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Probiotics, Prebiotics, and Gut Health: New Frontiers in Treating Obesity, Diabetes, and Metabolic Disorders

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Diabetes".

Deadline for manuscript submissions: 25 March 2026 | Viewed by 184

Special Issue Editor


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Guest Editor
Department of Nutrition and Food Science, Wayne State University, Detroit, MI 48202, USA
Interests: nutraceutical and functional food; bioactive food components; probiotics; chronic diseases; type 2 diabetes; obesity

Special Issue Information

Dear Colleagues,

The objective of this Special Issue is to explore the intricate connection between the gut microbiome and metabolic health, specifically focusing on the therapeutic potential of probiotics and prebiotics. We aim to provide a comprehensive overview of how modulating gut microbiota can influence the prevention and management of a wide range of chronic metabolic diseases, including obesity, type-2 diabetes, and related conditions.

Topics of interest include, but are not limited to, the following:

  • The impact of dietary fibers and beneficial microbial strains on body weight regulation and fat metabolism.
  • The role of gut microbiota-derived metabolites (e.g., short-chain fatty acids) in influencing insulin sensitivity, glucose metabolism, and appetite regulation.
  • How gut barrier integrity, systemic inflammation, and immune function are modulated by prebiotics and probiotics.
  • Clinical studies and mechanistic research examining the efficacy of microbial interventions in managing obesity and diabetes.
  • The influence of the gut–brain axis on metabolic health and energy homeostasis.

The Special Issue seeks to synthesize recent advancements, highlighting promising clinical applications and identifying key areas for future research at the intersection of gut health and chronic disease.

Prof. Dr. Kequan Zhou
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • diabetes
  • prebiotics
  • probiotics
  • synbiotics
  • glycemic control
  • insulin resistance
  • inflammation
  • gut microbiome
  • gut barrier integrity
  • microbiota-targeted therapies

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Published Papers

This special issue is now open for submission.
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