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High-Fat Diet, Obesity, and Behavioral Health

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Obesity".

Deadline for manuscript submissions: closed (15 April 2024) | Viewed by 1079

Special Issue Editors


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Guest Editor
Developmental and Behavioral Pediatrics, First Department of Pediatrics, School of Medicine, National and Kapodistrian University of Athens, “Aghia Sophia” Children’s Hospital, 11527 Athens, Greece
Interests: stress; HPA-axis; autonomic nervous system; stress-related disorders; PTSD; ADHD; autism spectrum disorders; neurodevelopmental disorders; obesity; psychoneuroendocrinology
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Professor of Nutrition and Eating Behavior, Harokopio University, Athens, Greece
Interests: eating behavior; nutrition assessment; obesity; metabolic syndrome; eating disorders
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
First Department of Pediatrics, National and Kapodistrian, University of Athens Medical School, “Aghia Sophia” Children’s Hospital, 11527 Athens, Greece
Interests: diabetes; childhood obesity; insulin resistance; glucose metabolism; clinical endocrinology; human nutrition; obesity; diabetes mellitus; metabolic syndrome
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

High-fat diets and obesity have been reciprocally related to cognition and behavior. Both experimental and clinical studies from prenatal life and through the lifespan have investigated the effects of a high-fat diet/obesity on cognitive function and behavioral parameters. Conversely, cognitive and executive functions of an individual, as well as behavioral features can lead to increased or specific eating conditions and obesity. Cardiometabolic and mental health adverse outcomes are long-term implications of the inter-relations between a high-fat diet/obesity and cognitive/behavioral health.

Considering the success of the previous Special Issue entitled "High-Fat Diet, Obesity, and Behavioral Health", we are pleased to announce that we are launching a second Special Issue on this topic.

This Special Issue welcomes original research and review articles, with clinical, experimental and epidemiological content concerning the relations between a high-fat diet and/or obesity, and cognitive and behavioral health, with a particular focus on:

  • The effects of prenatal food/nutrition alterations and/or obesity on brain function and behavior of the offspring;
  • The effects of diet and obesity on cognitive and behavioral measures in adults and children;
  • The relations of cognition-related conditions (e.g., intellectual disability, executive dysfunction in ADHD and other mental health conditions, cognitive decline, etc.) with nutrition and obesity;
  • The relations between behavioral problems and disorders, including stress-related conditions with nutrition and obesity;
  • Behavioral interventions for obesity;
  • Nutritional interventions for cognitive and/or behavioral conditions;
  • Mechanisms of action, pathways and molecules mediating the relations between diet, obesity, cognition and behavior, including methods such as proteomics, metabolomics, etc.;
  • Genetics linking diet, obesity, cognition and behavior;
  • Development of tools, methods and strategies targeting obesity through behavioral techniques.

Prof. Dr. Panagiota Pervanidou
Prof. Dr. Mary Yannakoulia
Prof. Dr. Christina Kanaka-Gantenbein
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • obesity
  • high-fat diet
  • metabolism
  • cognition
  • behavior
  • stress
  • mental health

Published Papers (1 paper)

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Research

16 pages, 309 KiB  
Article
Functional Gastrointestinal Symptoms in Children with Autism and ADHD: Profiles of Hair and Salivary Cortisol, Serum Leptin Concentrations and Externalizing/Internalizing Problems
by Andreas Petropoulos, Sophia Anesiadou, Maria Michou, Aikaterini Lymperatou, Eleftheria Roma, George Chrousos and Panagiota Pervanidou
Nutrients 2024, 16(10), 1538; https://doi.org/10.3390/nu16101538 - 20 May 2024
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Abstract
Background: Functional Gastrointestinal Disorders (FGIDs) present a higher prevalence in individuals with Neurodevelopmental Disorders (NDDs). The Stress System and the Gut–Brain axis (GBA) may mediate these relations. We aimed to assess the prevalence and profile of FGIDs in a clinical sample of children [...] Read more.
Background: Functional Gastrointestinal Disorders (FGIDs) present a higher prevalence in individuals with Neurodevelopmental Disorders (NDDs). The Stress System and the Gut–Brain axis (GBA) may mediate these relations. We aimed to assess the prevalence and profile of FGIDs in a clinical sample of children with Autism Spectrum Disorder (ASD) and Attention Deficit/Hyperactivity Disorder (ADHD) compared to typically developing children (TD) as well as to investigate possible relations between stress-related biomarkers and internalizing/externalizing problems in children with NDDS. Methods: In total, 120 children, aged between 4 and 12 years old, formed three groups (N = 40, each): ADHD, ASD and TD. Salivary cortisol, hair cortisol and serum leptin were measured. Results: The ASD group had more FGID problems than the TD group (p = 0.001). The ADHD and ASD groups had higher total internalizing/externalizing problems than the TD group (p < 0.0001, p < 0.0001, p = 0.005, respectively). Children with FGIDs showed more total, internalizing and externalizing problems compared to children without FGIDs (p < 0.0001, p < 0.0001, p = 0.041, respectively). The ADHD group showed lower AUCg values (p < 0.0001), while the hair cortisol was higher for the TD group (p < 0.0001). Conclusion: In conclusion, children with NDDs had more FGID symptoms and present higher internalizing and externalizing problems. Children with ADHD and FGIDs had more internalizing problems compared to those without FGIDs. No differences in stress-related biomarkers were shown to differentiate children with NDDs with and without FGIDs. Future prospective studies including a greater number of children may elucidate the biological pathways linking these comorbidities. Full article
(This article belongs to the Special Issue High-Fat Diet, Obesity, and Behavioral Health)
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