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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Progress in Polymeric Drug Delivery Systems
edited by Barbara Zawidlak-Węgrzyńska, and
submission deadline 31 Jan 2027 | Viewed by 190 | Submission Open
Keywords: biomaterials; biocompatibility of polymer systems; (bio)degradable and synthetic polymers in medical applications; degradation of biomaterials, stimuli-responsive polymers (e.g., pH-, enzyme-, temperature-, or light-sensitive systems); AI-driven design and optimization of drug delivery systems; sustainability in polymer synthesis, including eco-friendly and bio-based materials
(This special issue belongs to the Section Medicinal Chemistry)
Recent Advances of Nanomaterials in Electrochemistry
edited by Najeeb Lashari
submission deadline 31 Jan 2027 | Viewed by 190 | Submission Open
Keywords: nanomaterials; electrochemistry; nanostructured electrodes; electrocatalysis; energy storage; batteries; supercapacitors; electrochemical sensors; nanocomposites; two-dimensional materials; transition metal oxides; carbon nanomaterials; conductive polymers; interface engineering; charge transport; photoelectrochemistry; green energy technologies; surface chemistry; nano-electrocatalysts; advanced functional materials
(This special issue belongs to the Section Nanochemistry)
Advanced Research on Computer-Aided Drug Design
edited by , and Özgecan Kayalar
submission deadline 31 Jan 2027 | Viewed by 186 | Submission Open
Keywords: computer-aided drug design; structure-based drug design; molecular docking; molecular dynamics simulations; virtual screening; hit-to-lead optimization; binding free energy; ADMET prediction; machine learning in drug discovery; protein–ligand interactions; mutation-driven drug resistance; computational medicinal chemistry
(This special issue belongs to the Section Medicinal Chemistry)
Carbon-Based Nanomaterials and Their Applications
edited by Naveen Kumar Reddy Bogireddy, Juan Horacio Pacheco-Sánchez and Claudia Muro
submission deadline 31 Jan 2027 | Viewed by 182 | Submission Open
Keywords: carbon nanomaterials; graphene; carbon nanotubes; fullerenes; graphyne; diamond-like carbon; carbon dots; molecular dynamics; density functional theory; Monte Carlo simulation; multiscale modeling; catalysis; photocatalysis; adsorption; CO2 capture; hydrogen storage; energy storage; supercapacitors; wastewater treatment; environmental remediation; sustainable materials; nanocomposites; gas separation; porous carbon materials; green synthesis
(This special issue belongs to the Section Materials Chemistry)
Phenolic Compounds from Foods: Extraction, Characterization, and Biological Activity submission deadline 31 Jan 2027 | Viewed by 177 | Submission Open
Keywords: phenolic compounds; food extracts; extraction techniques; chemical characterization; biological activity; antioxidant properties
(This special issue belongs to the Section Food Chemistry)
Chemical Characterisation and Biological Evaluation of Bioactive Extracts and Functional Ingredients from Agro-Food By-Products
edited by Anca Becze
submission deadline 31 Jan 2027 | Viewed by 168 | Submission Open
Keywords: agro-food by-products; compositional profiling; bioactive compounds; extraction and valorisation; functional food ingredients; antioxidant and antimicrobial activity
(This special issue belongs to the Section Food Chemistry)
Biochar in Environmental Chemistry: Mechanisms, Reactivity, and Applications submission deadline 31 Jan 2027 | Viewed by 165 | Submission Open
Keywords: biochar; environmental chemistry; sorption mechanisms; reactivity; pollutant transformation; advanced oxidation processes; carbon sequestration; soil remediation; water treatment
(This special issue belongs to the Section Green Chemistry)
Research Progress on Functional Lipids and Their Applications in Health Food Systems—2nd Edition
edited by
submission deadline 31 Jan 2027 | Viewed by 158 | Submission Open
Keywords: lipid crystallization; lipid oxidation; enzymatic lipid modification; processing; health benefits; structured emulsions; lipid emulsions; lipid capsules
(This special issue belongs to the Section Food Chemistry)
Biopolymers for Drug Delivery Systems, 2nd Edition
edited by and Petra Arany
submission deadline 31 Jan 2027 | Viewed by 156 | Submission Open
Keywords: drug delivery systems; biopolymers; personalized medication; nanoparticle; hydrogel; 3D printing
(This special issue belongs to the Section Medicinal Chemistry)
Aromatic Heterocyclic Compounds: From Synthesis to Biological Activities Research submission deadline 31 Jan 2027 | Viewed by 150 | Submission Open
Keywords: aromatic heterocycles; organic synthesis; medicinal chemistry; bioactive scaffolds; SAR; synthetic methodologies
(This special issue belongs to the Section Organic Chemistry)
Advanced Metal-Based Drug Formulations in Cancer Treatment
edited by Sanja A. Mijatović and
submission deadline 31 Jan 2027 | Viewed by 149 | Submission Open
Keywords: metal-based drugs; chemotherapy; cancer; tumor microenvironment; hybrid molecules; drug design; anticancer activity; drug delivery; tumor resistance
(This special issue belongs to the Section Medicinal Chemistry)
Research on 1,8-Naphthalimide Scaffold: Present and Future
edited by
submission deadline 31 Jan 2027 | Viewed by 140 | Submission Open
Keywords: 1,8-naphthalimide; derivative of 1,8-naphthalimide; synthesis of 1,8-naphthalimide; spectroscopic properties of 1,8-naphthalimide; fluorescent sensors; biosensors; sensing mechanisms; photophysical properties; crystal structures, computation, fluorescent dyes, cell imaging, textile dyes; OLEDs; electroluminescent materials; liquid crystal displays; ligand; intercalators; biomedical applications (analgesics); anti-depressants; anti-tumor agents; antiprotozoals; antirheumatics; antimicrobials; antivirals; anti-inflammatory agents; enzyme inhibitors
(This special issue belongs to the Section Organic Chemistry)
Ionic Liquids and Deep Eutectic Solvents for Pharmaceutical Analysis
edited by and Branislava Teofilović
submission deadline 31 Jan 2027 | Viewed by 140 | Submission Open
Keywords: ionic liquids; deep eutectic solvents; physicochemical analysis; green extraction and separation; phytochemicals; pharmaceutical analysis; chromatographic analysis; active pharmaceutical ingredients
(This special issue belongs to the Section Analytical Chemistry)
New Insights into Maillard Reaction
edited by Junjian Miao and
submission deadline 31 Jan 2027 | Viewed by 135 | Submission Open
Keywords: Maillard reaction; advanced glycation end-products (AGEs); food chemistry; flavor formation; non-enzymatic browning; acrylamide mitigation; reaction kinetics; nutritional impact; bioactive compounds; food processing
(This special issue belongs to the Section Flavours and Fragrances)
Emerging Natural Antioxidants for Food Storage and Functional Food Innovation submission deadline 31 Jan 2027 | Viewed by 134 | Submission Open
Keywords: natural antioxidants; food storage; functional food; food safety; shelf life
(This special issue belongs to the Section Food Chemistry)
Biologically-Derived Nanomaterials: Synthesis, Functionalization and Applications in Environmental and Circular Technologies
edited by , and
submission deadline 31 Jan 2027 | Viewed by 132 | Submission Open
Keywords: green synthesis; nanomaterials; biomass-derived materials; water treatment; environmental remediation; circular economy; photocatalysis; waste valorisation
(This special issue belongs to the Section Nanochemistry)
Synthesis, Mechanism and Applications of Fluorinated Compounds
edited by
submission deadline 31 Jan 2027 | Viewed by 117 | Submission Open
Keywords: green chemistry; heterocycles; organofluorides; PFAS; per- and polyfluoroalkyl substances
(This special issue belongs to the Section Organic Chemistry)
Biomaterials and Bioactive Systems: From Synthesis to Biomedical Applications
edited by Pedro M.G. Nicolau, and
submission deadline 31 Jan 2027 | Viewed by 116 | Submission Open
Keywords: biomaterials; bioactive systems; tissue engineering; drug delivery; biomedical applications
(This special issue belongs to the Section Cross-Field Chemistry)
Research Advances in Rotational Spectroscopy: From Structures to Large Amplitude Motions of Molecules
edited by
submission deadline 31 Jan 2027 | Viewed by 115 | Submission Open
Keywords: rotational spectroscopy; microwave spectroscopy; large amplitude motion; structure determination; non-covalent interaction; nuclear quadrupole coupling
(This special issue belongs to the Section Molecular Structure)
Advances on Plant Extracts: Antioxidant and Anticancer Properties
edited by
submission deadline 31 Jan 2027 | Viewed by 102 | Submission Open
Keywords: plant extracts; antioxidants; free radicals; oxidative stress; melanin biopolymers; cancer; UV-Vis spectrophotometry; EPR spectroscopy
(This special issue belongs to the Section Natural Products Chemistry)
Advances in Conductive Composite Materials
edited by , and Ilaria Improta
submission deadline 31 Jan 2027 | Viewed by 89 | Submission Open
Keywords: conductive composite materials; polymer nanocomposites; conductive fillers; carbon nanotubes (CNTs); graphene; MXenes; hybrid nanocomposites; smart textiles; interfacial engineering; structure–property relationships
(This special issue belongs to the Section Materials Chemistry)
Advances in Terpenes and Terpene Derivatives
edited by Xin Hua, and
submission deadline 31 Jan 2027 | Viewed by 87 | Submission Open
Keywords: terpenes; terpenoids; natural products; biosynthesis; synthetic biology; enzyme characterization; metabolic engineering; structural elucidation; bioactivity; chemical synthesis
(This special issue belongs to the Section Natural Products Chemistry)
Natural Products: Extraction, Analysis and Biological Activities: 2nd Edition
edited by
submission deadline 31 Jan 2027 | Viewed by 85 | Submission Open
Keywords: plant products; secondary metabolites; extraction; analysis; quality of natural products; biological activity; health-promoting properties; agricultural waste
(This special issue belongs to the Section Natural Products Chemistry)
Application of Advanced Materials in Green Catalysis
edited by Francesca Coccia
submission deadline 31 Jan 2027 | Viewed by 84 | Submission Open
Keywords: green catalysis; advanced materials; catalytic materials; environmental remediation; renewable resources; sustainable synthesis; biomass valorization
(This special issue belongs to the Section Materials Chemistry)
Innovations in Catalysts for Hydrogen Evolution Reactions
edited by Socorro Oros-Ruiz
submission deadline 31 Jan 2027 | Viewed by 84 | Submission Open
Keywords: hydrogen evolution reaction; electrocatalysis; green hydrogen; metal nanoparticles; carbon-supported catalysis; metal organic frameworks (MOFs); nanomaterials; heterostructures; water splitting; photoreforming; artificial photosynthesis; catalysts design
(This special issue belongs to the Section Materials Chemistry)
Biotechnological Synthesis, Molecular Characterization, and Formulation of Next-Generation Cosmetic Actives
edited by , Andreea Loredana Vonica-Tincu and Daniela Lucia Muntean
submission deadline 31 Jan 2027 | Viewed by 79 | Submission Open
Keywords: biocosmetics; next-generation cosmeceuticals; microbial fermentation; skin delivery systems; green formulation chemistry; bioactive peptides; sustainable ingredients; encapsulation
(This special issue belongs to the Section Applied Chemistry)
Natural Products in Anticancer Activity: 3rd Edition
edited by Luciana Scotti
submission deadline 31 Jan 2027 | Viewed by 62 | Submission Open
Keywords: natural products; anticancer; drug; nature; molecule
(This special issue belongs to the Section Natural Products Chemistry)
Carbon-Based Electrochemical Materials: Advances and Applications
edited by
submission deadline 31 Jan 2027 | Viewed by 44 | Submission Open
Keywords: electrocatalysis; nanomaterials; HER; OER; ORR; CO2 reduction; fuel cells; single-atom catalysts; MXenes; nanostructured catalysts; sustainable energy; electrochemical conversion
(This special issue belongs to the Section Electrochemistry)
Functional Heterocycles: Sustainable Synthesis and Biological Applications submission deadline 31 Jan 2027 | Viewed by 42 | Submission Open
Keywords: heterocyclic compounds; sustainable synthesis; catalytic transformations; asymmetric synthesis; medicinal chemistry; biologically active compounds; functional organic materials; fluorescent probes; green chemistry
(This special issue belongs to the Section Organic Chemistry)
Molecular Structure and Dynamics: Spectroscopy, Calorimetry, and Applications submission deadline 31 Jan 2027 | Viewed by 41 | Submission Open
Keywords: molecular structure; molecular dynamics; spectroscopy; calorimetry; intermolecular interactions; ligand-protein interactions; antioxidant protein
(This special issue belongs to the Section Physical Chemistry)
Bioactive Compounds in Plants: Extraction and Application, 2nd Edition submission deadline 31 Jan 2027 | Viewed by 33 | Submission Open
Keywords: bioactive molecules; sustainable extraction; isolation and elucidation; biological activities; mechanisms of action; food science; nanotechnology; delivery systems; bioavailability; controlled release
(This special issue belongs to the Section Natural Products Chemistry)
Recent Advances in Mass Spectrometry-Based Analysis and Bioanalysis submission deadline 31 Jan 2027 | Viewed by 25 | Submission Open
Keywords: mass spectrometry; chromatography; bioanalysis; metabolomics; proteomics
(This special issue belongs to the Section Analytical Chemistry)
Photothermal Materials for Drug Delivery
edited by
submission deadline 4 Feb 2027 | Viewed by 111 | Submission Open
Keywords: photothermal materials; drug delivery; disease therapy
(This special issue belongs to the Section Materials Chemistry)
Natural Antioxidants: Applications in Foods, Medicine and Cosmetics submission deadline 10 Feb 2027 | Viewed by 146 | Submission Open
Keywords: natural antioxidants; bioactive compounds; plant extracts; polyphenols; phytochemicals; antioxidant potential
(This special issue belongs to the Section Natural Products Chemistry)
Bioactive Natural Product Compounds in Cancer Prevention and Therapy submission deadline 15 Feb 2027 | 1 articles | Viewed by 1099 | Submission Open
Keywords: natural product; cytotoxic; bioactivity mechanism; cancer; drug discovery; drug delivery; chemoprevention
(This special issue belongs to the Section Natural Products Chemistry)
Natural Compounds for Disease and Health, 4th Edition submission deadline 15 Feb 2027 | 1 articles | Viewed by 971 | Submission Open
Keywords: natural products; phytochemistry; structure–activity relationship; mechanisms of action; anti-aging; cancer; cardiovascular diseases; digestive diseases; endocrine disorders; immune diseases; infections; inflammation; liver diseases; metabolic diseases; musculoskeletal diseases; neurodegenerative diseases; pain; psychiatric diseases; renal diseases; respiratory diseases
(This special issue belongs to the Section Natural Products Chemistry)
Recent Trends in Pharmaceutical Analysis for Drug Development, Therapeutic Monitoring and Biomarker Discovery submission deadline 15 Feb 2027 | Viewed by 500 | Submission Open
Keywords: pharmaceutical analysis; bioanalysis; drug development; therapeutic monitoring; biomarker discovery; omics; toxicological analysis
(This special issue belongs to the Section Medicinal Chemistry)
Enzyme Inhibitors: Structural Characterization and Applications submission deadline 15 Feb 2027 | Viewed by 142 | Submission Open
Keywords: enzyme inhibitors; DFT; molecular docking; molecular dynamics; structure–activity relationship
(This special issue belongs to the Section Medicinal Chemistry)
Natural Bioactives and Functional Ingredients in Foods
edited by
submission deadline 16 Feb 2027 | 7 articles | Viewed by 5562 | Submission Open
Keywords: natural bioactive compounds; functional food ingredients; health-promoting foods; nutraceuticals; food innovation
(This special issue belongs to the Section Food Chemistry)
Photoelectrochemical Properties of Nanostructured Thin Films
edited by , Zheng Xie and Xiaofeng Zhao
submission deadline 27 Feb 2027 | 3 articles | Viewed by 3848 | Submission Open
Keywords: photoelectrochemical water splitting; CO2 reduction; photocatalysis; surface engineering; co-catalyst integration; sustainable energy conversion; thin-film heterojunctions; advanced functional nanomaterials
(This special issue belongs to the Section Photochemistry)
Advances in Natural Products and Their Biological Activities—2nd Edition
edited by , , Roseli Barbosa and Francisco Assis Bezerra Da Cunha
submission deadline 28 Feb 2027 | 13 articles | Viewed by 17039 | Submission Open
Keywords: phytochemical; natural product; phytotherapy; medicinal plants; biological activity; pharmaceutical formulations; biological activity; pharmacological or toxicology effects
(This special issue belongs to the Section Natural Products Chemistry)
Antimicrobial Compounds and Biocontrol Strategies in Food Microbiology and Safety submission deadline 28 Feb 2027 | 4 articles | Viewed by 10020 | Submission Open
Keywords: antimicrobial compound; natural; synthetic; microbial; application; biocontrol; food; crop; agricultural; pathogenic; spoilage; bacteria; mold; in vitro; in vivo; mechanisms of action; membrane disruption; enzyme inhibition; interference with microbial communication; resistance management
(This special issue belongs to the Section Food Chemistry)
Biotechnology and Biomass Valorization
edited by , and Parushi Nargotra
submission deadline 28 Feb 2027 | 7 articles | Viewed by 8128 | Submission Open
Keywords: biomass; conversion; utilization; enzyme; biological; microorganism; fermentation; high value-added product; biofuel; biogas; bioplastic; biochemical material; functional ingredient; bio-based material; metabolic engineering; synthetic biology; biorefining; bioresource; food waste; agricultural by-product; marine biological resource; extraction; purification; life cycle assessment (LCA)
(This special issue belongs to the Section Green Chemistry)
Molecular Insights into Functional Lipids in Food Chemistry
edited by and Siyu Zhang
submission deadline 28 Feb 2027 | 6 articles | Viewed by 8099 | Submission Open
Keywords: structured lipid; synthesis; crystallization; fatty acid; glyceride
(This special issue belongs to the Section Food Chemistry)
Recent Advances in Cannabis and Hemp Research—2nd Edition
edited by
submission deadline 28 Feb 2027 | 9 articles | Viewed by 8096 | Submission Open
Keywords: Cannabis sativa; hemp; cannabinoids; terpenes; phenolics; secondary metabolites; by-products; biological activity; protein; polysaccharide
(This special issue belongs to the Section Natural Products Chemistry)
Advances in Heterocyclic Synthesis, 2nd Edition
edited by
submission deadline 28 Feb 2027 | 6 articles | Viewed by 7555 | Submission Open
Keywords: heterocycles; stereoselective synthesis; sustainable synthesis; one-pot reactions; multicomponent reactions; catalysis
(This special issue belongs to the Section Organic Chemistry)
Opportunities and Challenges in Organic Optoelectronic Materials submission deadline 28 Feb 2027 | 3 articles | Viewed by 5801 | Submission Open
Keywords: organic semiconductors; organic photonics; inorganic/organic hybrid materials; excitons; electroluminescence; photovoltaics; vacuum/solution process; energy transfer
(This special issue belongs to the Section Materials Chemistry)
Bioactive Compounds as Modulators of Antioxidant Activity and Inflammatory Processes in Related Diseases
edited by
submission deadline 28 Feb 2027 | 6 articles | Viewed by 5400 | Submission Open
Keywords: natural bioactive compounds; antioxidant activities; anti-inflammatory activities; efficacy, safety, concentration-dependent effects; antioxidant/pro-oxidant balance
(This special issue belongs to the Section Natural Products Chemistry)
Heavy Metal Pollutants in Water, Wastewater and Sediments: From Occurrence and Determination to Removal and Recovery submission deadline 28 Feb 2027 | 5 articles | Viewed by 4711 | Submission Open
Keywords: heavy metals; analytical methods; wastewater; sludge; recycling; green chemistry; circular economy; sustainable development
(This special issue belongs to the Section Green Chemistry)
Bioactivity of Natural Compounds: From Plants to Humans, 2nd Edition
edited by
submission deadline 28 Feb 2027 | 4 articles | Viewed by 4595 | Submission Open
Keywords: natural compounds; blood vessel; endothelium dysfunction; advanced glycation end products (AGEs); reactive oxygen species (ROS); cytokines; ADMET properties; pharmacokinetics; gender difference
(This special issue belongs to the Section Natural Products Chemistry)
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