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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancements in Individualized Plastic and Reconstructive Surgery: Second Edition
edited by , Peter Niclas Broer and Denis C. Ehrl
submission deadline 24 Jan 2027 | 4 articles | Viewed by 4829 | Submission Open
Keywords: patient-specific reconstructive procedures; microsurgical precision techniques; autologous tissue transplantation; digital imaging and customization; biomaterials in reconstructive surgery; tissue engineering for plastic reconstruction; flap surgery innovations; personalized cleft surgery; personalized aesthetic surgery
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Updates in the Diagnosis, Imaging, and Treatment of Retinal and Macular Diseases
edited by
submission deadline 24 Jan 2027 | 4 articles | Viewed by 4254 | Submission Open
Keywords: retinal diseases; macular degeneration; diagnostic imaging; OCT/OCTA; artificial intelligence; deep learning; clinical ophthalmology; gene therapy; treatment innovations
(This special issue belongs to the Section Ophthalmology)
Current Insights into Atopic Dermatitis
edited by Francisco José Navarro-Trivino
submission deadline 24 Jan 2027 | Viewed by 151 | Submission Open
Keywords: atopic dermatitis; type 2 inflammation; skin barrier; biologics; JAK inhibitors; precision medicine; chronic pruritus
(This special issue belongs to the Section Dermatology)
Artificial Intelligence (AI) and Deep Learning (DL) in Medical Imaging submission deadline 25 Jan 2027 | 6 articles | Viewed by 15812 | Submission Open
Keywords: artificial intelligence; deep learning; imaging; diagnosis; precision medicine; oncologic
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Advances in Diagnosis and Management of Pancreatobiliary Disorders—2nd Edition
edited by
submission deadline 25 Jan 2027 | 11 articles | Viewed by 13099 | Submission Open
Keywords: pancreas diseases; pancreatic tumors; biliary tract diseases and neoplams; ERCP; EUS; cholangioscopy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Cardiogenic Shock and Cardiac Arrest: Updates, Challenges and Opportunities
edited by
submission deadline 25 Jan 2027 | 5 articles | Viewed by 9227 | Submission Open
Keywords: cardiac arrest; extracorporeal membrane oxygenation; extracorporeal CPR; cardiopulmonary resuscitation; cardiogenic shock; resuscitation; prognostication
(This special issue belongs to the Section Cardiology)
Advances in Gastroenterology and Hepatology: Bridging Basic Science, Clinical Insights, and Translational Medicine submission deadline 25 Jan 2027 | 6 articles | Viewed by 8496 | Submission Open
Keywords: hepatology; gastroenterology; IBD; IBS; MASLD; liver cirrhosis; artificial intelligence; disorders of gut–brain interaction; cancer; gut microbiota; diagnosis; management
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Non-Small Cell Lung Cancer (NSCLC): Recent Advances in Clinical Diagnosis and Treatment
edited by
submission deadline 25 Jan 2027 | 10 articles | Viewed by 8166 | Submission Open
Keywords: novel screening tool; cancer biomarkers; predictive marker of immunotherapy; targeted therapy; radiotherapy; non-small cell lung cancer
(This special issue belongs to the Section Oncology)
Clinical Advances in Spinal Neurosurgery
edited by Jang-Won Yoon
submission deadline 25 Jan 2027 | 6 articles | Viewed by 7464 | Submission Open
Keywords: minimally invasive spine surgery; lateral lumbar interbody fusion; endoscopic spine surgery; patient-reported out-comes; functional assessment; perioperative care; surgical decision-making
(This special issue belongs to the Section Clinical Neurology)
Autoimmune-Induced Alopecia and Emerging Therapies in Hair Loss—2nd Edition
edited by David Saceda-Corralo
submission deadline 25 Jan 2027 | 2 articles | Viewed by 7408 | Submission Open
Keywords: autoimmune-induced alopecia; alopecia areata; cicatricial alopecia; occurs; hair loss; frontal fibrosing alopecia
(This special issue belongs to the Section Dermatology)
Current Advances in General and Regional Anesthesia
edited by Eleni Laou, Eleana Garini and
submission deadline 25 Jan 2027 | 3 articles | Viewed by 6562 | Submission Open
Keywords: anesthesiology; general anesthesia; regional anesthesia; pediatric anesthesia; perioperative medicine; surgery; postoperative outcome; monitoring; analgesia; safety
(This special issue belongs to the Section Anesthesiology)
Current Advances and Future Perspectives in Interventional Cardiology
edited by
submission deadline 25 Jan 2027 | 4 articles | Viewed by 5335 | Submission Open
Keywords: trans-catheter valve repair and replacement; advanced coronary intervention; AI in decision making for trans-catheter aortic root and arch replacement; LAA occlusion; anti-arrhythmic therapy; right side of the heart
(This special issue belongs to the Section Cardiology)
Broadening the Knowledge of Autism Spectrum Disorder in Adulthood: Advances in Diagnosis, Assessment and Treatment
edited by
submission deadline 25 Jan 2027 | 1 articles | Viewed by 5052 | Submission Open
Keywords: autism spectrum disorder; adulthood; autism; comorbidity; gender; age-adjusted
(This special issue belongs to the Section Mental Health)
Current Perspectives on the Clinical Management of Respiratory Diseases submission deadline 25 Jan 2027 | 3 articles | Viewed by 4408 | Submission Open
Keywords: COPD; acute exacerbations; biomarkers; clinical trials; bronchiectasis; respiratory infections
(This special issue belongs to the Section Respiratory Medicine)
Clinical Updates in Reproductive Endocrinology: 2nd Edition
edited by Iwona Bojar and
submission deadline 25 Jan 2027 | 3 articles | Viewed by 4192 | Submission Open
Keywords: reproductive endocrinology; endocrine diseases in pregnancy; infertility; endocrine diagnostics in infertility; long-term consequences of endocrine disorders; therapy for endocrine disorders
(This special issue belongs to the Section Obstetrics & Gynecology)
Multiple Sclerosis and Demyelinating Disease: Clinical Treatment and Management
edited by Sotirios Giannopoulos
submission deadline 25 Jan 2027 | 3 articles | Viewed by 4135 | Submission Open
Keywords: multiple sclerosis; demyelinating disease; comorbidities; disease modifying treatments; neuromuscular disorder; myasthenia gravis
(This special issue belongs to the Section Clinical Neurology)
Advances in Clinical Management of Temporomandibular Joint Diseases submission deadline 25 Jan 2027 | 3 articles | Viewed by 3409 | Submission Open
Keywords: minimally invasive surgical procedure; artificial intelligence; temporomandibular joint disorders; temporomandibular disorders; temporomandibular joint
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Challenges and Opportunities in Application of Laparoscopic, Robotic and Other Technological Advances in Gastrointestinal Surgery
edited by and Fabrizio Panaro
submission deadline 25 Jan 2027 | 3 articles | Viewed by 3304 | Submission Open
Keywords: robotic surgery; laparoscopic surgery; artificial intelligence; technological advances
(This special issue belongs to the Section General Surgery)
Recent Clinical Advances in Reconstructive Urology and Prosthetic Surgery
edited by Elisa Berdondini and
submission deadline 25 Jan 2027 | 1 articles | Viewed by 2877 | Submission Open
Keywords: reconstructive urology; penile prosthesis; artificial urinary sphincter; urethral stricture; reconstructive surgery; minimally invasive procedures
(This special issue belongs to the Section Nephrology & Urology)
High-Risk Pregnancy Management: From Prenatal Care to Postpartum Outcomes
edited by
submission deadline 25 Jan 2027 | 2 articles | Viewed by 2093 | Submission Open
Keywords: high-risk pregnancy; prenatal care; postpartum outcomes; postpartum mental health; birth trauma; AI in obstetrics; medico-legal liability; equity & culturally safe care; indigenous and rural/remote care; EMR-enabled decision support; quality trend monitoring; maternal morbidity and mortality; perinatal morbidity; standardized care bundles & pathways
(This special issue belongs to the Section Obstetrics & Gynecology)
Advancing Trends and Strategies in Vascular and Endovascular Surgery
edited by Karin Pfister and Fiona Rohlffs
submission deadline 25 Jan 2027 | 2 articles | Viewed by 1289 | Submission Open
Keywords: vascular surgery; endovascular surgery; carotid endarterectomy; peripheral vascular diseases; vascular imaging; aortic diseases; aortic aneurysm; arteriovenous malformation; pelvic venous disorder; endovenous procedures; pal-liative therapy concept
(This special issue belongs to the Section Vascular Medicine)
Interaction Between Systemic Diseases and Oral Diseases: 2nd Edition
edited by
submission deadline 25 Jan 2027 | 2 articles | Viewed by 1207 | Submission Open
Keywords: medical dental interaction; saliva; xerostomia; diagnostics; inflammatory bowel disease; cancer survivors; dental erosion; Sjögren’s disease; liver transplantation
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Management and Update of Aortic Dissection and Aortic Aneurysm Diseases
edited by
submission deadline 25 Jan 2027 | 1 articles | Viewed by 1127 | Submission Open
Keywords: aortic aneurysm; aortic dissection; aortic surgery; endovascular procedures
(This special issue belongs to the Section Cardiovascular Medicine)
Further Advances in Electrocardiography, Cardiac Arrhythmias, and Arrhythmogenic Disorders: 2nd Edition
edited by
submission deadline 25 Jan 2027 | 1 articles | Viewed by 1120 | Submission Open
Keywords: electrocardiography; cardiac arrhythmias; genetics; cardiac pacing; implantable cardioverter defibrillators; cardiac resynchronization therapy; magnetic resonance imaging; catheter ablation; arrhythmogenic disorders; channelopathy; cardiomyopathy
(This special issue belongs to the Section Cardiology)
Musculoskeletal Imaging and Intervention: 2nd Edition submission deadline 25 Jan 2027 | 2 articles | Viewed by 1004 | Submission Open
Keywords: ultrasound; invasive physiotherapy; minimally invasive surgical procedures; magnetic resonance; image analysis
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Advanced Image-Enhanced Endoscopy and Colonoscopy
edited by , and Simona Di Caro
submission deadline 25 Jan 2027 | 1 articles | Viewed by 1002 | Submission Open
Keywords: gastrointestinal endoscopy; colorectal cancer; endoscopic screening; artificial intelligence; chromoendoscopy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Cutting-Edge Strategies in Periodontal Disease: Proactive Prevention, Early Diagnosis, and Optimal Management
edited by
submission deadline 25 Jan 2027 | Viewed by 177 | Submission Open
Keywords: periodontitis; herbal medicine; dental plaque; pathogenesis related proteins; root planing; instrumentation; ultrasonic therapy
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Implant-Supported Prosthetic Rehabilitation: Current Concepts, Emerging Technologies and Long-Term Outcomes
edited by , Marius Manole and Cosmin Sinescu
submission deadline 25 Jan 2027 | Viewed by 108 | Submission Open
Keywords: prosthetic rehabilitation; dental implants; dental restorations; zirconia; digital dentistry; long-term outcomes; clini-cal biomaterials; immediate loading; clinical biomedical engineering; full-arch restoration; peri-implant health
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Technological Advances in Lumbar and Thoracic Spine Surgery: Current Evidence and Future Perspectives
edited by
submission deadline 25 Jan 2027 | Viewed by 91 | Submission Open
Keywords: lumbar spine surgery; thoracic spine surgery; minimally invasive spine surgery; endoscopic spinal surgery; robotic-assisted surgery; artificial intelligence; machining learning; lumbar interbody fusion; spinal biologics; adjacent segment disease; patient-reported outcomes; revision spinal surgery; ossification of posterior longitudinal ligament
(This special issue belongs to the Section Orthopedics)
Mind–Body Connection: The Impact of Mental Health on Physical Well-Being
edited by
submission deadline 30 Jan 2027 | 5 articles | Viewed by 11705 | Submission Open
Keywords: mind–body connection; mental health; well-being; metabolic balance; immune system; chronic medical conditions; body perception; self-image; eating disorders; psychosomatic disorders; psychosomatic medicine; innovative thera-peutic approaches; mindfulness; mind-wandering; integrated healthcare
(This special issue belongs to the Section Mental Health)
Applications of Artificial Intelligence (AI) in Surgery submission deadline 30 Jan 2027 | Viewed by 451 | Submission Open
Keywords: artificial intelligence; machine learning; surgical robotics; computer vision; predictive analytics; surgical decision support; perioperative care; surgical outcomes; digital surgery
(This special issue belongs to the Section General Surgery)
The Athlete’s Heart in the Era of Precision Medicine: From Clinical Characterization to Personalized Risk
edited by and Lucrezia Netti
submission deadline 30 Jan 2027 | Viewed by 122 | Submission Open
Keywords: athlete’s heart; exercise prescription; cardiac remodeling; sports cardiology; risk stratification; arrhythmias
(This special issue belongs to the Section Cardiovascular Medicine)
The Current Status and Future Directions of Pancreatoduodenectomy and Pancreatectomy
edited by , and Somaiah Aroori
submission deadline 31 Jan 2027 | 5 articles | Viewed by 8968 | Submission Open
Keywords: pancreatic resection types; techniques and modifications; anastomotic techniques; open resection; minimally invasive surgery; laparoscopic resection; robotic resection; hybrid resection techniques; pancreatic resection post neoadjuvant treatment; lymphadenectomy; vascular resections; organ-sparing procedures; radicality; indications; complications
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Personalized Management of Abdominal Surgery and Complications
edited by Ioannis Mantzoros and
submission deadline 31 Jan 2027 | 3 articles | Viewed by 2874 | Submission Open
Keywords: personalized medicine; abdominal surgery; complications; emergency; innovative surgery
(This special issue belongs to the Section General Surgery)
Recent Advances and Future Perspectives of Subarachnoid Hemorrhage
edited by Alexandros Doukas and Athanasios K. Petridis
submission deadline 31 Jan 2027 | 2 articles | Viewed by 2487 | Submission Open
Keywords: subarachnoid hemorrhage; neuromonitoring; neurocritical care; neurointerventions; neurointensive care
(This special issue belongs to the Section Clinical Neurology)
Orthopedic Trauma Surgery: Techniques, Challenges and Rehabilitation
edited by Julian Scherer
submission deadline 31 Jan 2027 | Viewed by 856 | Submission Open
Keywords: orthopedic trauma surgery; minimally invasive osteosynthesis; spinal trauma; polytrauma management; digital follow-up and rehabilitation
(This special issue belongs to the Section Orthopedics)
Innovations in Electrical Therapy for Heart Failure
edited by Zoltán Csanádi and
submission deadline 31 Jan 2027 | Viewed by 249 | Submission Open
Keywords: cardiac arrhythmias; atrial fibrillation; cardiac pacing; implantable cardioverter-defibrillators; cardiac resynchronization therapy; conduction system pacing; catheter ablation; arrhythmogenic disorders; heart failure; autonomic nervous system modulation
(This special issue belongs to the Section Cardiology)
New Insights on Pharmacologic and Non-Pharmacologic Therapy of Advanced Heart Failure
edited by
submission deadline 5 Feb 2027 | 1 articles | Viewed by 1043 | Submission Open
Keywords: advanced heart failure (AHF); mechanical circulatory support systems; heart transplantation (HTx); immunosuppression; cardiac allograft rejections
(This special issue belongs to the Section Cardiology)
Clinical Outcomes Improvement and Perioperative Management of Surgical Patients: 3rd Edition submission deadline 10 Feb 2027 | 6 articles | Viewed by 5695 | Submission Open
Keywords: clinical outcomes; surgery; quality; quality of life; quality improvement; postoperative; morbidity; postoperative care
(This special issue belongs to the Section General Surgery)
Clinical Advances in Pediatric Critical Care Medicine
edited by
submission deadline 10 Feb 2027 | 6 articles | Viewed by 5431 | Submission Open
Keywords: acute renal failure; acute respiratory failure; pediatric oncology; pediatric ICU; pediatric critical care medicine; multi-organ dysfunction
(This special issue belongs to the Section Clinical Pediatrics)
Surgical Management of Maxillofacial Fractures and Reconstruction of Facial Deformities
edited by , and Francesco Arcuri
submission deadline 10 Feb 2027 | 5 articles | Viewed by 4654 | Submission Open
Keywords: head and neck reconstruction; facial fractures; minimally invasive treatments; facial reconstruction; bioengineering in head and neck disorders; CAD/CAM in maxillo facial trauma and deformities
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Advancements and Future Directions in Clinical Psychosis submission deadline 10 Feb 2027 | 3 articles | Viewed by 4526 | Submission Open
Keywords: clinical psychosis; schizophrenia spectrum disorders; early detection of psychosis; treatment-resistant psychosis; long-term outcomes; personalized psychiatry; digital mental health; AI in psychiatry; neurocognitive interventions; psychosocial therapies; translational psychiatry; interdisciplinary mental health; psychosis clinical trials; innova-tive diagnostic tools
(This special issue belongs to the Section Mental Health)
Cardiac Arrest and Postcardiac Arrest Care: State of the Art and Future Directions
edited by and Soheil Saadat
submission deadline 10 Feb 2027 | 4 articles | Viewed by 3416 | Submission Open
Keywords: out-of-hospital cardiac arrest; cardiopulmonary resuscitation; postcardiac arrest syndrome; postcardiac arrest care; survival; neurologic outcomes
(This special issue belongs to the Section Emergency Medicine)
Pediatric Hearing Loss: Advances in Early Detection, Intervention and Family-Centered Care submission deadline 10 Feb 2027 | 2 articles | Viewed by 3390 | Submission Open
Keywords: pediatric hearing loss; early intervention; early identification of language and communication disorders; develop-mental language disorders; predictors of outcomes; newborn hearing screening; pediatric audiology
(This special issue belongs to the Section Otolaryngology)
Clinical and Diagnostic Strategies for Glioma Treatment
edited by and Egils Valeinis
submission deadline 10 Feb 2027 | 5 articles | Viewed by 2688 | Submission Open
Keywords: glioma; glioblastoma; astrocytoma; oligodendroglioma; IDH; neuro-oncology; neurosurgery; radiotherapy; neuropathology; diagnostics; treatment
(This special issue belongs to the Section Clinical Neurology)
Advances in Maternal–Fetal Medicine
edited by
submission deadline 10 Feb 2027 | 1 articles | Viewed by 1704 | Submission Open
Keywords: maternal–fetal medicine; obstetric ultrasound; preterm birth; preeclampsia; pregnancy complications; artificial intelligence
(This special issue belongs to the Section Obstetrics & Gynecology)
Diagnosis and Treatment of Pediatric Endocrine Disorders—Focus on Rare Conditions
edited by Sophia Sakka
submission deadline 10 Feb 2027 | Viewed by 1595 | Submission Open
Keywords: pediatric endocrinology; diabetes mellitus in children; bone metabolism disorders; clinical diagnosis; therapeutic strategies; skeletal dysplasias; rare endocrine conditions; pediatric type 1 diabetes; rickets management; genetic conditions; pediatric hormone therapy; achondroplasia
(This special issue belongs to the Section Endocrinology & Metabolism)
New Advances in Cardiovascular Diseases: The Cutting Edge—2nd Edition
edited by
submission deadline 10 Feb 2027 | 1 articles | Viewed by 416 | Submission Open
Keywords: cardiovascular disease (CVD); preventive cardiology; cardiac pharmacology; coronary artery disease (CAD); heart failure (HF); atrial fibrillation (AF); supraventricular and ventricular arrhythmias
(This special issue belongs to the Section Cardiovascular Medicine)
Cardiomyopathy: Diagnosis and Therapeutic Advances
edited by Ilaria Dentamaro and Annagrazia Cecere
submission deadline 10 Feb 2027 | Viewed by 402 | Submission Open
Keywords: cardiomiopathy; cardiac magnetic resonance (CMR); advanced echocardiography; heart failure; hypertrophic cardiomyopathy
(This special issue belongs to the Section Cardiology)
Pediatric Spinal Dysraphisms, Tethered Cord Syndrome and Scoliosis: Controversies, Recent Advances, and Future Challenges
edited by Taemin Oh
submission deadline 10 Feb 2027 | Viewed by 118 | Submission Open
Keywords: pediatric spine; scoliosis; cervical instability; spinal dysraphism; tethered cord syndrome; myelomeningocele; neural tube defects; spinal cord malformations; spinal column shortening
(This special issue belongs to the Section Clinical Neurology)
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