Special Issues

Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Nanomedicines for Overcoming Tumor Immunotherapy Tolerance
edited by Yaping Li
submission deadline 31 Jan 2026 | 5 articles | Viewed by 9717 | Submission Open
Keywords: tumor immunotherapy; immunotherapy tolerance; nanomedicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Biomedical Applications of Nanocarriers in Targeted Delivery of Bioactive Compounds submission deadline 31 Jan 2026 | 4 articles | Viewed by 6082 | Submission Open
Keywords: absorption; bioavailability; bioactive compounds; drug delivery systems; nanoencapsulation; nanomaterials; nanocarrier systems; natural compounds; oral administration; precision therapy; targeted delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Controlled-Release Drug Delivery Systems for Anti-Inflammatory and Wound Healing Action
edited by , and Anica M. Petrović
submission deadline 31 Jan 2026 | 4 articles | Viewed by 6060 | Submission Open
Keywords: controlled drug delivery systems; systems for topical delivery; physicochemical characterization; stability studies; rheological properties; release and permeation testing; anti-inflammatory properties; wound-healing properties; natural products
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Bioactive Compounds and Nanotechnology: Sustainable Approaches for Pharmaceutical Applications submission deadline 31 Jan 2026 | 5 articles | Viewed by 5036 | Submission Open
Keywords: natural bioactive compounds; biotechnological drug production; therapy; green cosmetics; eco-friendly pharmacy; natural preservatives; pharmaceutical formulation; nanomedicine; sustainability; green chemistry; green nanotechnology; sustainable drug delivery systems; controlled-release systems; nanocarriers for drug bioavailability; phytochemical-based drug therapies; lifecycle analysis of drug manufacturing; natural compounds in drug formulation; sustainable packaging for pharmaceuticals
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advances in Physiologically Based Pharmacokinetic (PBPK) Modeling and Applications
edited by
submission deadline 31 Jan 2026 | 3 articles | Viewed by 4994 | Submission Open
Keywords: physiologically based pharmacokinetic (PBPK) modeling; IVIVE; pharmacokinetics; ADME; modeling and simulation; PK/PD; biopharmaceutics; quantitative systems pharmacology
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Nanoparticle-Based Gene Delivery
edited by Xiubo Zhao and
submission deadline 31 Jan 2026 | 3 articles | Viewed by 4194 | Submission Open
Keywords: nanaoparticles; gene delivery; nucleic acids; DNA; RNA; gene therapy
(This special issue belongs to the Section Gene and Cell Therapy)
Drug Formulation Design and Pharmacokinetics for the Treatment of Skin Diseases submission deadline 31 Jan 2026 | 2 articles | Viewed by 3802 | Submission Open
Keywords: pharmacokinetic studies of topical and transdermal therapies; advanced techniques for assessing drug penetration and distribution; optimization of therapeutic efficacy and safety profiles; dermatological drug delivery; topical formulations; skin pharmacokinetics; drug penetration; transdermal patches; creams and gels
(This special issue belongs to the Section Biopharmaceutics)
Integrating Phytocompounds with Nanotechnology: Revolutionary Approaches to Antimicrobial, Antioxidant, and Anti-Tumoral Therapies submission deadline 31 Jan 2026 | 3 articles | Viewed by 3553 | Submission Open
Keywords: bioactive phytocompounds  ; nanotechnology; nanomedicine; antimicrobial; antioxidant; anti-tumoral; drug delivery; plant-based therapeutics; phytochemical nanocarriers
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advances in Drug Delivery Systems for the Management of Metabolic Diseases submission deadline 31 Jan 2026 | 3 articles | Viewed by 3238 | Submission Open
Keywords: drug delivery systems; metabolic diseases; nanotechnology; synthetic drugs and natural extracts; preclinical and clinical studies
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Synergistic Nanomedicines: Integrating Chemotherapy and Phototherapy for Enhanced Cancer Treatment
edited by Nasrin Hooshmand
submission deadline 31 Jan 2026 | 1 articles | Viewed by 2976 | Submission Open
Keywords: nanomaterial; nanomedicine; chemo-photothermal therapy; cancer; drug delivery
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Recent Advances in Nanotechnology-Based Approaches for Pharmaceutical Applications, 2nd Edition submission deadline 31 Jan 2026 | 2 articles | Viewed by 2568 | Submission Open
Keywords: nanoparticles; drug delivery; biological barriers; pharmaceutical; diagnosis; therapy; efficacy and safety assessment; in vitro and in vivo studies
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Drug Products: Latest Trends in Technical Development and Manufacturing of Parenteral Products
edited by Andrea Allmendinger and Hanns-Christian Mahler
submission deadline 31 Jan 2026 | 2 articles | Viewed by 2486 | Submission Open
Keywords: parenteral products; sterile manufacturing; biopharmaceuticals; protein stability; cell and gene therapy; formulation development; aseptic manufacturing; Annex 1; sustainability; device integration; container closure integrity; analytical characterization; primary packaging material; single-use technologies; visual inspection; particulate matter; real-time release; subcutaneous administration
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Nanocarrier-Based Antibacterial Agents and Formulations submission deadline 31 Jan 2026 | 1 articles | Viewed by 2220 | Submission Open
Keywords: antibacterial agent-loaded nanocarriers; antibiotic resistance; drug delivery; nanotechnology; pharmaceutics
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Polymeric Materials and Drug Delivery Systems for Dental and Oral Health Applications submission deadline 31 Jan 2026 | 3 articles | Viewed by 2201 | Submission Open
Keywords: prevention; dentistry; regeneration; drug delivery systems; antimicrobial properties; topical delivery; cancer therapy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Drug Delivery, Diagnostics, and Therapeutics for Cancer: Toward Personalized Oncology
edited by , , Nelofer Syed and
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1971 | Submission Open
Keywords: personalized medicine; cancer diagnostics; cancer therapeutics; cancer theranostics; radiotherapeutics; precision oncology; targeted therapy; immunotherapy; molecular diagnostics; biomarkers in cancer; cancer genomics; tumor microenvironment; surgical oncology; cancer biomarkers; AI in cancer diagnosis; multimodal cancer treatment; advanced imaging in oncology
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Functional Nanomaterials in Pharmaceutical and Biomedical Applications submission deadline 31 Jan 2026 | 1 articles | Viewed by 1645 | Submission Open
Keywords: nanomaterials; drug delivery; bioimaging; tissue engineering; gene transfection; hyperthermic therapies; photodynamic therapies; photoacoustic therapies
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
CNS Drug Delivery: Recent Advances and Challenges
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1543 | Submission Open
Keywords: CNS drug delivery; blood– brain barrier; nanotechnology; targeted delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Antibacterial Nanoformulations Based on Natural Products
edited by , and Enrique Werner
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1307 | Submission Open
Keywords: nanoformulation; essential oil; extract; semisynthetic compound; hybrid compound; resinous exudate; antimicrobial agents; natural products
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advances in Chemically Crosslinked Hydrogels at Different Scale Levels as Versatile Drug Delivery Systems in the Biomedical Field
edited by and Roberta Pappalardo
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1076 | Submission Open
Keywords: hydrogels; chemically crosslinked hydrogels; bulk hydrogels; macro-scale hydrogels; micro-scale hydrogels; nano-scale hydrogels; hydrogel-based drug delivery systems; advanced therapies
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Innovative Viral and Non-Viral Vectors for Drug Delivery, Vaccine Development, Therapeutic Applications and Diagnosis submission deadline 31 Jan 2026 | 1 articles | Viewed by 850 | Submission Open
Keywords: viral vector engineering; non-viral delivery systems; vaccine development; infection management; drug delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Inflammation-Targeted Nanomedicines for the Treatment of Chronic Inflammatory Diseases and Cancer
edited by and
submission deadline 31 Jan 2026 | 1 articles | Viewed by 652 | Submission Open
Keywords: Alzheimer’ s disease; atherosclerosis; cancer; chronic inflammation; chronic respiratory diseases; diabetes; immunomodulation; inflammation-responsive drug delivery systems; inflammatory bowel disease; multiple sclerosis; nanomedicine; novel biomaterials; rheumatoid arthritis; targeted drug delivery
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Emerging Strategies to Enhance Solubility of Poorly Soluble Drugs: From Nanosystems to Molecular Innovations submission deadline 31 Jan 2026 | 1 articles | Viewed by 615 | Submission Open
Keywords: poorly soluble drugs; solubility enhancement; nanotechnology; amorphous solid dispersions; cyclodextrin complexation; co-crystallization; ionic liquids; deep eutectic solvents; prodrug design; formulation technologies
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Lipid-Based Nanoparticulate Drug Delivery Systems: Preparation, Biomedical Applications, and Evaluation, 2nd Edition submission deadline 31 Jan 2026 | 1 articles | Viewed by 427 | Submission Open
Keywords: liposomes; nanoemulsions; nanostructured lipid carriers; niosomes; solid lipid nanoparticles; targeted drug delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Novel In Silico Supported Approaches for the Development and Delivery of Drugs for Antimicrobial Therapy and Neurodegenerative Diseases
edited by
submission deadline 31 Jan 2026 | Viewed by 419 | Submission Open
Keywords: antibacterials; antibiotics; chemotherapeutics; antivirals; antineurodegenerative; CADD; in silico drug design; drug delivery; in silico modeling; bioinformatics; machine learning; repurposing
(This special issue belongs to the Section Drug Targeting and Design)
Innovative Nano-Delivery Systems for Enhanced Oral Disease Therapies
edited by , and Elena Dinte
submission deadline 31 Jan 2026 | Viewed by 401 | Submission Open
Keywords: drug delivery systems; oral diseases; nanomaterials; nanoformulations; biomaterials; natural compounds
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advances in Inhalation Formulations: Innovations and Analytical Approaches for Pulmonary and Nasal Drug Delivery
edited by Helvécio Vinicius Antunes Rocha and
submission deadline 31 Jan 2026 | Viewed by 311 | Submission Open
Keywords: inhalation formulation; pulmonary delivery; nasal delivery
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advances in Drug Delivery Systems for Leishmaniasis Therapy
edited by Elizabeth Igne Ferreira, Jeanine Giarolla and Soraya Da Silva Santos
submission deadline 31 Jan 2026 | Viewed by 283 | Submission Open
Keywords: delivery systems; leishmanicides; bioactive compounds in Leishmania sp.; advanced systems for drug delivery; oral and topical administration
(This special issue belongs to the Section Drug Targeting and Design)
Recent Advances in Cancer Treatment and Drug Delivery with a Focus on Coinage Metals (Copper, Silver and Gold) submission deadline 31 Jan 2026 | Viewed by 283 | Submission Open
Keywords: cancer; copper; silver; gold; drug delivery systems; drug release; cancer therapy; chemotherapy; coinage metals
(This special issue belongs to the Section Drug Targeting and Design)
Bioactive Phytochemicals from Medicinal Plants: Formulation and Therapeutic Potential submission deadline 31 Jan 2026 | Viewed by 229 | Submission Open
Keywords: bioactive phytochemicals; medicinal plants; standardisation; green extraction; phytochemical synergy; dose optimisation; formulation; chronic disease therapeutics
(This special issue belongs to the Section Biopharmaceutics)
Magnetic Nanoparticles in Regenerative Medicine and Tissue Engineering
edited by Mauricio César De Marzi and
submission deadline 31 Jan 2026 | Viewed by 223 | Submission Open
Keywords: magnetic nanoparticles; regenerative medicine; tissue engineering; targeted drug delivery; magnetically responsive scaffolds
Advances in Delivery Systems for Antidiabetic Drugs and Beyond Glycaemic Control submission deadline 31 Jan 2026 | Viewed by 187 | Submission Open
Keywords: diabetes; biopolymers; patches; nanocarriers; inserts; pharmacokinetics; diagnostics; devices
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Molecular Strategies to Enhance Drug Solubility submission deadline 31 Jan 2026 | Viewed by 145 | Submission Open
Keywords: drug solubility; molecular strategies; co-crystals; amorphous solid dispersions; co-amorphous systems; salt formation; prodrugs; molecular complexation; solubility enhancement; pharmaceutical formulation
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Targeted Drug Delivery Strategies for Infectious Diseases
edited by Danielle Lazarin Bidóia, Daniele Stéfanie Sara Lopes Lera-Nonose and
submission deadline 31 Jan 2026 | Viewed by 141 | Submission Open
Keywords: infectious disease; treatment; delivery system; biomaterial; targeted drug therapy; liposome; dendrimer; nanotube; nanotechnology; formulation; polymer; antifungal; antimicrobial; antiparasitic; antibiotic; bacterial infection; adjuvant; antiviral; biofilm-related infection; bacteria; antiparasitic
(This special issue belongs to the Section Drug Targeting and Design)
Pharmaceutical Applications of Therapeutic Deep Eutectic Systems (THEDES) submission deadline 31 Jan 2026 | Viewed by 139 | Submission Open
Keywords: eutectic systems; therapeutic deep eutectic systems; natural deep eutectic systems; biomedicine; drug delivery systems; bioavailability; antimicrobial; cancer; anti-inflammatory; antioxidant
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Recent Advances in Metal-Based Drug Delivery Systems for Cancer Therapy submission deadline 31 Jan 2026 | Viewed by 134 | Submission Open
Keywords: metal-based drug delivery systems; cancer therapy; stimuli-responsive prodrugs; nanomedicine; coordination complexes; targeted chemotherapy
(This special issue belongs to the Section Drug Targeting and Design)
Emerging Trends in Smart Theranostic Nanomedicine
edited by , and Thavasyappan Thambi
submission deadline 31 Jan 2026 | Viewed by 115 | Submission Open
Keywords: various types of nanoparticles; smart nanomaterials; theranostic agents; diagnostics; synthesis and characterization; drug delivery system; in vitro and in vivo studies; synergistic therapy; cancer therapy; microbial infections; multimodal imaging; theranostics; tumor and microbial targeting
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Bio-Based Materials and Personalized Medicine: Innovative Applications in Tissue Engineering and Drug Delivery submission deadline 31 Jan 2026 | Viewed by 115 | Submission Open
Keywords: bio-based materials; biocompatibility; sustainability; extracellular matrix; customized scaffolds; drug delivery; controlled drug delivery systems; tissue engineering; tissue regeneration; personalized medicine
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advanced Metal-Based Nano-Drug Delivery Systems for Antimicrobial Therapy
edited by
submission deadline 31 Jan 2026 | Viewed by 115 | Submission Open
Keywords: nanosystems; micelles; liposomes; nanoparticles; metal-based drugs; drug delivery; antimicrobial therapy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advanced Theranostic Nanoplatforms for Precision Therapy
edited by and Secheol Oh
submission deadline 31 Jan 2026 | Viewed by 113 | Submission Open
Keywords: theranostic nanoplatforms; extracellular vesicles (EVs); targeted drug delivery; stimuli-responsive nanomaterials; antimicrobials; cancer and infectious disease therapy; nanomedicine; biocompatible nanomaterials; real-time imaging; modular nanostructures; precision medicine; bacterial ghost
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Nanoparticles for Dermal and Transdermal Delivery
edited by Nina Dragićević
submission deadline 31 Jan 2026 | Viewed by 107 | Submission Open
Keywords: nanoparticles; nanocarriers; lipid-based nanoparticles; polymeric nanoparticles; metallic nanoparticles; dermal delivery; transdermal delivery; skin permeation; drug delivery systems
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Pharmaceutics, Genomics, and Biotechnology for Liver Disease Therapy submission deadline 31 Jan 2026 | Viewed by 89 | Submission Open
Keywords: liver disease; nanocarriers; lipid nanoparticles; gene therapy; bioengineered scaffolds; biotechnological innovation; drug delivery; pharmaceutical formulation
(This special issue belongs to the Section Drug Targeting and Design)
Aerogels for Regenerative Medicine and Pharmaceutical Technology submission deadline 31 Jan 2026 | Viewed by 79 | Submission Open
Keywords: aerogels; tissue engineering; regenerative medicine; drug delivery; pharmaceutical technology; polymers
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Innovations in Preclinical Drug Development: Efficacy, Safety, and Translational Strategies
edited by Xi Xu and Hongxi Wu
submission deadline 31 Jan 2026 | Viewed by 79 | Submission Open
Keywords: preclinical drug development; drug design; advanced disease models; three Rs principles; molecular glue degrader; antibody-drug conjugate; glutamine metabolism
(This special issue belongs to the Section Drug Targeting and Design)
Microfluidic Devices for Encapsulating and Delivering Large Biomolecules
edited by , Hema Choudhary and Sheng Zhao
submission deadline 31 Jan 2026 | Viewed by 78 | Submission Open
Keywords: microfluidics; lipid nanoparticles; biohybrid and biomimetic nanoparticles; nucleic acid delivery; delivery vectors; microfluidic mixing; droplet microfluidics; protein delivery; encapsulation; vaccine development; microgels; single-cell sequencing; biomolecules
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Dendrimer-Mediated Drug, Gene, and Protein Delivery for Disease Treatment submission deadline 31 Jan 2026 | Viewed by 76 | Submission Open
Keywords: dendrimers; drug delivery; gene delivery; protein delivery; targeted therapy; bioconjugation; controlled release; tumor therapy; inflammatory diseases; infectious diseases
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Prodrug Applications for Targeted Cancer Therapy
edited by René C.-Gaudreault and Atziri Corin Chavez Alvarez
submission deadline 31 Jan 2026 | Viewed by 75 | Submission Open
Keywords: anticancer agents; prodrugs; targeted cancer therapy; precision medicine; translational oncology; structure– activity relationship; clinical oncology
(This special issue belongs to the Section Drug Targeting and Design)
Innovative Oral and Topical Drug Delivery Systems for Enhanced Bioavailability
edited by , Alvaro Jimenez-Kairuz and José Bermudez
submission deadline 31 Jan 2026 | Viewed by 65 | Submission Open
Keywords: oral drug delivery; topical formulations; bioavailability enhancement; polymeric drug delivery systems; mucoadhesive systems; solubility and permeability improvement; in situ forming systems; 3D printing in pharmaceutics
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Innovations in Drug Delivery: Tackling Challenges and Exploring Emerging Trends submission deadline 31 Jan 2026 | Viewed by 38 | Submission Open
Keywords: nanoformulations; drug delivery; nanocytotoxicity; nanomedicine; bio-based nanoformulations
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Hydrogels-Based Drug Delivery System for Wound Healing submission deadline 10 Feb 2026 | 1 articles | Viewed by 890 | Submission Open
Keywords: controlled drug release; polymer-based hydrogels; advanced wound dressings; smart hydrogels for tissue regeneration; bioactive hydrogels; 3D-printed hydrogels for personalized wound dressings
(This special issue belongs to the Section Drug Delivery and Controlled Release)
In Situ-Applied Drug Formulation
edited by Di Wen
submission deadline 10 Feb 2026 | Viewed by 179 | Submission Open
Keywords: in situ formulations; drug delivery; controlled drug release
(This special issue belongs to the Section Biopharmaceutics)
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