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Nutrients
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Dietary Protein and Surgery Patient
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Dietary Protein and Surgery Patient

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Proteins and Amino Acids".

Deadline for manuscript submissions: closed (20 March 2023) | Viewed by 8922

Special Issue Editor

Dr. Igor Sukhotnik

E-Mail Website
Guest Editor
Laboratory of Intestinal Adaptation and Recovery, Department of Paediatric Surgery, Dana-Dwek Children’s Hospital, Tel Aviv Sourasky Medical Center, 6 Weizmann st, Tel Aviv 6423906, Israel
Interests: general surgery; pediatric surgery; intestinal failure; short bowel syndrome; nutrition; metabolism
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

You are invited to submit proposals for manuscripts that fit the objectives of this Special Issue, entitled “Dietary Protein and Surgical Patient”.

Early oral feeding is crucial in determining surgical outcomes, especially for those undergoing gastrointestinal (GI) surgery. Avoidance of any nutritional therapy and subsequent malnutrition bears the risk of underfeeding during the postoperative course after major surgery and is considered a risk factor for postoperative complications. On the other hand, malabsorption and malnutrition are common problems encountered in the management of GI surgical conditions, especially among patients who undergo GI surgeries for malignancies.

Normal protein metabolism is crucial in surgical patients. There is a paucity of data regarding targeted daily protein intake and its effect on fat-free mass. Sarcopenia is a common complication that persists up to two years post-major surgery.  Patients with sarcopenia were three times more likely to experience postoperative complications after GI surgery, twice as likely to be readmitted, and have a poorer quality of life. Nutritional restoration of protein remains a conundrum among upper GI surgical patients, especially among those after GI surgery.

In this issue, we look at the role of dietary protein in the pre- and postoperative management of surgical patients.

Dr. Igor Sukhotnik
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • dietary protein
  • surgery
  • patient
  • protein metabolism
  • postoperative complications
  • protein deficiency
  • malnutrition

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Published Papers (3 papers)

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Research

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13 pages, 926 KiB  
Article
Adherence to and Efficacy of the Nutritional Intervention in Multimodal Prehabilitation in Colorectal and Esophageal Cancer Patients
by Sabien H. van Exter, Luuk D. Drager, Monique J. M. D. van Asseldonk, Dieuwke Strijker, Nina D. van der Schoot, Baukje van den Heuvel, Sjors Verlaan and Manon G. A. van den Berg
Nutrients 2023, 15(9), 2133; https://doi.org/10.3390/nu15092133 - 28 Apr 2023
Cited by 7 | Viewed by 3088
Abstract
Multimodal prehabilitation programs to improve physical fitness before surgery often include nutritional interventions. This study evaluates the efficacy of and adherence to a nutritional intervention among colorectal and esophageal cancer patients undergoing the multimodal Fit4Surgery prehabilitation program. The intervention aims to achieve an [...] Read more.
Multimodal prehabilitation programs to improve physical fitness before surgery often include nutritional interventions. This study evaluates the efficacy of and adherence to a nutritional intervention among colorectal and esophageal cancer patients undergoing the multimodal Fit4Surgery prehabilitation program. The intervention aims to achieve an intake of ≥1.5 g of protein/kg body weight (BW) per day through dietary advice and daily nutritional supplementation (30 g whey protein). This study shows 56.3% of patients met this goal after prehabilitation. Mean daily protein intake significantly increased from 1.20 ± 0.39 g/kg BW at baseline to 1.61 ± 0.41 g/kg BW after prehabilitation (p < 0.001), with the main increase during the evening snack. BW, BMI, 5-CST, and protein intake at baseline were associated with adherence to the nutritional intervention. These outcomes suggest that dietary counseling and protein supplementation can significantly improve protein intake in different patient groups undergoing a multimodal prehabilitation program. Full article
(This article belongs to the Special Issue Dietary Protein and Surgery Patient)
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Review

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20 pages, 794 KiB  
Review
Clearing Steatosis Prior to Liver Surgery for Colorectal Metastasis: A Narrative Review and Case Illustration
by Andrea Peloso, Matthieu Tihy, Beat Moeckli, Laura Rubbia-Brandt and Christian Toso
Nutrients 2022, 14(24), 5340; https://doi.org/10.3390/nu14245340 - 15 Dec 2022
Cited by 2 | Viewed by 2896
Abstract
Over recent years, non-alcoholic fatty liver disease (NAFLD) has become the most common liver disorder in the developed world, accounting for 20% to 46% of liver abnormalities. Steatosis is the hallmark of NAFLD and is recognized as an important risk factor for complication [...] Read more.
Over recent years, non-alcoholic fatty liver disease (NAFLD) has become the most common liver disorder in the developed world, accounting for 20% to 46% of liver abnormalities. Steatosis is the hallmark of NAFLD and is recognized as an important risk factor for complication and death after general surgery, even more so after liver resection. Similarly, liver steatosis also impacts the safety of live liver donation and transplantation. We aim to review surgical outcomes after liver resection for colorectal metastases in patients with steatosis and discuss the most common pre-operative strategies to reduce steatosis. Finally, as illustration, we report the favorable effect of a low-caloric, hyper-protein diet during a two-stage liver resection for colorectal metastases in a patient with severe steatosis. Full article
(This article belongs to the Special Issue Dietary Protein and Surgery Patient)
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Other

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11 pages, 503 KiB  
Brief Report
Impact of Dietary Protein on the Management of Pediatric Short Bowel Syndrome
by Igor Sukhotnik, Reut Levi and Hadar Moran-Lev
Nutrients 2023, 15(13), 2826; https://doi.org/10.3390/nu15132826 - 21 Jun 2023
Cited by 5 | Viewed by 2365
Abstract
Essential amino acids (AAs) play a key role in stimulating intestinal adaptation after massive small gut resection. The nutritional effect of dietary amino acids during intestinal regrowth has received considerable attention in recent years. This review explores the significance of dietary amino acids [...] Read more.
Essential amino acids (AAs) play a key role in stimulating intestinal adaptation after massive small gut resection. The nutritional effect of dietary amino acids during intestinal regrowth has received considerable attention in recent years. This review explores the significance of dietary amino acids in the nutritional management of infants and children with intestinal failure and short bowel syndrome (SBS) as reported in the medical literature over the last three decades. A literature search was conducted using electronic databases. Breast milk emerged as the first-line enteral regimen recommended for infants with SBS. Hydrolyzed formulas (HFs) or amino acid formulas (AAFs) are recommended when breast milk is not available or if the infant cannot tolerate whole protein milk. The superiority of AAFs over HFs has never been demonstrated. Although glutamine (GLN) is the main fuel for enterocytes, GLN supplementation in infants with SBS showed no difference in the child’s dependence upon parenteral nutrition (PN). Circulating citrulline is considered a major determinant of survival and nutritional prognosis of SBS patients. Early enteral nutrition and dietary supplementation of AAs following bowel resection in children are essential for the development of intestinal adaptation, thereby eliminating the need for PN. Full article
(This article belongs to the Special Issue Dietary Protein and Surgery Patient)
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