Advances in Microbial Biotechnological Approaches for Carbohydrate Biosynthesis
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Microbial Biotechnology".
Deadline for manuscript submissions: 31 January 2026
Special Issue Editors
Interests: glycosylation; glycotherapeutics; bioactive oligosaccharides; glycosaminoglycans; drug delivery
Interests: metabolic engineering; synthetic biology; glycoengineering; glycoconjugate vaccine; enzyme engineering
Special Issue Information
Dear Colleagues,
Carbohydrates play pivotal roles in biological systems, serving as energy sources, structural components, and signaling molecules. Recent advances in microbial biotechnology have revolutionized the biosynthesis of complex carbohydrates, enabling the sustainable production of functional oligosaccharides, glycoconjugates, and polysaccharides with applications in therapeutics, vaccines, and biomaterials. This Special Issue explores cutting-edge strategies, including synthetic biology, enzyme engineering, and metabolic pathway optimization, to enhance carbohydrate production. We invite contributions investigating innovative microbial platforms (e.g., engineered E. coli, yeast, or cyanobacteria), novel enzymatic tools (e.g., glycosyltransferases, phosphorylases), and computational approaches (e.g., AI-driven glycan design) to address challenges in yield, scalability, and structural precision. Topics can span from fundamental mechanistic studies to translational applications in medicine (e.g., glyco-vaccines, glycoproteins, and glycosaminoglycans) and industry (e.g., biodegradable polymers).
Prof. Dr. Haining Tan
Guest Editor
Dr. Yuhui Wang
Dr. Lele Liu
Guest Editor Assistants
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
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Keywords
- microbial carbohydrate biosynthesis
- glycoengineering
- synthetic biology
- enzyme engineering
- glycoconjugate vaccines
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