Synthesis and Application of Chalcogen-Containing Organic Compounds
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 8
Special Issue Editors
Interests: organochalcogen compounds; natural compounds; green chemistry; organic synthesis; selenium compounds
Interests: cycloaddition reactions using metal catalysis or organocatalysis; coupling reactions catalyzed by transition metals (Pd, Cu, Ag, Ni); reactions with organochalcogens (S, Se and Te); reactions with organic boron reagents, synthesis and pharmacological evaluation of functionalized heterocycles
Interests: organic synthesis; green chemistry; organochalcogen compounds
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Chalcogen-containing organic compounds—molecules bearing sulfur, selenium, or tellurium atoms—have attracted increasing attention due to their broad chemical versatility, unique electronic properties, and wide-ranging applications in materials science, medicinal chemistry, and catalysis. Recent advances in synthetic methodologies have enabled the selective incorporation of chalcogens into complex frameworks through transition-metal catalysis, organocatalysis, and other redox strategies. These approaches provide access to a wide array of functionalized heterocycles, chalcogen-functionalized arenes, chalcogenium-containing heterocycles, dichalcogenocarbamates, β-hydroxy chalcogenides, chalcogenoxides, and chalcogenones.
In biological systems, sulfur- and selenium-containing compounds have shown potent antioxidant, anticancer, and antimicrobial activities, with several derivatives progressing into clinical investigation. In materials science, organochalcogen compounds serve as key components in organic electronics, including organic field-effect transistors (OFETs), organic photovoltaics (OPVs), and light-emitting diodes (OLEDs).
Despite progress, challenges remain in the development of efficient, greener, more sustainable synthetic routes and in understanding the structure–property relationships that govern their functions. Continued interdisciplinary efforts are essential to fully explore the potential of chalcogen-containing compounds in synthetic, biomedical, and materials frontiers.
For this Special Issue, we welcome original research articles and comprehensive reviews focused on recent advances in the synthesis, characterization, and application of chalcogen-containing organic compounds.
Dr. Angelita Manke Barcellos
Dr. Diego Alves
Prof. Dr. Eder João Lenardão
Guest Editors
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Keywords
- organoselenium compounds
- organotellurium compounds
- organosulfur compounds
- electrophilic chalcogenation
- nucleophilic chalcogenation
- organochalcogen compounds in material science
- elemental chalcogen
- C–X bond formation (X = S; Se; Te)
- pharmacological properties
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