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Special Issue "New Aspects of Pharmacology and Toxicology of Antibacterial Drugs"
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 31 March 2023 | Viewed by 8493
Special Issue Editor
E-Mail Website1 Website2
Interests: molecular mechanism; risk assessment; natural detoxicates; signaling pathways; animal-derived food safety
Special Issues, Collections and Topics in MDPI journals
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Special Issue in Metabolites: Toxic Effects and Metabolic Regulations of Hazardous Chemicals in Animal-Derived Food
Special Issue in Metabolites: Bacteriostatic Effect of Natural Products and Their Effect on Human Metabolism
Special Issue in Molecules: Antibacterial Adjuvants Screening from Plants and Molecular Mechanism Investigation
Special Issue Information
Antibacterial drugs have been widely used for infection therapy worldwide, and they play an important role in human and animal health. Many antibiotics, such as b-lactams, aminoglycosides, polymyxins, and quinolones, have been widely used in clinical practice, and the primary mechanisms of action have been well established. However, more recent studies have indicated that many antibacterial drugs exhibit secondary killing mechanisms, including the induction of ROS production and apoptotic-like or metabolic modulation of cell death. Additionally, prolonged antibiotic treatment may lead to detrimental side effects in patients, including ototoxicity, nephrotoxicity, neurotoxicity, and tendinopathy, yet the mechanisms underlying the effects of antibiotics in mammalian systems remain unclear. Investigations on the new aspects of pharmacology and toxicology of antibacterial drugs, including new targets, new pathways, or new death mode, are very important in the development of attenuation strategies, combination therapy, and development of derivatives of these current clinical available antibacterial drugs.
This Special Issue aims to collect all new research aspects of pharmacology and toxicology of antibacterial drugs, including new targets, new pathways, new death mode, new combination therapy based on reduced toxicity or enhanced antibacterial effect, metabolic modulation, and so on.
Dr. Chongshan Dai
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2300 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- new targets
- new combination therapy
- new pathways
- metabolic modulation
- antibacterial drugs