Mediterranean Diet in Chronic Disease Prevention and Aging

Dear Colleagues,

The Mediterranean dietary pattern has been shown to protect against cardiometabolic diseases and reduce mortality in numerous studies and meta-analyses. There are also multiple investigations that have examined its protective effects against other types of chronic diseases and various intermediate health–disease phenotypes. However, further studies are needed that incorporate the latest advances in precision nutrition using various omic markers (genomics, epigenomics, metabolomics, metagenomics, transcriptomics and proteomics), as well as new statistical analysis methodologies based on advanced computing. Further research is also needed on how the Mediterranean diet relates to new aging biomarkers and how this modulation affects health outcomes of interest. Fundamentally, studies on epigenetic-based aging biomarkers—the most established (several generations of “methylation clocks”)—are necessary, but it is also highly novel to analyze new aging biomarkers based on other omics, digital devices, functional data, or biochemical and clinical data. It additionally becomes of great interest to identify new factors associated with higher or lower adherence to the Mediterranean diet that can be useful in intervention studies or health education.

Prof. Dr. Dolores Corella
Guest Editor

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