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Pathogens publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Ticks and Tick-Borne Pathogens in a Changing World

edited by Roxanne A. Charles and Sebastián Muñoz-Leal

submission deadline 10 Jul 2026 | 7 articles | Viewed by 11868 | Submission Open

Keywords: ticks; tick-borne pathogens; tick-borne diseases; climate change; One Health; diagnostics; emerging and re-emerging tick-borne pathogens; tick ecology

(This special issue belongs to the Section Ticks)

Fighting Pathogens with Natural Antimicrobials

edited by

Tomasz M. Karpiński

and

Marcin Ożarowski

submission deadline 10 Jul 2026 | 4 articles | Viewed by 5455 | Submission Open

Keywords: in vitro testing; in silico testing; antimicrobial activities; drug resistance; natural products; plant extracts; essential oils; bee products; natural antibiotics; anti-biofilm activity

Leptospira and Leptospirosis: New Insights into an Old Disease

edited by

Sabina Kędzierska-Mieszkowska

submission deadline 10 Jul 2026 | 4 articles | Viewed by 2017 | Submission Open

Keywords: Leptospira; leptospirosis; bacterial pathogenesis; infection; virulence; host–pathogen interactions; zoonosis

The Role of Vaccines in the Prevention and Control of Infectious Diseases

edited by Rajesh Kumar Radhakrishnan and

Raja Veerapandian

submission deadline 10 Jul 2026 | 1 articles | Viewed by 1075 | Submission Open

Keywords: vaccination routes; mRNA vaccines; vaccine formulations; host immunity

(This special issue belongs to the Section Vaccines and Therapeutic Developments)

Understanding the Dynamics of HIV Reservoirs Is Fundamental for Finding a Potential HIV Cure

edited by Germán Gornalusse and Sulggi Lee

submission deadline 10 Jul 2026 | Viewed by 424 | Submission Open

Keywords: HIV reservoir; HIV latency; HIV cure

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Viral Hepatitis Among Specific Populations: Epidemiology, Transmission, Treatment, and Prevention

edited by

Aldemir B. Oliveira-Filho

submission deadline 15 Jul 2026 | 7 articles | Viewed by 18128 | Submission Open

Keywords: epidemiology; diagnosis; prevention; control; access and care strategies

(This special issue belongs to the Section Viral Pathogens)

Virulence Mechanisms Used by Pathogens Related to Human, Animal, and Environmental Health

edited by

Claudia León-Sicairos

Nidia M. León-Sicairos

and

Adrian Canizalez-Roman

submission deadline 15 Jul 2026 | 4 articles | Viewed by 10922 | Submission Open

Keywords: virulence mechanisms; pathogens; global health; pathogenicity; virulence factors

Understanding Emerging and Re-Emerging Viral Infections

edited by

Jose Angel Regla Nava

submission deadline 15 Jul 2026 | 2 articles | Viewed by 5079 | Submission Open

Keywords: diagnosis; pathogenesis; evolution; epidemiology; drugs; vaccines

(This special issue belongs to the Section Viral Pathogens)

Occupational Exposure to Zoonotic Vector-Borne Diseases: Risks, Prevention, and Emerging Challenges

edited by

Angela Stufano

submission deadline 15 Jul 2026 | Viewed by 554 | Submission Open

Keywords: zoonotic vector-borne diseases; ZVBDs; preventive strategies

A Journey Through Forest Pathology: Lessons from History and Emerging Innovations

edited by

Anna Maria Vettraino

and

Luisa Ghelardini

submission deadline 15 Jul 2026 | Viewed by 288 | Submission Open

Keywords: forest pathogens; urban plant pathogens; early detection technologies; integrated disease management

Cutaneous Fungal Infections

edited by

Daniel Wagner Santos

, Conceição Azevedo and Dallas Smith

submission deadline 15 Jul 2026 | Viewed by 254 | Submission Open

Keywords: epidemiology; diagnostic innovation; antifungal resistance

(This special issue belongs to the Section Fungal Pathogens)

Antimicrobial Resistance in the Post-COVID Era: A Silent Pandemic

edited by

Vasileios Petrakis

and Maria Panopoulou

submission deadline 20 Jul 2026 | 7 articles | Viewed by 13578 | Submission Open

Keywords: COVID-19 pandemic; antimicrobial resistance; bloodstream infections; multidrug-resistant bacteria; infection prevention and control group; antibiotic stewardship

Covalent Inhibitors of Pathogenic Bacterial, Protozoal, Viral, and Fungal Targets

edited by

Monika I. Konaklieva

and Balbina J. Plotkin

submission deadline 20 Jul 2026 | 5 articles | Viewed by 7875 | Submission Open

Keywords: covalent inhibitors; pathogenic bacterial and viral protein targets; protozoa; fragment-based drug discovery; chemical warheads; prodrugs; STD NMR; MS; SITE (single-injection thermal extinction)

Current Research on Bacillus anthracis Infection

edited by Viviana Manzulli and

Domenico Galante

submission deadline 20 Jul 2026 | 3 articles | Viewed by 6605 | Submission Open

Keywords: Bacillus anthracis; epidemiology; pathogenesis; diagnostics; genomics

(This special issue belongs to the Section Bacterial Pathogens)

Advances in Rapid Detection and Quantification of Campylobacter in Food Safety

edited by Elena George Olson and Aaron R. Bodie

submission deadline 20 Jul 2026 | 3 articles | Viewed by 1832 | Submission Open

Keywords: Campylobacter jejuni detection; rapid molecular diagnostics; foodborne pathogens; PCR-based detection; enrichment medium optimization; quantification methods; poultry microbiology; food safety monitoring; culture-based vs. molecular methods; high-throughput screening; microbial load assessment; real-time PCR (RT-PCR); biosensors in food safety; pathogen enumeration; sample matrix effects

(This special issue belongs to the Section Bacterial Pathogens)

Emerging Trends in Arbovirus Research: Diagnosis, Transmission, and Therapeutic Development

edited by

Paulo Ricardo da Silva Sanches

submission deadline 20 Jul 2026 | 1 articles | Viewed by 985 | Submission Open

Keywords: arboviruses; vector-borne diseases; viral pathogenesis; molecular diagnostics; antiviral therapies; vaccine develop-ment; vector control; infectious diseases

(This special issue belongs to the Section Viral Pathogens)

Prion and Prion-Like Protein Misfolding: Mechanisms, Diagnostics, and Therapeutic Prospects

edited by Wen-Quan Zou,

Katsuya Satoh

and Gang Wang

submission deadline 20 Jul 2026 | Viewed by 296 | Submission Open

Keywords: prions; prion diseases; prion-like; neurodegenerative disorders; protein misfolding disorders; protein aggregations; biomarkers; neuroscience; Alzheimer’s disease; Parkinson’s disease; tau; α-synuclein

Molecular Mechanisms Governing the Environmental Fate of Bacterial and Viral Pathogens

edited by Justin Greaves and

Samendra Sherchan

submission deadline 20 Jul 2026 | Viewed by 288 | Submission Open

Keywords: decay; transport; viruses; infectivity; disinfection

Classic and Emerging Pathogens as a Cause of Healthcare-Associated Infections: Current Knowledge and Future Approaches

edited by

Alessio Facciolà

and

Antonio Laganà

submission deadline 30 Jul 2026 | 6 articles | Viewed by 17526 | Submission Open

Keywords: antimicrobial resistance; epidemiology; healthcare-associated infections; microbiology; preventive medicine; public health

Epidemiology of Respiratory Syncytial Virus and Potential Public Health Impact of Vaccination

edited by Fabio Tramuto

submission deadline 30 Jul 2026 | 4 articles | Viewed by 11888 | Submission Open

Keywords: respiratory syncytial virus; epidemiology; public health; co-infections; re-infection; vaccines; monoclonal antibodies; molecular surveillance; genomics

(This special issue belongs to the Section Viral Pathogens)

Current Advances in Pathogen Diagnosis and Discovery Methods

edited by

Cheng Guo

submission deadline 30 Jul 2026 | 2 articles | Viewed by 8415 | Submission Open

Keywords: infectious diseases; diagnostics; omics; One Health

(This special issue belongs to the Section Viral Pathogens)

From Commensal to Pathogen: The Dynamics of Host–Microbiome Interactions

edited by

Patricia Agudelo-Romero

submission deadline 30 Jul 2026 | Viewed by 301 | Submission Open

Keywords: host–microbiome interactions; single- and multi-kingdom microbiome (bacteria, fungi, viruses); microbiome dynamics and dysbiosis; multi-omics and systems biology; microbial ecology and disease

Parasitic Diseases in the Contemporary World

edited by

Krzysztof Korzeniewski

and

Danuta Izabela Kosik-Bogacka

submission deadline 31 Jul 2026 | 17 articles | Viewed by 36225 | Submission Open

Keywords: protozoa; helminths; neglected tropical diseases; epidemiology; diagnostics; treatment; prevention

(This special issue belongs to the Section Parasitic Pathogens)

Parasitic Helminths and Control Strategies

edited by

Jackson Victor de Araújo

and

Luís Madeira de Carvalho

submission deadline 31 Jul 2026 | 11 articles | Viewed by 20611 | Submission Open

Keywords: control of helminthosis; biological control; vaccines; resistant breeds; diagnostics of helminths; epidemiology of helminths; chemical and phytotherapeutic anthelmintics; One Health

(This special issue belongs to the Section Parasitic Pathogens)

Emerging/Re-Emerging Viruses and Antiviral Drug Design

edited by Dongxiao Liu, Zhiqing Zhang, Ishita Roy Chowdhury and

Pawel Zmora

submission deadline 31 Jul 2026 | 4 articles | Viewed by 17990 | Submission Open

Keywords: emerging viruses; influenza viruses; coronavirus; flaviviruses; enteroviruses; antiviral design

(This special issue belongs to the Section Viral Pathogens)

Monitoring and Management of Mosquito-Borne Pathogens in Mosquito Populations

edited by

Bethany Bolling

and Hannah Romo

submission deadline 31 Jul 2026 | 3 articles | Viewed by 3181 | Submission Open

Keywords: mosquitoes; arboviruses; surveillance; mosquito collection; mosquito testing; integrated mosquito management; mosquito control; response plans; outbreak response

Advances in Molecular Epidemiology and Innovative Diagnostic Strategies for Infectious Disease Control

edited by

Ko Ko

, Inn Kynn Khaing and

Zayar Phyo

submission deadline 31 Jul 2026 | 2 articles | Viewed by 2388 | Submission Open

Keywords: elimination; eradication; surveillance; diagnostics; screening; epidemiology; pathogens; outbreaks; genomics; sequencing; CRISPR; point-of-care; modelling; innovation; preparedness

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Natural Products Chemistry: Innovation and New Frontiers in Antiparasitic Therapies

edited by

Raymundo Alejandro Pérez Hernández

Ramiro Quintanilla-Licea

Eduardo Sánchez-García

and

Joel Horacio Elizondo Luevano

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2367 | Submission Open

Keywords: natural products; antiparasitic activity; medicinal plants; microorganisms; marine organisms; animal byproducts; in vitro, in vivo, and in silico approaches; natural products chemistry; pharmacognosy; innovative therapies; ethnopharmacology; micro-nanoparticles; targeted therapy; epidemiology; purification and extraction; ligand– receptor activity

(This special issue belongs to the Section Parasitic Pathogens)

Advances in Molecular Characterization and Epidemiology of Plant Viruses

edited by

Nicolas Bejerman

submission deadline 31 Jul 2026 | 2 articles | Viewed by 2312 | Submission Open

Keywords: plant viruses; metatranscriptomics; epidemiology; viral diseases; virus detection

(This special issue belongs to the Section Viral Pathogens)

Viral Oncology and Targeted Therapies for Virus-Associated Cancers

edited by

Yonggang Pei

and Hua Zhang

submission deadline 31 Jul 2026 | 2 articles | Viewed by 2087 | Submission Open

Keywords: viral oncoproteins; oncolytic viruses; antiviral therapy; cancer immunotherapy

(This special issue belongs to the Section Viral Pathogens)

Advances in Fungal Pathogenesis and Antifungal Resistance

edited by

Rishabh Sharma

and

Katrina Ramonell

submission deadline 31 Jul 2026 | 2 articles | Viewed by 1488 | Submission Open

Keywords: antifungal resistance; Candida albicans; Aspergillus fumigatus; cryptococcus neoformans; biofilm; antifungal tolerance; metabolic adaptation; stress-response pathways; nutrient acquisition; cell wall modulation; ergosterol biosynthesis; combination therapy

(This special issue belongs to the Section Fungal Pathogens)

Parasites Circulation Between the Three Domains of One Health

edited by

Gábor Nagy

and

Ágnes Csivincsik

submission deadline 31 Jul 2026 | 1 articles | Viewed by 968 | Submission Open

Keywords: parasites of shared habitats; anthelmintic resistance; emerging parasites; climate sensitive parasitic infections; One Health approach to parasitic diseases; livestock-health-related human-wildlife conflicts; other aspects of the livestock-wildlife interface

(This special issue belongs to the Section Parasitic Pathogens)

Porcine/Farm Animal Respiratory Pathogens: Pathogenesis, Diagnostics and Antimicrobial Resistance

edited by

Andrei Ungur

and

Levon Abrahamyan

submission deadline 31 Jul 2026 | 1 articles | Viewed by 859 | Submission Open

Keywords: porcine respiratory pathogens; pathogenesis; diagnostic methods; antimicrobial resistance; swine health management; respiratory disease complex; farm animal pathogens; surveillance and molecular epidemiology; one health

Structure-Based Antiviral Drug Discovery

edited by

Zhao Wang

and Boshi Huang

submission deadline 31 Jul 2026 | 1 articles | Viewed by 808 | Submission Open

Keywords: structure-based drug discovery; antiviral drugs; viral targets; structural biology; drug design

(This special issue belongs to the Section Viral Pathogens)

Advances in Tick Control

edited by Fábio Barbour Scott,

Yara Peluso Cid

, Thais Ribeiro Correia Azevedo and Diefrey Campos

submission deadline 31 Jul 2026 | 1 articles | Viewed by 773 | Submission Open

Keywords: acaricides; resistance; integrated pest management; biological control; plant-derived bioactive compounds; tick-borne diseases; host–parasite interactions; one health

(This special issue belongs to the Section Ticks)

Genomic Applications in Microbial Adaptation, Antimicrobial Resistance and One Health Perspectives

edited by

Wellington Rodrigues

Aristóteles Góes-Neto

and Siomar de Castro Soares

submission deadline 31 Jul 2026 | Viewed by 481 | Submission Open

Keywords: genomics; One Health; antimicrobial resistance; pathogen evolution; metagenomics; reverse vaccinology; zoonotic diseases; mobilome; genomic surveillance; predictive modeling

Viral Vectored Vaccines: From Design to Clinical Implementation for Emerging Pathogens

edited by Alina Tscherne and

Hinh Ly

submission deadline 31 Jul 2026 | Viewed by 428 | Submission Open

Keywords: preclinical testing; clinical testing; animal models; viral vector vaccines; vaccine innovation; immune response; mucosal vaccines; antigen design; zoonotic diseases; pandemic preparedness

(This special issue belongs to the Section Vaccines and Therapeutic Developments)

Molecular Epidemiology and Host-Pathogen Interactions in Infectious Diseases

edited by

Gopinath Venugopal

, Srijon K. Banerjee and Gokul Raj Kathamuthu

submission deadline 31 Jul 2026 | Viewed by 328 | Submission Open

Keywords: host-pathogen interaction; infection and immunity; innate and adaptive immune responses; public health; epidemiology

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Emerging and Re-Emerging Viral Infections in Animals

edited by

Valeria Listorti

and

Andrea Laconi

submission deadline 31 Jul 2026 | Viewed by 320 | Submission Open

Keywords: emerging infections; re-emerging infections; viruses

(This special issue belongs to the Section Emerging Pathogens)

Biosafety and Biosecurity in Work with Pathogens

edited by

Pavle Banović

and Bill Arndt

submission deadline 31 Jul 2026 | Viewed by 276 | Submission Open

Keywords: biosafety; biosecurity; pathogen inactivation; outbreak; risk

Preclinical Models for Tackling Antimicrobial Resistance: From Bench to Translational Insights

edited by Rakel Arrazuria

submission deadline 31 Jul 2026 | Viewed by 263 | Submission Open

Keywords: antimicrobial resistance; preclinical models; animal models; translational research; host-directed therapy; phage therapy; One Health

New Horizons in Parasitic Infections Research

edited by

Rafaela Regina Fantatto

and

Kentaro Kato

submission deadline 31 Jul 2026 | Viewed by 255 | Submission Open

Keywords: parasitology; parasitic diseases; host–parasite interactions; parasitic infections

(This special issue belongs to the Section Parasitic Pathogens)

Tumor Microbiome: A New Frontier in Cancer Therapy and Vaccines

edited by

Swati Jain

submission deadline 31 Jul 2026 | Viewed by 247 | Submission Open

Keywords: tumor microbiome; cancer therapy; microbial immunomodulation; tumor microenvironment; cancer vaccines; intra-tumoral microbes; microbiome-based therapeutics; host-microbe interactions; microbial biomarkers; immuno-oncology

(This special issue belongs to the Section Vaccines and Therapeutic Developments)

Innovative Anti-Toxoplasma Strategies: Pharmacology and Drug Development

edited by

Chunmei Jin

submission deadline 31 Jul 2026 | Viewed by 238 | Submission Open

Keywords: Toxoplasma gondii; drug discovery; pharmacology; antiparasitic agents; drug repurposing; novel therapeutics; toxoplasmosis; pharmacokinetics; drug resistance

(This special issue belongs to the Section Parasitic Pathogens)

From Animal Health to Public Health: Eco-Epidemiological Pathways of Neglected Tropical Diseases

edited by Gina Polo

submission deadline 31 Jul 2026 | Viewed by 237 | Submission Open

Keywords: neglected tropical diseases; eco-epidemiology; climate change; vector dynamics; host–vector interactions; environmental drivers; public health; community-based research

Antimicrobial Resistance in Klebsiella pneumoniae

edited by

Eduardo Rodriguez-Noriega

and

Dolores Alcantar-Curiel

submission deadline 31 Jul 2026 | Viewed by 228 | Submission Open

Keywords: Klebsiella pneumoniae; multidrug resistant; ESKAPE pathogen; carbapenem resistant; hypervirulent

(This special issue belongs to the Section Bacterial Pathogens)

Bacterial Strategies to Subvert Innate Immune Defenses and Sustain Persistence

edited by

Rajesh Palanisamy

submission deadline 31 Jul 2026 | Viewed by 226 | Submission Open

Keywords: innate immune evasion; bacterial persistence; phagosome maturation; effector proteins nf-κb signaling; inflammasome antagonism; biofilm formation; intracellular survival; cytokine modulation; host–pathogen interaction

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Infection and Immunity in Fish Models: Insights into Host Defense and Inflammation

edited by