Special Issues

Viruses publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Epigenetic Modifications in Viral Infections, Volume II submission deadline 1 Jul 2025 | 1 articles | Viewed by 598
Keywords: viral pathogenesis; virus– host interaction; epigenetic modifications; acetylation; methylation; proteomics; genomics
(This special issue belongs to the Section General Virology)
Glycans in Virus-Host Interactions
edited by Rahul Raman
submission deadline 15 Jul 2025 | 4 articles | Viewed by 14494 | Submission Open
Keywords: glycoeptiope; glycan receptors; viruses; antibodies; lectins
(This special issue belongs to the Section Animal Viruses)
Unraveling the Pathogenesis of Persistent Virus Infection
edited by and Mie Kobayashi-Ishihara
submission deadline 15 Jul 2025 | 6 articles | Viewed by 12434 | Submission Open
Keywords: pathophysiology; persistent virus infections; chronic diseases; latency; reactivation
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Flow Virometry: A New Tool for Studying Viruses
edited by John Yin
submission deadline 15 Jul 2025 | 5 articles | Viewed by 8966 | Submission Open
Keywords: flow virometry; virus particle detection; virus counting; virus labeling/staining; virus-like particles; scanning ion occlusion sensing
(This special issue belongs to the Section General Virology)
Arboviral Diseases in Livestock submission deadline 15 Jul 2025 | 2 articles | Viewed by 2127 | Submission Open
Keywords: arbovirus; epidemiology; diagnostics; vaccines
(This special issue belongs to the Section Animal Viruses)
Advances in Small-Molecule Viral Inhibitors
edited by Chiara Bertagnin
submission deadline 15 Jul 2025 | 2 articles | Viewed by 444 | Submission Open
Keywords: small-molecule inhibitors; PROTACs; antiviral compounds; drug discovery; protein– protein interaction inhibitors; enzymatic inhibitors
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Spumaretroviruses: Research and Applications
edited by , Marcelo A. Soares, and Martin Löchelt
submission deadline 30 Jul 2025 | Viewed by 638 | Submission Open
Keywords: ancient retroviruses; antivirals; complex retroviruses; endogenous elements; foamy viruses; foamy virus-host interactions; foamy virus prevalence; foamy virus vectors; immune responses; molecular biology and replication; natural infections; nonhuman primates and non-primates; restriction factors spumaretroviruses; structural biology; taxonomy; viral proteins; virus detection assays; zoonoses
(This special issue belongs to the Section Animal Viruses)
COVID-19 Complications and Co-infections
edited by Amir Sohail, and
submission deadline 31 Jul 2025 | 17 articles | Viewed by 27822 | Submission Open
Keywords: SARS-CoV-2; COVID-19; complications; co-infections; hospitalization
(This special issue belongs to the Section Coronaviruses)
Bovine Influenza
edited by Dan Wang and
submission deadline 31 Jul 2025 | 5 articles | Viewed by 16437 | Submission Open
Keywords: cattle; influenza viruses; avian influenza; replication; virulence; transmission; host adaptation; reservoir; epidemiology; one health; vaccine; immune response
(This special issue belongs to the Section Animal Viruses)
Herpesviruses and Associated Diseases
edited by
submission deadline 31 Jul 2025 | 11 articles | Viewed by 13688 | Submission Open
Keywords: human herpesviruses; animal herpesviruses; viral latency and reactivation; immune evasion strategies; herpesvirus– host interactions; herpesvirus biology and pathogenesis; herpesvirus diagnosis; environmental factors; herpesvirus-associated diseases; prevention and treatment strategies; antiviral therapies; vaccine development
(This special issue belongs to the Section Human Virology and Viral Diseases)
Saliva in the Diagnosis of Viral Diseases submission deadline 31 Jul 2025 | 6 articles | Viewed by 11962 | Submission Open
Keywords: saliva; diagnosis; pathogen detection; immunity; biomarkers
(This special issue belongs to the Section Human Virology and Viral Diseases)
The Application of Viruses to Biotechnology 3.0 submission deadline 31 Jul 2025 | 5 articles | Viewed by 11238 | Submission Open
Keywords: viral vectors; plant protection; gene therapy; virus-based vaccines; viral nanotechnology; phage display; viral gene delivery; virus-mediated gene editing; virus-like particles (VLPs)
(This special issue belongs to the Section General Virology)
Evolution and Adaptation of Avian Viruses submission deadline 31 Jul 2025 | 5 articles | Viewed by 8617 | Submission Open
Keywords: virus; poultry; evolution; genetics; diagnosis; host; epidemiology; control; vaccine
(This special issue belongs to the Section Animal Viruses)
Virus Assembly and Genome Packaging submission deadline 31 Jul 2025 | 2 articles | Viewed by 4363 | Submission Open
Keywords: viral assembly; genome packaging; viral structural proteins; host protein; viral– host interactions; antiviral therapies
(This special issue belongs to the Section General Virology)
Novel Strategies to Identify and Eliminate Latent HIV Cells submission deadline 31 Jul 2025 | 1 articles | Viewed by 3218 | Submission Open
Keywords: HIV; HIV-1 infection; antiretroviral therapy (ART); HIV single cell analysis; HIV reservoir; HIV cure  
(This special issue belongs to the Section Human Virology and Viral Diseases)
Virus-Host Protein Interactions
edited by
submission deadline 31 Jul 2025 | 3 articles | Viewed by 3091 | Submission Open
Keywords: protein– protein interactions; antiviral drug discovery; protein target inhibitors
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Viral Resistance submission deadline 31 Jul 2025 | 2 articles | Viewed by 2630 | Submission Open
Keywords: antiviral drugs; resistance; mechanism; mutations; viral escape; viral adaptation; variability; combination therapy
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
HIV Assembly, Release and Maturation
edited by Siddhartha Datta
submission deadline 31 Jul 2025 | 1 articles | Viewed by 2210 | Submission Open
Keywords: HIV assembly and maturation; capsid stability; inositol hexakisphosphate (IP6); genome recognition; endogenous reverse transcription; reorganization; maturation inhibitors; flexibility and dynamics
(This special issue belongs to the Section Human Virology and Viral Diseases)
SARS-CoV-2 Neutralizing Antibodies 3rd Edition
edited by Youchun Wang
submission deadline 31 Jul 2025 | 2 articles | Viewed by 2176 | Submission Open
Keywords: SARS-CoV-2; neutralizing antibodies; neutralization assays; standards; monoclonal antibodies; vaccines; viral variants
(This special issue belongs to the Section Coronaviruses)
An Update on Enterovirus Research, 2nd Edition
edited by
submission deadline 31 Jul 2025 | 2 articles | Viewed by 1582 | Submission Open
Keywords: antivirals; enteroviruses; picornavirus; diagnostics; emerging and re-emerging diseases; viral proteins; virus replication; viral targets; virus– host interactions; vaccine development
(This special issue belongs to the Section Human Virology and Viral Diseases)
Cascade of Care for HIV, Hepatitis and Sexually Transmitted Infections submission deadline 31 Jul 2025 | 2 articles | Viewed by 1017 | Submission Open
Keywords: HIV; AIDS; cascade; linkage; HCV; HBV; sexually transmitted infections
(This special issue belongs to the Section Human Virology and Viral Diseases)
Biosecurity and Plant Viruses: A Call to Action for a Sustainable Future submission deadline 31 Jul 2025 | 1 articles | Viewed by 931 | Submission Open
Keywords: biosecurity; viral disease; sustainable agriculture; emerging plant viruses; quarantine regulations
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Multiple Hosts of SARS-CoV-2, 3rd Edition
edited by and Santhamani Ramasamy
submission deadline 31 Jul 2025 | 1 articles | Viewed by 677 | Submission Open
Keywords: SARS-CoV-2; animal– human interface; animal reservoirs; One Health; pathogenicity and pathogenesis; spillover and spillback; surveillance; virus evolution and adaptation; zoonoses and reverse zoonoses
(This special issue belongs to the Section Coronaviruses)
Viral Diseases of Major Crops
edited by Zaifeng Fan and Yan Shi
submission deadline 31 Jul 2025 | Viewed by 450 | Submission Open
Keywords: viral infection; viral pathogenicity; virus movement; replication; RNA silencing suppressor; host response; host factors; molecular plant– virus– vector interactions
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Maternal to Child Transmission of HIV and the Effects on Pregnancy
edited by Marta López, and
submission deadline 31 Jul 2025 | Viewed by 440 | Submission Open
Keywords: maternal to child transmission; perinatal transmission; pregnancy outcomes; HIV in pregnancy; antiretroviral treatment; preventive strategies; adverse perinatal outcome; prematurity and low birthweight
(This special issue belongs to the Section Human Virology and Viral Diseases)
Synanthropy and Zoonotic Viral Spillover
edited by
submission deadline 31 Jul 2025 | Viewed by 400 | Submission Open
Keywords: zoonoses; synanthropic interactions; virus; emergence; spillover
(This special issue belongs to the Section Animal Viruses)
Human Adenovirus (HAdV) Infection in Children
edited by Adriana Kajon and
submission deadline 31 Jul 2025 | Viewed by 353 | Submission Open
Keywords: epidemiology; pediatric; transplant recipients; antivirals; outbreak; acute respiratory illness; gastroenteritis
(This special issue belongs to the Section Human Virology and Viral Diseases)
Mass Spectrometry and Viral Analysis
edited by Paul D. Gershon
submission deadline 31 Jul 2025 | Viewed by 236 | Submission Open
Keywords: mass spectrometry; viral analysis; mass analysis; virus interaction; dynamics; viral proteins
(This special issue belongs to the Section General Virology)
Simian Immunodeficiency Virus Models of HIV/AIDS in Nonhuman Primates, 2nd Edition
edited by Nina Derby, and
submission deadline 31 Jul 2025 | Viewed by 230 | Submission Open
Keywords: human immunodeficiency virus (HIV); simian immunodeficiency virus (SIV); HIV latency; pathogenesis; cure; vaccination; co-infection; transmission; non-human primate models
(This special issue belongs to the Section Animal Viruses)
Understanding and Control of Rice Viruses
edited by , and
submission deadline 31 Jul 2025 | Viewed by 170 | Submission Open
Keywords: rice viruses; virus detection techniques; virus– host interactions; rice plant resistance to viruses; emerging rice viruses; viral epidemiology; viral diseases management; insect vectors; AI-driven rice virus detection and control
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Role of Bacteriophage in Intestine Microbial Communities
edited by Yi Duan
submission deadline 31 Jul 2025 | Viewed by 127 | Submission Open
Keywords: bacteriophage; intestinal microbiome; virome; microbial homeostasis; phage therapy; gut ecology; intestinal dysbiosis; antimicrobial resistance; microbiome engineering; host– microbe interactions
(This special issue belongs to the Section Bacterial Viruses)
Zoonotic and Vector-Borne Viral Diseases
edited by and Gary Kobinger
submission deadline 1 Aug 2025 | 12 articles | Viewed by 18947 | Submission Open
Keywords: vector-borne viral diseases (VBVDs); vector– host– pathogen interactions; emerging and re-emerging zoonotic diseases; vectors or  reservoirs; vaccine development; and prevention and control measures
(This special issue belongs to the Section Animal Viruses)
Viral Diseases of Domestic Animals
edited by
submission deadline 15 Aug 2025 | 3 articles | Viewed by 2741 | Submission Open
Keywords: viral diseases; emerging infections; domestic animals; epidemiology; pathogenesis
(This special issue belongs to the Section Animal Viruses)
Swine Viruses: Immunology and Vaccinology
edited by and
submission deadline 15 Aug 2025 | Viewed by 302 | Submission Open
Keywords: swine virology; swine immunology; vaccine development; vaccinology; viral pathogenesis; vaccine design; disease prevention; swine health
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Broadly Protective Anti-Viral Vaccines 2025
edited by
submission deadline 29 Aug 2025 | 1 articles | Viewed by 1452 | Submission Open
Keywords: universal vaccines; structure-based rational design; cross-protection; broadly neutralizing antibody; T-cell epitopes; preventative and therapeutic vaccines; adaptive immunology; highly variable virus
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Antiviral Resistance Mutations submission deadline 31 Aug 2025 | 8 articles | Viewed by 14202 | Submission Open
Keywords: antiviral resistance; virus evolution; viral genome mutation; drug-resistant phenotypes; immune escape
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Hepatitis E: Molecular Virology, Pathogenesis, and Treatment, 2nd Edition
edited by
submission deadline 31 Aug 2025 | 7 articles | Viewed by 8309 | Submission Open
Keywords: HEV; HEV life cycle; HEV genotypes; model systems; zoonosis; pathogenesis; HEV– host interations; antivirals
(This special issue belongs to the Section Human Virology and Viral Diseases)
Emerging and Reemerging Plant Viruses in a Changing World submission deadline 31 Aug 2025 | 6 articles | Viewed by 6710 | Submission Open
Keywords: emerging and re-emerging viruses; virus spillover; climate change and global trade; mixed infections; plant– virus– vector relationships
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Aquatic Animal Viruses and Antiviral Immunity
edited by
submission deadline 31 Aug 2025 | 8 articles | Viewed by 6233 | Submission Open
Keywords: aquatic virus; aquatic animals; innate immunity; adaptive immunity; host– virus interactions; fish; aquaculture; biomedical research; aquatic animal stewardship
(This special issue belongs to the Section Animal Viruses)
Viral Infections in Gynecological Diseases
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 3953 | Submission Open
Keywords: herpes viruses; rubella virus; hepatitis viruses; parvovirus B19; HIV; HPV; Zika virus; placenta; gynecology; cancer
(This special issue belongs to the Section Human Virology and Viral Diseases)
Natural, Semisynthetic, and Synthetic Antiviral Drugs Targeting HIV and SARS-CoV-2 submission deadline 31 Aug 2025 | 3 articles | Viewed by 3665 | Submission Open
Keywords: antiviral design and discovery; natural product screening; natural products as a scaffold for semisynthetic antivirals; repurposing drugs; high-throughput screening; antiviral resistance; biophysical characterization of the interaction between antivirals and targets; combination of light and photosensitizers in antiviral discovery; cell-based and in vivo assays; in silico calculations
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Beyond Acute: Navigating Long COVID and Post-Viral Complications
edited by Maggie Bartlett, Janko Nikolich-Žugich, Rubeshan Perumal and Anders Vahlne
submission deadline 31 Aug 2025 | 2 articles | Viewed by 3425 | Submission Open
Keywords: long COVID; post-viral complications; dysregulated immune responses; neurological complications; respiratory complications; cardiovascular complications; pregnancy-related complications
(This special issue belongs to the Section Human Virology and Viral Diseases)
Arboviruses and Global Health: A PanDengue Net Initiative
edited by and Jorge Osorio
submission deadline 31 Aug 2025 | 3 articles | Viewed by 3191 | Submission Open
Keywords: dengue; zika; chikungunya; mayaro; aedes; immunology; pathogenesis; vector control
(This special issue belongs to the Section General Virology)
Antiviral Agents to Influenza Virus 2025
edited by Wu Zhong and
submission deadline 31 Aug 2025 | 2 articles | Viewed by 2998 | Submission Open
Keywords: influenza; antiviral drug; drug resistance; antiviral drug target
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Viral Mechanisms of Immune Evasion
edited by
submission deadline 31 Aug 2025 | 3 articles | Viewed by 2521 | Submission Open
Keywords: immune evasion; virulent factor; antiviral signaling; pathogenesis; antiviral strategy
(This special issue belongs to the Section General Virology)
Pathogenesis of Flavivirus Infections
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 2323 | Submission Open
Keywords: pathogenesis; immunopathogenesis; immune response; clinical outcomes; vaccines; diagnostic; public health; one health; molecular biology; flavivirus; computer simulation; artificial intelligence
(This special issue belongs to the Section General Virology)
Influenza and Other Respiratory Viruses: Prevention, Diagnosis, Treatment: 2nd Edition
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 2223 | Submission Open
Keywords: influenza; adenovirus; coronoavirus; respiratory syncytial virus; rhinovirus; respiratory virus; antiviral strategies; epidemiology; diagnosis; treatment; vaccination; surveillance; vaccine development
(This special issue belongs to the Section Animal Viruses)
Rodent-Borne Viruses 2025 submission deadline 31 Aug 2025 | 1 articles | Viewed by 1841 | Submission Open
Keywords: rodent-borne viruses; hantaviridae; arenaviridae; poxviridae; zoonosis; virus ecology and evolution; virus– host interaction; virus discovery; animal model; rodents
(This special issue belongs to the Section Animal Viruses)
Bovine Viral Diarrhea Viruses and Other Pestiviruses
edited by
submission deadline 31 Aug 2025 | 3 articles | Viewed by 1755 | Submission Open
Keywords: epidemiological survey; prevalence; seroprevalence; bovine viral diarrhoea; mucosal disease; neutralizing antibodies; taxonomy; antiviral drugs; vaccines; species and subgenotypes; wild animal
(This special issue belongs to the Section Animal Viruses)
Roles of Macrophages in Viral Infections, 2nd Edition
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 1379 | Submission Open
Keywords: macrophage; microglia; Kupffer cells; viral infection; antiviral immunity; inflammatory cytokines; langerhans cell; antiviral drugs; viral pathogenesis
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
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