Research on 1,8-Naphthalimide Scaffold: Present and Future
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".
Deadline for manuscript submissions: 31 January 2027 | Viewed by 14
Special Issue Editor
Interests: sensing switches; fluorescent molecules; biosensors; molecular recognition
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Over the past few years, the 1,8-naphthalimide scaffold has attracted substantial attention owing to its distinctive structural features and broad functional versatility. Its conjugated architecture, comprising imide carbonyl groups integrated with a delocalized aromatic system, facilitates efficient intramolecular charge transfer, high electron affinity, and strong absorption in the visible region. Derivatives of 1,8-naphthalimide are readily accessible from 1,8-naphthalic anhydride and can be systematically tailored through substitution at both the imide nitrogen and the naphthalene core, enabling precise modulation of their electronic and photophysical properties, including red-shifted emission and pronounced environmental responsiveness. The advantageous characteristics of these derivatives—such as intense fluorescence, excellent photostability, and large Stokes shifts—have underpinned their widespread application in dyes, optoelectronic devices, and fluorescence-based sensing platforms for diverse analytes. Incorporation into polymeric systems further broadens their utility in advanced functional materials. In addition, these compounds exhibit significant biological activities, including anticancer, antimicrobial, and antiviral effects, while also serving as effective imaging agents. This Special Issue aims to highlight recent advances in 1,8-naphthalimide research in all fields, featuring original articles, communications, and comprehensive reviews.
Dr. Haishi Cao
Guest Editor
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Keywords
- 1,8-naphthalimide
- derivative of 1,8-naphthalimide
- synthesis of 1,8-naphthalimide
- spectroscopic properties of 1,8-naphthalimide
- fluorescent sensors
- biosensors
- sensing mechanisms
- photophysical properties
- crystal structures, computation, fluorescent dyes, cell imaging, textile dyes
- OLEDs
- electroluminescent materials
- liquid crystal displays
- ligand
- intercalators
- biomedical applications (analgesics)
- anti-depressants
- anti-tumor agents
- antiprotozoals
- antirheumatics
- antimicrobials
- antivirals
- anti-inflammatory agents
- enzyme inhibitors
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