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Special Issue "Benefits of Dietary Phytochemicals"

A special issue of Nutrients (ISSN 2072-6643).

Deadline for manuscript submissions: 31 December 2019.

Special Issue Editor

Guest Editor
Prof. Jeremy J. Johnson

Univ Illinois, Coll Pharm, Dept Pharm Practice, 833 South Wood St Room 164, Chicago, IL 60612, USA
Website | E-Mail
Interests: Dietary supplements; phytochemicals; cancer; translational research; pharmacognosy

Special Issue Information

Dear Colleagues,

This Special Issue will focus on selected plants and phytochemicals therein to describe the role of dietary phytochemicals that modify cell signaling pathways. Plants are well known to generate a variety of phytochemicals that possess unique physical and chemical properties.  The attributes of each phytochemical are responsible for producing unique chemical interactions with traditional and novel disease targets. A layer of complexity includes the use of combinations of phytochemicals present in selected extracts and how these phytochemicals generative a comprehensive pharmacological response.

More specifically, this Special Issue will focus on understanding how dietary phytochemicals, isolated and present in unique combinations, can be used for generating positive benefits with respect to overall health.

Prof. Jeremy J. Johnson
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • polyphenols
  • plants
  • phytochemicals
  • bioactive compounds
  • natural products
  • functional foods
  • medicinal products
  • disease prevention
  • inflammation
  • oxidative stress
  • vascular dysfunction
  • aging
  • mitochondrial functionality
  • apoptosis

Published Papers (1 paper)

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Research

Open AccessArticle
Sesame Lignans Suppress Age-Related Cognitive Decline in Senescence-Accelerated Mice
Nutrients 2019, 11(7), 1582; https://doi.org/10.3390/nu11071582
Received: 31 May 2019 / Revised: 29 June 2019 / Accepted: 9 July 2019 / Published: 12 July 2019
PDF Full-text (1559 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
Sesame lignans, which are biologically active compounds present in sesame seeds and oil, are known to have neuroprotective effects in several models of brain dysfunction. However, the effects of sesame lignans on age-related brain dysfunction are not clear and were thus investigated in [...] Read more.
Sesame lignans, which are biologically active compounds present in sesame seeds and oil, are known to have neuroprotective effects in several models of brain dysfunction. However, the effects of sesame lignans on age-related brain dysfunction are not clear and were thus investigated in the present study using a senescence-accelerated mouse (SAMP10). Two-month-old male SAMP10 mice were administrated a basal diet with 0% or 0.05% sesame lignans for two months, or with 0%, 0.02%, or 0.05% sesame lignans for 10 months and subjected to step-through passive avoidance tasks and forced swim tests. Reactive carbonyl species (RCs) were evaluated as markers of oxidative stress using a recently developed comprehensive analytical method. Both learning time in passive avoidance tasks and immobile time in forced swim tests became longer with aging (p < 0.05). However, the administration of sesame lignans significantly ameliorated age-related effects in both tests (p < 0.05). Age-related increases in RCs such as 4-hydroxy-2-nonenal in the cerebral cortex and liver were reduced in mice fed sesame lignans. These results suggest that sesame lignans can prevent age-related brain dysfunction via anti-oxidative activity. Full article
(This article belongs to the Special Issue Benefits of Dietary Phytochemicals)
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

1. Jeremy J. Johnson
affiliation: Univ Illinois, Coll Pharm, Dept Pharm Practice, 833 South Wood St Room 164, Chicago, IL 60612, USA
topic: Maternal Flavonoids Intake Reverts Depression-Like Behaviour in Rat Female
2. Satomi Shimoyoshi
affiliation: Institute for Health Care Science, Suntory Wellness Limited, Kyoto 619-0284, Japan
topic: Sesame Lignans Suppress Age-Related Cognitive Decline in Senescence-Accelerated Mice
3. Miguel Navarro-Alarcón
affiliation: Department of Nutrition and Food Science, School of Pharmacy, University of Granada, E-18071, Granada, Spain
topic: Antihypercholesterolaemic effect of polyphenol-rich carob fibre
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