Mechanisms and Novel Biomarkers in Chronic Inflammatory Diseases

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: 31 December 2026

Special Issue Editors


E-Mail Website
Guest Editor
Department of Pathophysiology, University of Split School of Medicine, 21000 Split, Croatia
Interests: biomarkers, IBD; cardiovascular disorders; diabetes; inflammation
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Pathophysiology, University of Split School of Medicine, 21000 Split, Croatia
Interests: IBS; SIBO; CAKUT; histology; cardiovascular disorders

Special Issue Information

Dear Colleagues,

We are pleased to invite you to contribute to our Special Issue dedicated to chronic inflammatory diseases, one of the most complex and rapidly evolving areas of modern biomedical research. Chronic inflammation represents a critical link between immune dysregulation, metabolic imbalance, and vascular dysfunction, playing a central role in the development of tissue damage and systemic complications.

Despite significant advances in therapeutic strategies, the molecular and cellular mechanisms underlying chronic inflammatory conditions remain incompletely understood. This Special Issue aims to bring together original research articles and comprehensive reviews that explore the interplay between persistent inflammation, immune regulation, and tissue remodeling across different organs and disease contexts.

A particular focus of this issue is the identification and validation of novel biomarkers with diagnostic, prognostic, or therapeutic relevance. Contributions addressing cytokine profiles, genetic and epigenetic factors, circulating microRNAs, metabolites, and microbiome-derived molecules, as well as translational and clinical studies supporting precision medicine approaches, are especially welcome.

By integrating basic, translational, and clinical perspectives, this Special Issue seeks to provide new insights into disease mechanisms, foster interdisciplinary collaboration, and ultimately contribute to improved patient care.

We warmly invite you to submit your latest work and look forward to your valuable contribution to this collection.

Dr. Josko Bozic
Dr. Nikola Pavlović
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • chronic inflammation
  • biomarkers
  • immune regulation
  • molecular mechanisms
  • precision medicine

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Published Papers

This special issue is now open for submission.
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