, 2nd Edition submission deadline 31 Dec 2025 | 2 articles | Viewed by 1343 | Submission Open
Keywords: emerging infections; virus spillovers; microbes; cross-species transmission; virus evolution; viral disease; virus reservoirs; virus– host interaction; pathogenesis
(This special issue belongs to the Section Animal Viruses)
Porcine Viruses 2025
edited by , and
submission deadline 31 Dec 2025 | 3 articles | Viewed by 1313 | Submission Open
Keywords: epidemiology; pathogenesis; immune evasion; virus evolution; vaccine
(This special issue belongs to the Section Animal Viruses)
SARS-CoV-2, COVID-19 Pathologies, Long COVID, and Anti-COVID Vaccines
edited by
submission deadline 31 Dec 2025 | Viewed by 1189 | Submission Open
Keywords: SARS-CoV-2; COVID-19; long COVID; anti-COVID vaccines; spikeopathy; renin– angiotensin system
(This special issue belongs to the Section Coronaviruses)
Antiviral Development for Emerging and Re-Emerging Viruses
edited by and
submission deadline 31 Dec 2025 | 2 articles | Viewed by 1155 | Submission Open
Keywords: protein– protein interaction; viral– host interaction; viral replication; antiviral; human viruses; emerging infections
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Severe Fever with Thrombocytopenia Syndrome Virus 2025
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1140 | Submission Open
Keywords: SFTS; SFTSV; emerging viral infections
(This special issue belongs to the Section Human Virology and Viral Diseases)
Harnessing AI and Machine Learning for Antiviral Development
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1133 | Submission Open
Keywords: artificial intelligence; machine learning; antiviral therapies; personalized medicine; drug discovery; drug repurposing; drug resistance
(This special issue belongs to the Section General Virology)
Virology and Immunology of Gene Therapy 2025
edited by Weidong Xiao and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 716 | Submission Open
Keywords: gene therapy; viral vector; vaccine; immune responses; viruses; AAV; lentiviral vectors; neutralizing antibody
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Advancing Hepatitis Elimination: HBV, HDV, and HCV
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 708 | Submission Open
Keywords: hepatitis elimination; HBV; HCV; HDV
(This special issue belongs to the Section Human Virology and Viral Diseases)
Arboviruses and Climate, 2nd Edition
edited by José Lourenço and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 633 | Submission Open
Keywords: arbovirus; climate; climate change; arthropods; vectors; epidemiology; evolution; ecology; public health
(This special issue belongs to the Section Invertebrate Viruses)
Viral Strategies and Cellular Countermeasures That Regulate mRNA Access to the Translation Apparatus: 2nd Edition
edited by
submission deadline 31 Dec 2025 | Viewed by 613 | Submission Open
Keywords: virus– host interactions; IRES elements; RNA structure; translation initiation; translational control; innate immune response; RNA modification
(This special issue belongs to the Section General Virology)
Virological and Immunological Factors Underlying HBV Functional Cure and HBV Reactivation
edited by
submission deadline 31 Dec 2025 | Viewed by 585 | Submission Open
Keywords: HBV persistence; HBV functional cure; cccDNA; immunology of HBV; HBV reactivation; immune-escape mutations
(This special issue belongs to the Section Human Virology and Viral Diseases)
Current: Measles Outbreak, a Global Situation
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 555 | Submission Open
Keywords: measles; vaccination; surveillance; complications; outbreaks
(This special issue belongs to the Section Human Virology and Viral Diseases)
Zika Virus and Congenital Zika Syndrome, 2nd Edition
edited by Marcos Vinicius da Silva Pone and Sheila Moura Pone
submission deadline 31 Dec 2025 | 1 articles | Viewed by 533 | Submission Open
Keywords: viral infections; Zika virus; congenital Zika syndrome
(This special issue belongs to the Section Human Virology and Viral Diseases)
The Structure and Function of Flavivirus Genes and Proteins
edited by and Kay Choi
submission deadline 31 Dec 2025 | 1 articles | Viewed by 343 | Submission Open
Keywords: flavivirus; structural protein; non-structural protein; 5'UTR; 3'UTR
(This special issue belongs to the Section General Virology)
Advancing Research of Anelloviruses, Second Edition submission deadline 31 Dec 2025 | Viewed by 342 | Submission Open
Keywords: TTV; TTMV; TTMDV; virome; viral species; immune system; orphan virus
(This special issue belongs to the Section Human Virology and Viral Diseases)
Lung Immunity to Viral Infections submission deadline 31 Dec 2025 | Viewed by 312 | Submission Open
Keywords: respiratory virus; lung immune response; vaccines to respiratory virus; microbiota and lung immune response; environmental factors and lung immune responses; virus– host interaction in the lung; immunotherapies to prevent or treat respiratory viral infection
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Phage Display in Cancer Diagnosis and Screening
edited by
submission deadline 31 Dec 2025 | Viewed by 301 | Submission Open
Keywords: phage display; cancer; diagnosis; screening; prognosis and monitoring
(This special issue belongs to the Section Bacterial Viruses)
Virus Biosensing
edited by Guobin Mao
submission deadline 31 Dec 2025 | Viewed by 293 | Submission Open
Keywords: virus detection; molecular diagnosis; immunoassay; nucleic acid amplification; CRISPR-based detection; nucleic acid assembly; biosensor; point-of-care testing
(This special issue belongs to the Section General Virology)
RNA Viruses Replication and Innate Immunity
edited by
submission deadline 31 Dec 2025 | Viewed by 277 | Submission Open
Keywords: RNA virus replication and transcription; pathogen-associated molecular patterns; interferons; cytokines; signaling pathways
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Virus Bioinformatics 2025
edited by and Paula Istvan
submission deadline 31 Dec 2025 | Viewed by 241 | Submission Open
Keywords: virus bioinformatics; software; viral metagenomics and ecology; virus– host interactions; viral diversity and evolution; virus identification
(This special issue belongs to the Section General Virology)
Tackling Viral Resistance—Advances in Mechanisms, Detection, and Control
edited by and Claudia Palladino
submission deadline 31 Dec 2025 | Viewed by 230 | Submission Open
Keywords: viral resistance; antiviral therapies; drug resistance mechanisms; epidemiology; diagnostic advancements; clinical management
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Viral Immunology in Transplant Patients submission deadline 31 Dec 2025 | Viewed by 203 | Submission Open
Keywords: viral infections; transplant patients; immunocompromised; immune response; host– pathogen interactions; immunotherapies; diagnostic approaches; preventive strategies
(This special issue belongs to the Section Human Virology and Viral Diseases)
Modeling Zoonotic and Vector-Borne Viruses in Evolving Ecological Systems
edited by , Sani Isah Abba and Ismail Abdulrashid
submission deadline 31 Dec 2025 | Viewed by 185 | Submission Open
Keywords: zoonotic viruses; vector-borne diseases; climate change and disease dynamics; epidemiological modeling; outbreak forecasting and control; human behavior; virus– host– vector interactions
(This special issue belongs to the Section Animal Viruses)
Experimental Animal and Organoid-Based Lethal Virus Infection Models for Human, Companion Animals and Livestock
edited by
submission deadline 31 Dec 2025 | Viewed by 183 | Submission Open
Keywords: organoid models; experimental animals; lethal virus infections; pathogenesis; vaccine development; therapeutic drugs; in vitro models; in vivo models; human viral infections; companion animal viral infections; livestock viral infections; viral infection models; ferret; hamster; transgenic mouse
(This special issue belongs to the Section General Virology)
Oncogenic Infections and Cancer: Clinical Insights and Emerging Therapeutics
edited by G. Hossein Ashrafi and Mustafa Ozdogan
submission deadline 31 Dec 2025 | Viewed by 148 | Submission Open
Keywords: oncogenesis; viral oncology; bacterial oncogenesis; human papillomavirus (HPV); Epstein– Barr virus (EBV); Kaposi’ s sarcoma-associated herpesvirus (KSHV); hepatitis B virus (HBV); hepatitis C virus (HCV); human T-lymphotropic virus (HTLV-1); Helicobacter pylori; infection-driven cancers; molecular mechanisms; tumor microenvironment; immunotherapy; viral persistence; antiviral therapies; CRISPR-based treatments; cancer prevention; vaccine development; immune checkpoint inhibitors; diagnostic biomarkers; personalized medicine; translational oncology; therapeutic resistance; emerging therapeutics
(This special issue belongs to the Section Human Virology and Viral Diseases)
Picornavirus Evolution, Host Adaptation and Antiviral Strategies
edited by
submission deadline 31 Dec 2025 | Viewed by 145 | Submission Open
Keywords: virus evolution; new picornavirus; variant picornavirus; host adaptation; vaccine immunization; antiviral drugs
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Virus Infection Fate Regulation
edited by Andreas Meyerhans and
submission deadline 31 Dec 2025 | Viewed by 129 | Submission Open
Keywords: virus infection fate; dynamics; immune response; cellular response; regulation
(This special issue belongs to the Section General Virology)
Spotlight on Bocavirus and Other Parvoviruses, and Overlooked Respiratory Viruses submission deadline 31 Dec 2025 | Viewed by 92 | Submission Open
Keywords: bocavirus; Parvovirus B19; canine parvovirus; porcine parvovirus; metapneumovirus; rhinovirus Planned Papers 1. Molecular detection of Porcine cytomegalovirus (PCMV) and Porcine parvovirus (PPV) in domestic pigs and wild boars from Croatia 2.  Protoparvovirus carnivoran 1 outbreak in golden jackals in Croatia 3.  Epidemiology of parvovirus B19 in Croatian childbearing-aged women: A ten-year seroprevalence study
(This special issue belongs to the Section Animal Viruses)
Antigenic Drift in Respiratory Viruses
edited by
submission deadline 31 Dec 2025 | Viewed by 67 | Submission Open
Keywords: respiratory viruses; virus diversity; viral recombination; reassortment; zoonotic viruses; wastewater pathogen surveillance; viral sequencing; virus evolutionary characterization; animal viruses
(This special issue belongs to the Section Human Virology and Viral Diseases)
Interferon-Stimulated Genes in Antiviral Immunity
edited by
submission deadline 31 Dec 2025 | Viewed by 65 | Submission Open
Keywords: interferon-stimulated genes; ISGs; non-coding RNA; viral replication; deep learning tools
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Innovative Drug Discovery for Emerging Viral Diseases, 2nd Edition
edited by Chaoping Chen
submission deadline 31 Dec 2025 | Viewed by 65 | Submission Open
Keywords: antivirals; drug discovery; high-throughput screen; SARS-CoV-2; influenza virus; RSV; zika; ebola virus; chikungunya virus; emerging/re-emerging RNA viral pathogens; host-directed therapies; immunomodulator
(This special issue belongs to the Section General Virology)
Animal Virus Discovery and Genetic Diversity: 2nd Edition
edited by
submission deadline 31 Dec 2025 | Viewed by 52 | Submission Open
Keywords: animal virus; evolution; genetic; diversity; richness; emerging viruses; virome; metagenomics; ecology; cross-species transmission; zoonotic
(This special issue belongs to the Section Animal Viruses)
Mechanisms of Ribozyviria Transmission in Animal and Vegetal Holobionts
edited by and Ferruccio Bonino
submission deadline 31 Dec 2025 | Viewed by 21 | Submission Open
Keywords: viroid-like RNAs; holobionts; RNA viruses; circular RNA genomes; satellite viruses; HBsAg (hepatitis b surface antigen)
(This special issue belongs to the Section General Virology)
Progress and Prospects in Oncolytic Virotherapy 2025 submission deadline 15 Jan 2026 | Viewed by 160 | Submission Open
Keywords: oncovirotherapy; chemotherapy; preclinical studies; clinical trials; combinatory strategy; safety profile; therapeutic efficacy; immunotherapy
(This special issue belongs to the Section Human Virology and Viral Diseases)
Phage–Antibiotic Combination Therapy
edited by
submission deadline 20 Jan 2026 | Viewed by 537 | Submission Open
Keywords: bacteriophage; antibiotics; phage therapy; phage– antibiotic synergy; combination therapy; in vitro study; sub-lethal dose; emerging alternative; bacteria-killing
(This special issue belongs to the Section Bacterial Viruses)
Viral Infections in Hematopoietic Stem Cell Transplant and Cellular Therapy Recipients, 2nd Edition
edited by Sanjeet Singh Dadwal
submission deadline 30 Jan 2026 | Viewed by 31 | Submission Open
Keywords: HSCT; GVHD; HHV6; CMV; adenovirus; BK and JC virus (polyomaviruses); HIV
(This special issue belongs to the Section Human Virology and Viral Diseases)
Phage Cocktails: Promising Approaches Against Infections
edited by Jin Woo Jun
submission deadline 31 Jan 2026 | 3 articles | Viewed by 5387 | Submission Open
Keywords: phage cocktail; phage therapy; prophylaxis; infectious diseases; veterinary medicine; agriculture; food industry; zoonoses
(This special issue belongs to the Section Bacterial Viruses)
Plant Virus Spillovers
edited by and
submission deadline 31 Jan 2026 | 3 articles | Viewed by 4937 | Submission Open
Keywords: spillover; emergence; replication; wild-plant virus; transmission; virus-cell interaction; vector
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Tick-Borne Viruses: Transmission and Surveillance, 2nd Edition
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 3406 | Submission Open
Keywords: tick-borne viruses; transmissibility; vector competence; virulence; interactions; surveillance; discovery; replication; pathogenesis; vaccine development
(This special issue belongs to the Section Invertebrate Viruses)
Role of Lectins in Viral Infections and Antiviral Intervention
edited by Yuan Guo
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1514 | Submission Open
Keywords: lectin– glycan interaction; membrane fusion; immune evasion; multivalency; glycan conjugates; lectin constructs; antivirals
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
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