Responses of Aquatic Organisms to Environmental Stress

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Animal Science".

Deadline for manuscript submissions: 28 February 2027 | Viewed by 976

Special Issue Editors

East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China
Interests: aquatic toxicology; genetic breeding; nutriology; aquatic ecology

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Guest Editor
Laboratory of Integrated Rice-Fish Farming Ecosystem, Ministry of Agriculture and Rural Affairs, Eco-Environmental Protection Research Institute, Shanghai Academy of Agricultural Sciences, Shanghai 201403, China
Interests: aquatic nursery; ecological breeding; environmental toxicology; aquatic biology

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Guest Editor
Freshwater Fisheries Research Institute of Jiangsu Province, 79 Chating East Street, Nanjing 210017, China
Interests: freshwater fisheries; aquatic biology; environmental toxicology
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Special Issue Information

Dear Colleagues,

Aquatic animals are confronted with increasingly complex environmental stressors and their physiological adaptation mechanisms directly affect individual health and ecosystem balance. Stress, as a multi-factor-driven biological response process, involves processes ranging from neuroendocrine regulation to metabolic reprogramming and is an important defense strategy for organisms to cope with internal and external environmental changes. In different aquatic species groups, the manifestations of stress responses exhibit high diversity, including rapid hormone release and energy mobilization, as well as long-term adaptation processes such as immune regulation and oxidative stress response. In-depth understanding of the physiological basis, metabolic pathways and impact of stress responses on biological adaptability holds significant scientific value. Although there have been relevant research advancements, due to the diversity of aquatic species and the complexity of stress types, there are still numerous unknowns in their intrinsic response mechanisms.

This special issue is dedicated to promoting interdisciplinary research in this field and invites original research and review submissions related to stress responses in aquatic animals. The topics we focus on include, but are not limited to: physiological and endocrine mechanisms of stress responses, the interaction between energy metabolism and immune function, stress-related behavioral manifestations and adaptation mechanisms at the cellular and molecular levels. We particularly encourage comparative and integrated analyses of different life history stages and different ecological groups (including marine and freshwater, vertebrates and invertebrates). By gathering these studies, we hope to systematically reveal the stress adaptation strategies of aquatic animals in changing environments, providing a scientific basis for their health management, resource protection and sustainable utilization.

Dr. Yiming Li
Dr. Weiwei Lv
Dr. Qichen Jiang
Guest Editors

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Keywords

  • stress
  • metabolism
  • aquaculture
  • aquatic animals
  • animal physiology
  • molecular expression
  • adaptive mechanism

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Published Papers (2 papers)

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Research

19 pages, 2220 KB  
Article
Effects of Berberine on Growth Performance, Serum Biochemical Parameters, Hepatic Antioxidant Capacity and Metabolism in Monopterus albus
by Xinran Tao, Weiwei Huang, Yifan Zhao, Muyan Li, Yuning Zhang, Hang Yang, Wenzong Zhou and Mingyou Li
Life 2026, 16(5), 829; https://doi.org/10.3390/life16050829 (registering DOI) - 17 May 2026
Viewed by 103
Abstract
Intensive aquaculture of rice field eel (Monopterus albus) is constrained by oxidative stress induced by high-density culture resulting in growth inhibition, while prophylactic antibiotics pose escalating risks of drug resistance and food safety hazards. This study addresses the critical need for [...] Read more.
Intensive aquaculture of rice field eel (Monopterus albus) is constrained by oxidative stress induced by high-density culture resulting in growth inhibition, while prophylactic antibiotics pose escalating risks of drug resistance and food safety hazards. This study addresses the critical need for developing efficient, environmentally friendly functional feed additives as sustainable growth promoters in intensive aquaculture. To investigate the dietary berberine (BBR) effect on promoting growth performance, hepatic antioxidant capacity and metabolism in M. albus, four experimental groups were established: control (CON, 0 mg/kg) and berberine-supplemented groups (BBR25, 25 mg/kg; BBR50, 50 mg/kg; BBR100, 100 mg/kg). Growth performance, serum biochemical parameters, hepatic antioxidant capacity, and liver metabolomics (LC-MS) were evaluated after the 8-week feeding trial. BBR50 and BBR100 had significantly increased final weight, weight gain rate (WG), and survival rate (SR), while reducing feed conversion ratio (FCR) (p < 0.05). Serum glucose (Glc), total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDL-C) were decreased (p < 0.05), while high-density lipoprotein cholesterol (HDL-C) and phosphofructokinase (PFK) activity were increased (p < 0.05). Alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP) were significantly reduced (p < 0.05). Superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) were upregulated (p < 0.05), whereas malondialdehyde (MDA) was downregulated (p < 0.05). Metabolomics identified 98 differential metabolites, with significant enrichment of metabolites associated with arachidonic acid metabolism, histidine metabolism, arginine/proline metabolism, tryptophan metabolism, and pathways related to mTOR signaling. Overall, dietary supplementation with 50 mg/kg BBR emerged as a practically favorable dose among the tested concentrations for promoting growth performance and feed utilization efficiency, whereas 100 mg/kg BBR was associated with lipid and amino acid metabolic alterations suggestive of metabolic reprogramming and antioxidant-related shifts, without conferring additional growth benefits. Full article
(This article belongs to the Special Issue Responses of Aquatic Organisms to Environmental Stress)
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20 pages, 4683 KB  
Article
Integrating Transcriptomics and Gut Microbiota Analysis Reveals Adaptive Mechanisms of Alkaline Stress on the Molting and Intestinal Immune Responses in Pacific White Shrimp, Litopenaeus vannamei
by Yiming Li, Yucong Ye, Junling Ma, Zongli Yao, Yan Li, Pengcheng Gao, Yuxin Wang, Zihe Cheng, Yunlong Zhao and Qifang Lai
Life 2026, 16(4), 652; https://doi.org/10.3390/life16040652 - 12 Apr 2026
Viewed by 605
Abstract
In northwestern China, there is an abundance of saline-alkali water resources, but their high alkalinity severely restricts the development of inland saline-alkali water aquaculture. As an important aquaculture species, the whiteleg shrimp, Litopenaeus vannamei, shows an unclear physiological adaptation mechanism under high-alkaline [...] Read more.
In northwestern China, there is an abundance of saline-alkali water resources, but their high alkalinity severely restricts the development of inland saline-alkali water aquaculture. As an important aquaculture species, the whiteleg shrimp, Litopenaeus vannamei, shows an unclear physiological adaptation mechanism under high-alkaline stress. In this study, multi-omics and physiological methods were used to systematically reveal the effects of high-alkaline stress on the molt, antioxidation response, and immune defense in L. vannamei. The results showed that high-alkaline stress caused damage to the intestinal tissues of the shrimp and weakened the mucous barrier function, which was accompanied by a significant decrease in the activities of antioxidant enzymes (SOD, CAT, and GPx) and non-specific immune indicators (PO and LZM) (p < 0.05). The transcriptome results showed that the expression of genes related to chitin metabolism and calcium ion binding was upregulated, whereas that of genes related to muscle contraction and cell skeleton construction was downregulated. The structure of the intestinal microbiota changed significantly, with a decrease in microbiota diversity, whereas the abundance of potential pathogenic species (e.g., Photobacterium) increased. These results provide a theoretical basis for clarifying the molting response and antioxidant defense mechanism of L. vannamei in high-alkaline environments, with significance for saline-alkali water aquaculture practices. Full article
(This article belongs to the Special Issue Responses of Aquatic Organisms to Environmental Stress)
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