Role of Cell Metabolism in Infective Diseases
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Endocrinology and Clinical Metabolic Research".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 2
Special Issue Editor
Interests: antioxidants; oxidative stress; molecular mechanism; autophagy; ferroptosis; neurotoxicity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The immunometabolic framework provides a novel perspective for understanding immune regulation through cell-intrinsic metabolic fluxes and metabolites in the context of infections, tumors, and inflammatory disorders. Pathogens frequently exploit host energy metabolism, primarily by modulating glucose uptake, catabolism, and gluconeogenesis to maintain lipid metabolism via key pathways including glycolysis, the tricarboxylic acid (TCA) cycle, mitochondrial respiration, and the pentose phosphate pathway.
Notably, numerous biosynthetic pathways, such as those involved in cholesterol, ceramide, sphingolipid, and fatty acid metabolism, are altered, highlighting the critical role of metabolic reprogramming in the molecular pathogenesis of infectious diseases. Investigating these intracellular metabolic shifts offers valuable mechanistic insights into disease progression, thereby facilitating the discovery of innovative therapeutic strategies and drug development opportunities.
In light of these advancements, this Special Issue invites contributions from researchers in the field, encompassing, but not limited to, the following areas:
- Dynamic changes and functional implications of cellular metabolism in infectious diseases.
- Novel mechanisms underlying disease onset and progression, as revealed by metabolic studies.
- Emerging concepts and therapeutic approaches that are grounded in immunometabolic research.
- Metabolism, immunity, and new compounds.
- Metabolites, immunology, and drug therapy.
We encourage submissions that explore these themes to further elucidate the intricate interplay between metabolism and infection, ultimately paving the way for groundbreaking interventions.
Prof. Dr. Chongshan Dai
Guest Editor
Manuscript Submission Information
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Keywords
- metabolites
- immunology
- drug therapy
- new compounds
- cellular metabolism
- infectious diseases
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