Advances in Microbial Biotechnological Approaches for Carbohydrate Biosynthesis
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Microbial Biotechnology".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 95
Special Issue Editors
Interests: glycosylation; glycotherapeutics; bioactive oligosaccharides; glycosaminoglycans; drug delivery
Interests: metabolic engineering; synthetic biology; glycoengineering; glycoconjugate vaccine; enzyme engineering
Special Issue Information
Dear Colleagues,
Carbohydrates play pivotal roles in biological systems, serving as energy sources, structural components, and signaling molecules. Recent advances in microbial biotechnology have revolutionized the biosynthesis of complex carbohydrates, enabling the sustainable production of functional oligosaccharides, glycoconjugates, and polysaccharides with applications in therapeutics, vaccines, and biomaterials. This Special Issue explores cutting-edge strategies, including synthetic biology, enzyme engineering, and metabolic pathway optimization, to enhance carbohydrate production. We invite contributions investigating innovative microbial platforms (e.g., engineered E. coli, yeast, or cyanobacteria), novel enzymatic tools (e.g., glycosyltransferases, phosphorylases), and computational approaches (e.g., AI-driven glycan design) to address challenges in yield, scalability, and structural precision. Topics can span from fundamental mechanistic studies to translational applications in medicine (e.g., glyco-vaccines, glycoproteins, and glycosaminoglycans) and industry (e.g., biodegradable polymers).
Prof. Dr. Haining Tan
Guest Editor
Dr. Yuhui Wang
Dr. Lele Liu
Guest Editor Assistants
Manuscript Submission Information
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Keywords
- microbial carbohydrate biosynthesis
- glycoengineering
- synthetic biology
- enzyme engineering
- glycoconjugate vaccines
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