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The Gut Microbiome: Mechanisms and Therapies in Communicable and Non-Communicable Diseases

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Public Health".

Deadline for manuscript submissions: 15 July 2026 | Viewed by 37

Special Issue Editor


E-Mail Website
Guest Editor
Department of Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Interests: gut microbiota; human disease; gene expression; biomarkers

Special Issue Information

Dear Colleagues,

The gut microbiome plays a key role in human health, informing immune system development and metabolism. Reflecting this, a wide spectrum of human diseases has been linked to disruption of the delicate gut microbiome ecosystem. In communicable diseases, for instance, the microbiome has been found to influence susceptibility to infection, modulate vaccine responses, and interact with microbial exposure pathogens. In non-communicable diseases—such as diabetes, cardiovascular disease, cancer, and neurodegenerative disorders—dysbiosis can serve as an accurate biomarker of risk. In some cases, it is also a driver of disease. In recent years, mechanistic studies have revealed how microbial metabolites, signaling pathways, and host–microbe interactions contribute to disease initiation, progression, and recovery across both infectious and chronic conditions.

This Special Issue invites original research that advances our understanding of the microbiome in communicable and non-communicable diseases, as well as comprehensive reviews. We welcome studies that (I) address targeted therapies, such as diet, prebiotics, probiotics, postbiotics, synbiotics, and microbial-derived small molecules; (II) introduce innovative analytical or quantitative multi-omics methods; or (III) explore translational and precision microbiome therapeutic strategies. Overall, this Collection aims to integrate basic, clinical, and translational perspectives toward augmenting our collective understanding of microbiome-informed strategies for prevention and treatment across the disease spectrum.

Dr. Tatiana Marquez-Lago
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • microbiome
  • multi-omics
  • translational
  • communicable diseases
  • non-communicable diseases

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Published Papers

This special issue is now open for submission.
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