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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Heterogeneous Catalysis for Green Chemistry
edited by Chen Li, and
submission deadline 31 Dec 2025 | Viewed by 70 | Submission Open
Keywords: green chemistry; heterogeneous catalysis; photocatalysis; electrocatalysis; thermal catalysis
(This special issue belongs to the Section Green Chemistry)
Molecular Spectroscopy and Molecular Structure
edited by , and Yukihiro Ozaki
submission deadline 31 Dec 2025 | Viewed by 69 | Submission Open
Keywords: molecular spectroscopy; molecular structure; applications in biological sciences; applications in materials science; molecular interaction; hydrogen bonds; methodological development; quantum chemical calculation
(This special issue belongs to the Section Photochemistry)
Natural Products as Antimicrobial and Antiviral Agents: From Extraction to Therapeutic Applications submission deadline 31 Dec 2025 | Viewed by 69 | Submission Open
Keywords: bioactive compounds; specialized metabolites; metabolomics; antiviral activity; antimicrobial activity; infectious diseases
(This special issue belongs to the Section Natural Products Chemistry)
Advances in Energetic Materials and Associated Detection Methods
edited by and Karolina Głosz
submission deadline 31 Dec 2025 | Viewed by 68 | Submission Open
Keywords: energetic materials; detection; sensors; fumes; risk assessment
(This special issue belongs to the Section Applied Chemistry)
Exploration of Organometallic Materials and Beyond for Sustainable Energy Applications
edited by and
submission deadline 31 Dec 2025 | Viewed by 64 | Submission Open
Keywords: metal complex; metallated polymer; organometallic materials; non-fullerene acceptor; triplet exciton; charge transfer; organic optoelectronic devices; organic photovoltaics; thick-film solar cell
(This special issue belongs to the Section Materials Chemistry)
Synthesis of Nanomaterials and Their Applications in Biomedicine—2nd Edition
edited by
submission deadline 31 Dec 2025 | Viewed by 63 | Submission Open
Keywords: nanomaterials; biomaterials; synthesis; characterization; diagnosis; treatment; cytotoxicity; biocompatibility
(This special issue belongs to the Section Materials Chemistry)
Fluorescent Molecular Tools for Brain-Wide Neuroscience Research
edited by Sheng Xie
submission deadline 31 Dec 2025 | Viewed by 62 | Submission Open
Keywords: histochemical method; fluorescent probes; brain-wide 3D imaging; neuropathology; immunofluorescence labeling; transgenic labeling; small-fluorophore labeling; metallophilic labeling; virus-based labeling
(This special issue belongs to the Section Cross-Field Chemistry)
Unveiling the Applications of Bioactive Compounds in Functional Foods for Optimal Human Health—2nd Edition
edited by and
submission deadline 31 Dec 2025 | Viewed by 61 | Submission Open
Keywords: functional foods; bioactive ingredients; health benefits; immune function; gut health; disease prevention
(This special issue belongs to the Section Food Chemistry)
Recent Advances on Biomass Conversion and CO2 Valorization: Steeping Towards a Circular Economy, 2nd Edition
edited by and Eva Castillejos-Lopéz
submission deadline 31 Dec 2025 | Viewed by 60 | Submission Open
Keywords: CO2 valorization; biomass conversion; catalysis
(This special issue belongs to the Section Green Chemistry)
Current Development Prospects of Novel Nanocatalysts
edited by Fengyu Gao
submission deadline 31 Dec 2025 | Viewed by 60 | Submission Open
Keywords: novel nanocatalysts; pollutant purification; environmental catalysis technology; precious metals; metal/alloys; metal oxides; non-metallic materials; environmental protection; gas purification; wastewater treatment; soil remediation; solid waste management; carbon neutrality
(This special issue belongs to the Section Green Chemistry)
Recent Research on Photocatalysis for Energy Storage and Conversion submission deadline 31 Dec 2025 | Viewed by 59 | Submission Open
Keywords: photocatalyst; photo/electrocatalyst; energy storage and conversion; photogenerated carrier; carbon neutrality; semiconductors
(This special issue belongs to the Section Photochemistry)
Synthesis, Properties, and Applications of Chiral Molecules
edited by José Luis Olivares-Romero
submission deadline 31 Dec 2025 | Viewed by 58 | Submission Open
Keywords: asymmetric catalysis; new chiral catalyst; stereoselective synthesis of natural products and analogs; chiral auxiliaries and reagents; computational and mechanistic studies of chiral processes; stereochemical characterization (e.g.; ECD; VCD; NMR; XRD); chirality in pharmaceutical development (ADMET; enantioselective binding); enantioselective recognition; sensors; and separation technologies; chiral materials in optoelectronics; polymers; and supramolecular chemistry; green and sustainable strategies for chiral synthesis
(This special issue belongs to the Section Organic Chemistry)
Chemistry Applied to Enhanced Oil Recovery
edited by and Mingwei Gao
submission deadline 31 Dec 2025 | Viewed by 56 | Submission Open
Keywords: advanced chemical materials for EOR; oil– gas field chemical working fluids; molecular engineering of EOR materials; reservoir chemical compatibility; chemical flooding enhancement mechanisms
(This special issue belongs to the Section Applied Chemistry)
Synthesis and Application of Chalcogen-Containing Organic Compounds submission deadline 31 Dec 2025 | Viewed by 53 | Submission Open
Keywords: organoselenium compounds; organotellurium compounds; organosulfur compounds; electrophilic chalcogenation; nucleophilic chalcogenation; organochalcogen compounds in material science; elemental chalcogen; C– X bond formation (X = S; Se; Te); pharmacological properties
(This special issue belongs to the Section Organic Chemistry)
Selectivity and Theoretical Studies of Cycloaddition Reactions submission deadline 31 Dec 2025 | Viewed by 51 | Submission Open
Keywords: cycloaddition; selectivity; density functional theory (DFT); reaction mechanisms; catalysis; stereocontrol
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Photocatalytic Nanocomposites: Design, Mechanisms and Applications
edited by Ramona-Crina Suciu
submission deadline 31 Dec 2025 | Viewed by 49 | Submission Open
Keywords: photocatalytic; nanocomposites; matrix; reinforcement; nanomaterials
(This special issue belongs to the Section Nanochemistry)
Nanomaterial-Based Sensors for Food Safety Analysis
edited by and
submission deadline 31 Dec 2025 | Viewed by 49 | Submission Open
Keywords: nanomaterial-based sensors; electrochemical/optical sensors; pathogen/toxin/pesticide/heavy metal ion detection; point-of-care testing; on-site; all-in-one; sensitivity enhancement
(This special issue belongs to the Section Nanochemistry)
Metal Oxide Nanomaterials: Synthesis, Structures and Optical Properties
edited by
submission deadline 31 Dec 2025 | Viewed by 48 | Submission Open
Keywords: metal oxide; nanomaterial; synthesis; structure; optical; electric; property; application; catalyst; photodegradation; solar cell; sensor; vector; drug delivery; nanomedicine; green technology; optical communication; metal doping; photocatalysis; band-gap engineering; defect characterization and engineering; biosensor; antibacterial
(This special issue belongs to the Section Nanochemistry)
Immunomodulatory and Anti-Inflammatory Activities of Natural Compounds with Adaptogenic Potential
edited by Daniel Załuski and Jakub Gębalski
submission deadline 31 Dec 2025 | Viewed by 44 | Submission Open
Keywords: adaptogens; immunomodulation; inflammation; phytochemicals; herbal medicine; cytokines; oxidative stress
(This special issue belongs to the Section Medicinal Chemistry)
Green Synthesis and Environmental Application of Biomass-Based Materials
edited by Congyu Zhang and
submission deadline 31 Dec 2025 | Viewed by 42 | Submission Open
Keywords: biomass; biochar; functional material; environmental application; green synthesis; sustainability
(This special issue belongs to the Section Green Chemistry)
Chromatographic Analysis of Pesticide Residues in Environmental Samples
edited by
submission deadline 31 Dec 2025 | Viewed by 41 | Submission Open
Keywords: chromatography coupled to mass spectrometry; targeted analysis; non-targeted analysis; validation; plants; soils
(This special issue belongs to the Section Analytical Chemistry)
Recyclable Supramolecular Polymer Materials
edited by
submission deadline 31 Dec 2025 | Viewed by 41 | Submission Open
Keywords: supramolecular polymers; recyclable materials; dynamic covalent chemistry; non-covalent interactions; self-healing materials; sustainable polymers; polymer recycling
(This special issue belongs to the Section Macromolecular Chemistry)
Applications of Natural Polymers in Biomedicine submission deadline 31 Dec 2025 | Viewed by 40 | Submission Open
Keywords: polymer biomaterials; biopolymers; proteins; polysaccharides; gels; hydrogels; scaffolds; films
(This special issue belongs to the Section Medicinal Chemistry)
Degradation of Soil Pollutants
edited by
submission deadline 31 Dec 2025 | Viewed by 36 | Submission Open
Keywords: degradation; remediation; analysis; pollutions; soil; new technology
(This special issue belongs to the Section Applied Chemistry)
Advances in Environmental Remediation and Wind–Sand Stabilization Materials
edited by
submission deadline 31 Dec 2025 | Viewed by 26 | Submission Open
Keywords: soil remediation and improvement; water purification; windbreak and sand fixation; air purification materials; natural eco-materials
(This special issue belongs to the Section Applied Chemistry)
Natural Products for Chronic Disease: Mechanisms and Applications
edited by and
submission deadline 31 Dec 2025 | Viewed by 21 | Submission Open
Keywords: natural products; chronic diseases; mechanism; herbal compound; drug delivery system; molecular modification
(This special issue belongs to the Section Natural Products Chemistry)
Advanced Delivery Systems for Therapeutic and Agro-Chemical Applications
edited by
submission deadline 31 Dec 2025 | Viewed by 21 | Submission Open
Keywords: micro- and nano-carriers; responsive; toxicology; safety; drug delivery
(This special issue belongs to the Section Applied Chemistry)
Bioactive Secondary Metabolites in Natural Products submission deadline 31 Dec 2025 | Viewed by 19 | Submission Open
Keywords: bioactive metabolites from mushrooms; medicinal plant metabolites; pro-health secondary metabolites from natural products; antiaging natural sources metabolites; natural dietary supplements
(This special issue belongs to the Section Natural Products Chemistry)
Emerging Technologies for Chemical Recovery of Spent Batteries
edited by Yuan Liang and
submission deadline 31 Dec 2025 | Viewed by 13 | Submission Open
Keywords: spent battery recycling; chemical recycling technologies; critical metal recovery; hydrometallurgy; bioleaching; circular economy
(This special issue belongs to the Section Green Chemistry)
Next-Generation Deep Eutectic Solvents for Sustainable Synthesis and Electrochemical Application
edited by
submission deadline 1 Jan 2026 | Viewed by 47 | Submission Open
Keywords: deep eutectic solvents; electrosynthesis; energy storage/conversion; chemical synthesis; wearable electronic devices; computation methods
(This special issue belongs to the Section Green Chemistry)
Advances in Amylases, 2nd Edition
edited by
submission deadline 15 Jan 2026 | Viewed by 272 | Submission Open
Keywords: enzyme; alpha-amylase enzyme; starch and glycogen; gut microbiome oriented study
(This special issue belongs to the Section Bioorganic Chemistry)
Review Papers in Materials Chemistry—2nd Edition submission deadline 15 Jan 2026 | Viewed by 73 | Submission Open
Keywords: materials chemistry; organic and inorganic materials; biomaterials; nanomaterials; hybrid materials; core-shell materials; thin films; self-assembling systems; tailored and unusual properties of materials
(This special issue belongs to the Section Materials Chemistry)
Transition Metal Complexes with Bioactive Ligands
edited by
submission deadline 16 Jan 2026 | 1 articles | Viewed by 472 | Submission Open
Keywords: transition metal complexes; DFT; QTAIM; biological activity; bioactive ligands; crystal structures
(This special issue belongs to the Section Organometallic Chemistry)
Isolation, Analysis, and Biological Activities of Secondary Metabolites Derived from Plants
edited by , Mindaugas Liaudanskas and
submission deadline 20 Jan 2026 | 4 articles | Viewed by 3101 | Submission Open
Keywords: isolation; analysis; phytochemical composition; biological activity
(This special issue belongs to the Section Natural Products Chemistry)
Advanced Polymer Composites for Sustainable Technologies: Synthesis, Characterization, and Performance
edited by Fujuan Liu
submission deadline 20 Jan 2026 | Viewed by 52 | Submission Open
Keywords: sustainable polymer composites; thermal insulation materials; fiber-reinforced composites; renewable energy applications; biodegradable composites; flexible electronics; light-emitting materials; Janus membrane design; nanomaterials; biomimetic design
(This special issue belongs to the Section Macromolecular Chemistry)
The Application of LC-MS in Pharmaceutical Analysis—2nd Edition
edited by Wing Lam and
submission deadline 30 Jan 2026 | 1 articles | Viewed by 499 | Submission Open
Keywords: LC– MS; chemical characterization; metabolite identification; metabolomics; pharmacokinetics
(This special issue belongs to the Section Analytical Chemistry)
State of the Art of Natural Antioxidants: Extraction, Detection and Biofunctions—2nd Edition submission deadline 30 Jan 2026 | Viewed by 148 | Submission Open
Keywords: antioxidant; phytochemistry; bioactive molecules; biotechnology; biomolecules; analytical chemistry; food chemistry; phytomedicine
(This special issue belongs to the Section Natural Products Chemistry)
Phosphorus-Based Compounds in Medicinal Chemistry
edited by
submission deadline 30 Jan 2026 | Viewed by 123 | Submission Open
Keywords: phosphorus-containing drugs; prodrugs; phosphonates; phosphinates; bioisosteres; enzyme inhibitors; drug design; drug discovery
(This special issue belongs to the Section Medicinal Chemistry)
Phytochemicals as Promising Molecules in Acute and Chronic Neurodegeneration
edited by
submission deadline 30 Jan 2026 | Viewed by 72 | Submission Open
Keywords: phytochemicals; nutrients; morphology; transmission electron microscopy; autophagy; proteasome; neurodegeneration; central nervous system; peripheral nervous system; sensory organs
(This special issue belongs to the Section Natural Products Chemistry)
Advances in Nanoscale Drug Delivery Technologies and Theranostics
edited by and Valérie Maraval
submission deadline 30 Jan 2026 | Viewed by 57 | Submission Open
Keywords: drug delivery; theranostics; nanoparticles; dendrimers; nanovesicle; nanomicelles; polymers; nanomaterials
(This special issue belongs to the Section Nanochemistry)
Molecular, Technological and Nutritional Aspects of Food Fortification and Processing submission deadline 30 Jan 2026 | Viewed by 57 | Submission Open
Keywords: food fortification and processing; molecular; technological; and nutritional aspects; food composition; functionality; nutritional quality
(This special issue belongs to the Section Food Chemistry)
Advanced Functional Quantum Dots: Design, Properties and Application submission deadline 30 Jan 2026 | Viewed by 34 | Submission Open
Keywords: quantum dots; functionalization; quantum modelling; novel materials; nanomaterials
(This special issue belongs to the Section Nanochemistry)
Design and Mechanisms of Photo(electro)catalysts for Water Splitting
edited by Zhaohui Zhou, Jiafeng Geng and
submission deadline 31 Jan 2026 | 3 articles | Viewed by 9377 | Submission Open
Keywords: photocatalysis; electrocatalysis; photoelectrocatalysis; photo(electro)catalysts synthesis; water splitting; hydrogen production; renewable fuels
(This special issue belongs to the Section Applied Chemistry)
Organosulfur and Organoselenium Chemistry II
edited by Ming Wang
submission deadline 31 Jan 2026 | 4 articles | Viewed by 9244 | Submission Open
Keywords: organosulfur; organoselenium; synthesis; transformation; application
(This special issue belongs to the Section Organic Chemistry)
Chemistry of Nucleosides and Nucleotides and Their Analogues submission deadline 31 Jan 2026 | 2 articles | Viewed by 7426 | Submission Open
Keywords: nucleosides; nucleotides; and nucleic acids; modified nucleosides and nucleotides; nucleoside and nucleotide analogues; antimetabolites; oligonucleotides; organic synthesis; bioorganic chemistry; medicinal chemistry
(This special issue belongs to the Section Organic Chemistry)
Boron Chemistry and Applications
edited by Liang Xu and Yu Wei
submission deadline 31 Jan 2026 | 5 articles | Viewed by 6918 | Submission Open
Keywords: boron-based materials; boron-based catalysts; boronyl synthons; boron neutron capture therapy
(This special issue belongs to the Section Organic Chemistry)
Applications of Fluorescent Sensors in Food and Environment submission deadline 31 Jan 2026 | 3 articles | Viewed by 6784 | Submission Open
Keywords: environmental pollutants; food quality; heavy metals and anions sensing; fluorescent quantum dots; luminescent metal organic frameworks (LMOFs); fluorescent polymers; fluorescent small molecules and supramolecular sensors; vapoluminescent materials
(This special issue belongs to the Section Materials Chemistry)
Analytical Insights into Bioactive Compounds in Pharmaceutical Formulations
edited by
submission deadline 31 Jan 2026 | 5 articles | Viewed by 6501 | Submission Open
Keywords: bioactive compounds; drug quality control; new pharmaceutical formulations; advanced analytical techniques; falsified medicines; methodologies
(This special issue belongs to the Section Analytical Chemistry)
Molecular Spectroscopy and Molecular Structure in Europe
edited by
submission deadline 31 Jan 2026 | 3 articles | Viewed by 4287 | Submission Open
Keywords: high-resolution molecular spectra; high-resolution experimental techniques; theory of molecular spectra; theory of molecular structure; effective Hamiltonians; quantum chemistry calculations; atmospheric applications; astrophysical applications
(This special issue belongs to the Section Cross-Field Chemistry)
Multifunctional Crystalline Porous Materials: Design, Synthesis and Applications
edited by Liangliang Zhang
submission deadline 31 Jan 2026 | 4 articles | Viewed by 3529 | Submission Open
Keywords: crystalline porous materials; design; synthesis and applications
(This special issue belongs to the Section Materials Chemistry)
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