The Toxic Effects of Mycotoxins and Underlying Molecular Mechanisms
A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Novel Methods in Toxicology Research".
Deadline for manuscript submissions: closed (16 May 2023) | Viewed by 15665
Special Issue Editor
Interests: antioxidants; oxidative stress; molecular mechanism; autophagy; ferroptosis; neurotoxicity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The secondary metabolites produced by fungi known as mycotoxins are capable of causing mycotoxicosis (diseases and death) in humans and animals. To date, more than 400 mycotoxins have been identified and most of them have exhibited various toxic effects. Nowadays, mycotoxins exposure threatens both animal and human health and have gained widespread concern. According to their toxic effects, mycotoxins are classified as neurotoxins, immunotoxins, hepatotoxins, nephrotoxins, etc. In the past 60 years, the molecular mechanisms of some mycotoxins have gained some progress involving oxidative stress, mitochondrial dysfunction, inflammatory response, immunosuppression, autophagy regulation and apoptotic cell death. However, so far, their critical molecular mechanisms remain largely unknown, which makes it difficult to find effective treatment strategies in a timely manner after mycotoxins poisons are found in humans and animals. Therefore, underlying the precise toxic mechanisms of mycotoxins is essential in the search for effective treatment strategies.
In this Special Issue, we aim to collate innovative original research and review articles that reveal new pathogenic pathways, toxic mechanisms, potential therapeutic strategies, and protective agents, presenting targeting mycotoxins-induced toxic effects in vivo and in vitro.
Dr. Chongshan Dai
Guest Editor
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Keywords
- mycotoxins
- in vivo
- in vitro
- toxic mechanisms
- therapeutic strategies
- protective agents
- new pathogenic pathways
- toxic effects
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