The Roles of Maternal and Child Nutrition in Fetal Alcohol Spectrum Disorders (FASD): From Mechanistic Insights to Opportunities for Intervention

Dear Colleagues,

Despite extensive prevention efforts worldwide, fetal alcohol spectrum disorders (FASD) remain the most common preventable cause of neurodevelopmental delay worldwide. Both animal models and human cohort studies have demonstrated important roles of nutrition in the teratogenesis of prenatal alcohol exposure. Chronic alcohol use has been shown to alter nutrient absorption, metabolism, and utilization in non-pregnant adults, and recent studies have begun to elucidate how such alterations may play mechanistic roles in FASD. Animal models have demonstrated the potential for alterations in prenatal and/or postnatal nutrition to modify the teratogenic effects of prenatal alcohol exposure, leading to recent FASD nutritional intervention studies in humans. This special issue of Nutrients showcases important known and novel roles of maternal, fetal, and postnatal nutrition in FASD, with an emphasis on mechanistic insights and nutritional interventions.

Dr. Robert Colin Carter
Guest Editor

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