Special Issue "Nanobiotechnology in Medicinal Chemistry"
A special issue of Pharmaceuticals (ISSN 1424-8247).
Deadline for manuscript submissions: closed (30 June 2016)
Dr. Alexandru Mihai Grumezescu
Department of Science and Engineereing of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, Politehnica University of Bucharest, RO-011061, Bucharest, Romania
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Interests: synthesis and characterization of nanobiomaterials; pharmaceutical nanotechnology; drug targeting; drug delivery; anti-biofilm surfaces; nanomodified surfaces; thin films; natural products
In recent years, nanotechnology has made significant progress in developing tailored materials and structures with nanometric size for improving different biomedical applications. Inorganic, organic, and mixed (organic–inorganic) nanomaterials currently offer unlimited perspectives for improved and new biomedical applications. The medical field has benefited, in both diagnosis and therapy, by the development of nanostructured drug delivery systems, novel tailored surfaces, and improved materials for implantable and exploratory devices. Most of the recently developed nanomaterials have improved biocompatibility and utilize green technologies for the development of functionalized materials with medical use. Moreover, this approach offers a significant impact on the development of personalized medicine by creating novel and alternative therapeutic strategies for difficult to treat and currently incurable diseases.
Regarding diagnosis, the most important progress has been made on imaging, while for therapy—on targeting. Cancer diagnosis and therapy represents one of the fields that benefited the most from the applications of nanobiotechnology in medicine. Different nanosystems utilized for the stabilization, targeting and controlled delivery or drugs have flourished in recent years. Moreover, another priority field, currently highly-investigated in the medical area—resistant infections, has benefited by the development of nanoparticles able to destroy resistant pathogens and multicellular microbial communities (biofilms), which are tolerant to high amounts of current antimicrobials. Different polymeric nanomaterials have been developed using green technologies in order to reduce the environmental damage and increase biodegradability. Many of the obtained nanomaterials with biological applications currently offer great perspectives for the development of alternative therapies, and may be successfully utilized to replace current inefficient approaches or the complete them.
The proposed topics include, but are not limited to:
-Nanotechnology for cancer therapy
-Nanoparticles in imaging and diagnosis
-Improved nanomaterials for a green medical society
-Nanostructured coatings for biofilm control
-Nanoarchitectonics for improved drug delivery
-Inorganic versus organic nanoparticles in biomedical applications
-Surface nanomodified prosthetic devices
-Synthesis and characterization of nanoparticles for biomedical use
Dr. Alexandru Mihai Grumezescu
Dr. Alina Maria Holban
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 850 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.