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The Role of Sports Supplements in Sport Performance

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Sports Nutrition".

Deadline for manuscript submissions: 5 February 2026 | Viewed by 1239

Special Issue Editors


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Guest Editor
Department of Nutrition and Food Science, Campus of Cartuja, University of Granada, 18011 Granada, Spain
Interests: total polyphenols; fruits; nutrition and bromatology; abts; DPPH

Special Issue Information

Dear Colleagues,

"Food first" has been widely accepted as the preferred strategy within sports nutrition, although there is no consensus on its definition, and its implications are often considered in a limited way or only in an educational context. Close et al. (2022) proposed that "food first" should imply that, whenever practically possible, nutrient intake should come from foods and beverages rather than isolated food components or dietary supplements. There are many reasons to recommend a "food first" strategy, including the risk of contamination from supplements, which could lead to violations of anti-doping regulations.

However, some supplements can enhance health and/or performance, meaning, therefore, that a strict food-only approach may be inadequate. Authors have outlined six reasons why a food-exclusive approach may not always be optimal for athletes:

  1. Some nutrients are challenging to obtain in sufficient amounts from the diet, potentially requiring excessive energy intake or the consumption of other nutrients.
  2. Certain nutrients are only abundant in foods that athletes cannot consume or do not prefer.
  3. The nutrient content of some foods with established ergogenic benefits can be highly variable.
  4. Concentrated doses of certain nutrients may be necessary to address deficiencies and/or promote immune tolerance.
  5. Some foods may be difficult to consume immediately before, during, or right after exercise.
  6. Proven supplements might be beneficial when concerns about hygiene or food contamination arise.

In these scenarios, it is acceptable for athletes to consider dietary supplements as long as a comprehensive risk-minimization strategy is implemented. Consequently, it is essential to emphasize that the full saying should be "food first, but not always". It is crucial to highlight that the use of dietary supplements should not compensate for poor food choices and an inadequate diet, except as a short-term strategy when dietary changes are not feasible (Maughan and Shirreffs, 2011).

Likewise, it is important for different professionals and athletes to remember that a well-chosen diet supports the benefits of evidence-based supplements, whether taken to maximize performance, delay fatigue, alter body composition, or improve health (Larson-Meyer, Woolf, Burke, 2018). Ultimately, considering the safety, efficacy, and legality of supplements, as well as their ability to be tailored to the athlete's age and life cycle (Burke and Peeling, 2018), there are specific cases where evidence-based supplementation may be justified.

Prof. Dr. Antonio Jesús Sanchez-Oliver
Prof. Dr. Eduardo Guerra-Hernández
Guest Editors

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Keywords

  • sport nutrition
  • sport supplements
  • sport performance
  • supplement use
  • supplement consumption
  • security
  • evidence
  • legality

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Published Papers (2 papers)

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Research

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7 pages, 197 KB  
Communication
Enhancing Medical Education Through Statistics: Bridging Quantitative Literacy and Sports Supplementation Research for Improved Clinical Practice
by Alexander A. Huang and Samuel Y. Huang
Nutrients 2025, 17(15), 2463; https://doi.org/10.3390/nu17152463 - 28 Jul 2025
Viewed by 334
Abstract
In modern medical education, a robust understanding of statistics is essential for fostering critical thinking, informed clinical decision-making, and effective communication. This paper explores the synergistic value of early and continued statistical education for medical students and residents, particularly in relation to the [...] Read more.
In modern medical education, a robust understanding of statistics is essential for fostering critical thinking, informed clinical decision-making, and effective communication. This paper explores the synergistic value of early and continued statistical education for medical students and residents, particularly in relation to the expanding field of sports supplementation and its impact on athletic performance. Early exposure to statistical principles enhances students’ ability to interpret clinical research, avoid cognitive biases, and engage in evidence-based practice. Continued statistical learning throughout residency further refines these competencies, enabling more sophisticated analysis and application of emerging data. The paper also addresses key challenges in integrating statistics into medical curricula—such as limited curricular space, student disengagement, and resource constraints—and proposes solutions including interactive learning, case-based teaching, and the use of public datasets. A unique emphasis is placed on connecting statistical literacy to the interpretation of research in sports science, particularly regarding the efficacy, safety, and ethical considerations of sports supplements. By linking statistical education to a dynamic and relatable domain like sports performance, educators can not only enrich learning outcomes but also foster lasting interest and competence in quantitative reasoning. This integrated approach holds promise for producing more analytically proficient and clinically capable physicians. Full article
(This article belongs to the Special Issue The Role of Sports Supplements in Sport Performance)

Other

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7 pages, 451 KB  
Opinion
Use of Amino Acids as Supplements for Matching Nutrition, Training, and Rehabilitation—Focusing on Some Questions
by Francesco Saverio Dioaguardi
Nutrients 2025, 17(16), 2667; https://doi.org/10.3390/nu17162667 - 18 Aug 2025
Viewed by 495
Abstract
Exercise for improving physical performance or for rehabilitation and exercise for recovering from altered to normal efficiency of muscles, should be matched by adequacy of nutrition, thus supporting increased metabolic needs. Exercise triggers production of energy, and this is followed also by increased [...] Read more.
Exercise for improving physical performance or for rehabilitation and exercise for recovering from altered to normal efficiency of muscles, should be matched by adequacy of nutrition, thus supporting increased metabolic needs. Exercise triggers production of energy, and this is followed also by increased production of oxidant molecules, therefore, epigenetic adaptation in cells requires complex modifications, driven by an optimal balance between syntheses and autophagy, maintaining integrity and promoting increased efficiency of cells. Mitochondrial biogenesis, energy production, anti-oxidants systems, protein syntheses, and removal of inefficient structures are all subordinate to the sufficient availability of essential amino acids and they are indispensable to promote, activate, and maintain protein syntheses of all the structures, either contractile proteins or organelles, and related enzymatic systems on which physical efficiency is based. Increased needs or insufficient availability of essential amino acids in specific populations, due to peculiar changes in metabolism behaviors, as described in the training elderly, should be prevented and treated. Also, we are starting to understand the complexity of interactions among nutritional and physically driven activation of protein syntheses, and why only nutritional stimuli are poorly efficient in promoting muscle trophism even if essential amino acids remain indispensable for triggering syntheses. Moreover, the relationship between increased nutritional need and efficiency of immune system consequent to regular training should not be forgotten, particularly in rehabilitation programs for the elderly. Full article
(This article belongs to the Special Issue The Role of Sports Supplements in Sport Performance)
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