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Special Issue "Toxic Effects and Metabolic Regulations of Hazardous Chemicals in Animal-Derived Food"
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Animal Metabolism".
Deadline for manuscript submissions: 15 August 2023 | Viewed by 2427
Special Issue Editors
E-Mail Website1 Website2
Interests: molecular mechanism; risk assessment; natural detoxicates; signaling pathways; animal-derived food safety
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Interests: toxic effects; cell death; molecular mechanism; veterinary residues; risk assessment
Special Issue Information
Animal-derived food is all edible animal products, including eggs and milk, meat, and their products. Biological, chemical, and physical agents are three categories of safety hazards to animal-derived food safety. Chemical contaminants, including veterinary drugs, heavy metals, nanomaterials, environmental pollutants, feed additives, and natural toxins (such as mycotoxins and bacterial toxins) can occur in animal-derived food, and could cause various harmful effects to animals or humans, including hepatotoxicity, nephrotoxicity, reproductive toxicity, neurotoxicity, or cardiovascular toxicity. The toxic effects caused by chemical hazard contaminants are often complex and content-dependent. To develop the effective prevention and control strategies, understanding the precise molecular mechanisms of these chemical contaminants-caused toxic effects is required. It has reported that many chemical contaminants in the low dose could damage cellular DNA, lipids, and proteins, finally resulting in various serious toxic effects. Recent studies showed that some chemical hazard contaminants could induce metabolism-dependent cell death by affecting multiple metabolic pathways in cell autophagy and ferroptosis, including glycolysis, pentose phosphate pathway, hexosamine biosynthetic pathway, and tricarboxylic acid (TCA) cycle, These evidences reveal that metabolism regulations may play a critical role in chemical contaminants-induced toxic effects or cell death. In this Special Issue, we aim to collate innovative original research and review articles that reveal the toxic effects of chemical hazard contaminants, molecular mechanisms, and metabolic regulations by using in vitro and in vivo models.
Dr. Chongshan Dai
Prof. Dr. Haiyang Jiang
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- toxic effects
- metabolic regulations
- hazardous chemicals
- animal-derived food safety
- risk assessment
- cell death
- animal model
- in vitro model