Effects of Genetic, Nutritional and Inflammatory Factors in Gastrointestinal Cancer
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutritional Immunology".
Deadline for manuscript submissions: 25 January 2026 | Viewed by 2
Special Issue Editor
2. Diet, Microbiota, and Health Group, Instituto de Investigación Sanitaria del Principado de Asturias (DIMISA, Health Research Institute of Asturias), 33004 Oviedo, Spain
Interests: microbiome; probiotics; prebiotics; xenobiotics; polyphenols; fibers; colorectal cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Gastrointestinal (GI) cancers—including colorectal, gastric, pancreatic, esophageal, and hepatobiliary malignancies—represent a major global health burden, with rising incidence and mortality rates in many regions. Despite advances in screening, diagnostics, and therapy, the prognosis for many GI cancers remains poor, largely due to their complex and multifactorial etiology. A growing body of research highlights the critical roles played by genetic, nutritional, and inflammatory factors in the initiation, progression, and therapeutic response of GI cancers.
This Special Issue seeks to bring together cutting-edge research and comprehensive reviews that explore the interplay between inherited and acquired genetic alterations, dietary exposures, and chronic inflammation in gastrointestinal tumorigenesis. We aim to highlight mechanistic studies that elucidate how specific gene–environment interactions and inflammatory signaling pathways drive malignant transformation and influence disease course. Contributions addressing the impact of the gut microbiome, nutrient-gene interactions, and inflammation-associated epigenetic modifications are particularly encouraged.
By fostering an interdisciplinary dialog between genetics, nutrition science, oncology, and immunology, this Special Issue aims to advance our understanding of GI cancer biology and promote the development of personalized prevention and treatment strategies.
Dr. Sonia González
Guest Editor
Manuscript Submission Information
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Keywords
- microbiome
- gastrointestinal cancer
- polyphenol
- fibers
- inflammation
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