Diet and Prevention of Alzheimer’s Disease or Age-Related Cognitive Decline

Dear Colleagues,

This Research Topic’s primary goal is to increase our knowledge of the role of diet in the prevention of age-related cognitive decline, with a particular focus on Alzheimer’s Disease neuropathology, by exploring underpinning mechanisms to characterize dietary pattern and lifestyle factors able to counteract the dreadful consequences of aging. Furthermore, we want to give space to innovative research on the biological mechanisms of nutrients for therapeutic use, not only for cognitive disorders but also for the management of AD-related behavioral disturbance.

Finally, because neuropathological changes occur decades before the onset of clinical manifestation of cognitive disorders, we encourage authors to describe the impact of diet in terms of lifespan perspective. Our overarching aim is to build a comprehensive framework where theory, diverse methodological analyses, perspectives and new technological advancements could converge.

This Research Topic aims to stimulate research and give a multi-layered pyramidal perspective on diet, covering various critical points (in particular, whether the Mediterranean Diet still feasible in a fast-evolving society, and whether current “healthy foods” are still valid in the prevention of AD pathology). We encourage authors to explore the topic under the lens of a gender- and ethnicity-oriented personalized nutrition.

We welcome reviews (systematic and narrative) and mini reviews, original research papers (in vitro and in vivo), perspective papers, hypothesis and theory papers, methods papers and case reports.

Dr. Vincenza Frisardi
Dr. Emanuele Rocco Villani
Dr. Andrea Fabbo
Guest Editors

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