Biotechnological Applications of Marine Photosynthetic Microorganisms

A special issue of Marine Drugs (ISSN 1660-3397). This special issue belongs to the section "Marine Biotechnology Related to Drug Discovery or Production".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 1645

Special Issue Editor


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Guest Editor
Department of Pharmaceutical & Biological Engineering, School of Chemical Engineering, Sichuan University, Chengdu 610065, China
Interests: microalgae; photosynthesis; polysaccharide; metabolic regulation; bioprocess engineering; microalgae for food development
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Special Issue Information

Dear Colleagues,

Marine photosynthetic microorganisms encompass a diverse collection of taxonomic groups, including both photosynthetic eukaryotes (microalgae) and prokaryotes (cyanobacteria and other photosynthetic bacteria). They play an important role in the Earth’s geochemical cycles and form the base of the ocean’s food web. Plenty of valuable biomolecules (such as lipids, carbohydrates, proteins, pigments, vitamins, minerals, etc.) can be found in marine photosynthetic microorganisms, which allows them to be potentially applied in pharmaceutical and food industries, cosmetics, health care, aquaculture, agriculture, and so on. Thanks to the high photosynthetic efficiency with potent CO2 fixation ability, fast growth rate, and flexible cultivation mode compared to higher plants, the cultivation of marine photosynthetic microorganisms for the production of valuable metabolites will definitely contribute to the blue-carbon bioeconomy.

This Special Issue focuses on promoting the biotechnological applications of marine photosynthetic microorganisms. Research studies on biology, biotechnology, and bioengineering of marine photosynthetic microorganisms for various metabolite production purposes will be highly welcomed. The topics may include but are not limited to, the following: (1) biosynthesis, physiology, and regulatory mechanisms for metabolite accumulation; (2) metabolic engineering and synthetic biology approaches for achieving high productivity and quality; (3) novel cultivation strategies, technologies, and facilities with intelligent process monitoring; (4) modeling and optimization of cultivation processes; (5) efficient extraction and purification of valuable compounds; and (6) the development and characterization of bioactive compounds.

Dr. Changhong Yao
Guest Editor

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Keywords

  • marine microalgae
  • marine cyanobateria
  • biosynthesis
  • biotechnology
  • metabolic engineering
  • synthetic biology
  • microalgal cultivation
  • process modeling
  • extraction
  • high-value compounds

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Published Papers (1 paper)

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Research

14 pages, 2393 KiB  
Article
Salicylic Acid Improved the Growth of Dunaliella salina and Increased the Proportion of 9-cis-β-Carotene Isomers
by Shuaicheng Xiang, Xiaoting Qiu, Xiaojun Yan, Roger Ruan and Pengfei Cheng
Mar. Drugs 2025, 23(1), 18; https://doi.org/10.3390/md23010018 - 1 Jan 2025
Cited by 1 | Viewed by 1347
Abstract
Dunaliella salina is an important source of natural β-carotene (containing 9-cis and all trans isomers) for industrial production. The phytohormone salicylic acid (SA) has been proven to have impacts on the stress resistance of higher plants, but research on microalgae is currently unclear. [...] Read more.
Dunaliella salina is an important source of natural β-carotene (containing 9-cis and all trans isomers) for industrial production. The phytohormone salicylic acid (SA) has been proven to have impacts on the stress resistance of higher plants, but research on microalgae is currently unclear. In this study, the effects of SA on the growth, biochemical composition, antioxidant enzyme activity, key enzymes of β-carotene synthesis, and cis-and trans-isomers of β-carotene in D. salina under different salt concentrations were investigated. The results were shown that at concentrations of 1.5, 2, and 2.5 M NaCl, the antioxidant enzyme activity and key enzymes for β-carotene synthesis in algal cells were significantly increased, but the content and proportion of 9-cis isomer in β-carotene isomers decreased. The addition of SA significantly increased the growth and antioxidant enzyme (SOD, MDA) activity, as well as the synthesis of key enzyme phytoene synthase (PSY), phytoene desaturase (PDS), and lycopene β cyclase (LCYB) of D. salina under high-salinity conditions. It is worth noting that under the treatment of SA, the proportion of 9-cis isomer in the three salt concentrations (1.5, 2, 2.5 M NaCl) significantly increased by 32.09%, 20.30%, and 11.32%, respectively. Moreover, SA can not only improve the salt tolerance of D. salina, but also increase the proportion of 9-cis isomer, with higher physiological activity in β-carotene, thereby enhancing the application value of D. salina. Full article
(This article belongs to the Special Issue Biotechnological Applications of Marine Photosynthetic Microorganisms)
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