Special Issue "Sarcopenia: From Diagnosis to Health Consequences and Nutritional Treatment"
Deadline for manuscript submissions: closed (31 July 2020).
Interests: body composition; sarcopenia; malnutrition; ectopic fat deposition
Interests: skeletal muscle; aging; exercise; mitochondria; obesity
With aging, a progressive decrease in skeletal muscle mass, which leads to a loss of strength and muscle function, is observed, defined by the term sarcopenia. This condition has a prevalence between 10% and 30%, depending on the setting and has recently been associated with ICD-10 code (M62.84). An insufficient protein dietary intake is one of the main causes leading to sarcopenia, and dietary recall by an expert dietician always has to be considered in order to decide which subjects are at risk for this condition.
The loss of muscle mass causes a reduction in strength, aerobic and functional capacity, associated with a high risk of worsening disability, mortality, and other unfavorable outcomes.
The European Working Group on Sarcopenia in Older People (EWGSOP2) recently revised the definition of sarcopenia, establishing three criteria necessary to diagnose sarcopenia: reduced muscle strength; reduction of the quantity or quality of the muscle; and reduction of physical performance.
In recent years, these measurements have become more available in impatient and outpatient clinics in order to screen elderly persons for this condition.
Sarcopenia is mainly observed in the elderly population, but it can also be observed in people over 50 due to particular conditions, such as prolonged bed rest or chronic diseases.
Sarcopenia manifests itself as chronic fatigue, muscle weakness, greater difficulty in lifting loads or performing normal daily activities.
Nutrition, since the middle ages, has played a pivotal role in the prevention of sarcopenia. Aminoacids and protein supplementation has been proposed as a strategy to counteract this phenomenon.
A lot of uncertainties still surround this condition—namely, in terms of (i) pathophysiology, (ii) adverse short- and long-term health effects, and (iii) nutritional management. In fact, no consensus exists on sarcopenia’s effects on health outcomes and optimum nutritional treatment strategies for this condition.
Therefore, we encourage investigators from different scientific backgrounds to submit to this Research Topic entitled “Sarcopenia: From Diagnosis to Health Consequences and Nutritional Treatment” that will accept manuscripts in the form of original research, systematic review, review, mini-review, and clinical trial articles providing a platform for the presentation of recent advances in our knowledge on sarcopenia.
In brief, three important clinical questions (but not limited to) that need to be addressed are:
- Which are the new insights in sarcopenia pathophysiology?
- What role is there for nutrition, different dietary patterns, and supplementation?
- What role is there for exercise and physical activity associated with nutritional intervention?
Prof. Dr. Andrea Rossi
Dr. Giovanna Distefano
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Muscle mass
- Muscle strength
- Physical performance