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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Endovascular Stroke Treatment: Latest Advances and Challenges
edited by Daniele Giuseppe Romano and Giulia Frauenfelder
submission deadline 20 Jun 2026 | Viewed by 40 | Submission Open
Keywords: EVT (endovascular stroke treatment); thromboaspiration; thrombectomy; tandem lesion; rescue stenting; ICAD
(This special issue belongs to the Section Clinical Neurology)
Current Challenges and Innovations in the Treatment of Pancreatitis
edited by Nirav Thosani and Vaibhav Wadhwa
submission deadline 20 Jun 2026 | Viewed by 38 | Submission Open
Keywords: pancreatitis; acute; chronic; biomarkers; endoscopic therapy; minimally invasive interventions; fibrosis; AI modeling
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Current Concepts and Emerging Treatments in Allergic Rhinitis
edited by
submission deadline 20 Jun 2026 | Viewed by 35 | Submission Open
Keywords: rhinitis; allergic; molecular targeted therapy; cryotherapy; treatment outcome
(This special issue belongs to the Section Otolaryngology)
Current Practices and Future Challenges in Organ Transplantation
edited by and Mackenzie Morris
submission deadline 20 Jun 2026 | Viewed by 34 | Submission Open
Keywords: liver transplantation; kidney transplantation; pancreas transplantation; xenotransplantation; immunosuppression; robotic surgery; disparities; machine perfusion; organ preservation; organ allocation
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
New Insights into Transcatheter Mitral Valve Therapy
edited by Antonio Sisinni and
submission deadline 20 Jun 2026 | Viewed by 34 | Submission Open
Keywords: mitral regurgitation; transcatheter mitral valve therapy; TEER; TMVR; MitraClip; pascal; valve-in-valve; multimodality imaging; outcomes; structural heart interventions
(This special issue belongs to the Section Cardiovascular Medicine)
Oral Surgery: Recent Advances and Future Perspectives submission deadline 22 Jun 2026 | 1 articles | Viewed by 4565 | Submission Open
Keywords: oral surgery; implant dentistry; atrophic jaws; bone regeneration; digital dentistry
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Ablation, Embolization, and Stenting: Current Trends in Interventional Radiology
edited by Praveen Peddu
submission deadline 22 Jun 2026 | 1 articles | Viewed by 981 | Submission Open
Keywords: interventional radiology; ablation; embolization; stenting; minimally invasive therapy
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Clinical Advances and New Perspectives in the Diagnosis and Treatment of Schizophrenia
edited by Pierre S. Chue and Oloruntoba J. Oluboka
submission deadline 22 Jun 2026 | Viewed by 54 | Submission Open
Keywords: psychopharmacology; schizophrenia; long-acting injectable therapy; recovery; team approach to care; integrated care; clozapine; habilitation; rehabilitation; early intervention
(This special issue belongs to the Section Mental Health)
Clinical Insights and Challenges into Cognitive and Mental Health in Older Adults
edited by Dariusz Krok
submission deadline 23 Jun 2026 | 1 articles | Viewed by 407 | Submission Open
Keywords: clinical insights; cognitive and mental health; older adults; psychosomatic interventions; person-centered care
(This special issue belongs to the Section Mental Health)
Managements of Venous Thromboembolism submission deadline 24 Jun 2026 | 4 articles | Viewed by 3208 | Submission Open
Keywords: venous thromboembolism; deep vein thrombosis; pulmonary embolism; anticoagulation therapy; direct oral anticoagulants; risk stratification; bleeding risk; artificial intelligence; personalized medicine
(This special issue belongs to the Section Vascular Medicine)
Headache: Updates on the Assessment, Diagnosis and Treatment submission deadline 25 Jun 2026 | 7 articles | Viewed by 14119 | Submission Open
Keywords: headache; migraine; tension-type headache; cervicogenic headache; therapeutic exercise
(This special issue belongs to the Section Clinical Neurology)
Oral Health and Dental Care: Current Advances and Future Options
edited by , and Alessia Bramanti
submission deadline 25 Jun 2026 | 4 articles | Viewed by 11324 | Submission Open
Keywords: oral health; dental care; technologies; innovation; dental materials
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Innovations in Maxillofacial Surgery
edited by , and Ignacio Navarro Cuéllar
submission deadline 25 Jun 2026 | 5 articles | Viewed by 9272 | Submission Open
Keywords: orthognathic surgery; sleep apnea; 3D technologies; regenerative medicine; reconstructive surgery; facial trauma; minimally invasive surgery; oncology
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Recent Research Progress in Pediatric Orthopedic Surgery
edited by and Madeleine Willegger
submission deadline 25 Jun 2026 | 4 articles | Viewed by 6157 | Submission Open
Keywords: pediatric orthopedics; deformity correction; pediatric hip; pediatric trauma; basic research in pediatric orthopedics; clubfoot; pediatric foot and ankle deformities; pediatric hand
(This special issue belongs to the Section Clinical Pediatrics)
Exploring Artificial Intelligence in Precision Medicine for Gastrointestinal Diseases
edited by Vincenzo Davide Palumbo
submission deadline 25 Jun 2026 | 3 articles | Viewed by 5283 | Submission Open
Keywords: cholangiocarcinoma; biliary tree stenoses; colorectal cancer; endoscopic image analysis; IBD; gastrointestinal disorders
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Advancements in Emergency Medicine Practices and Protocols
edited by Vincenzo G. Menditto and Beatrice Gasperini
submission deadline 25 Jun 2026 | 4 articles | Viewed by 5000 | Submission Open
Keywords: emergency; pulmonary embolism; trauma; management; guidelines; frailty; emergency department observation unit
(This special issue belongs to the Section Emergency Medicine)
Anesthesia and Intensive Care in Orthopedic and Trauma Surgery
edited by Liliana Mirea, Răzvan Ene and Cristian Cobilinschi
submission deadline 25 Jun 2026 | 2 articles | Viewed by 4744 | Submission Open
Keywords: opioid sparing analgetic technique; pain management; perioperative medicine; perioperative cognitive disfunction; delirium
(This special issue belongs to the Section Intensive Care)
Clinical Advances in Radiation Therapy for Cancers submission deadline 25 Jun 2026 | 3 articles | Viewed by 4443 | Submission Open
Keywords: radiation oncology; radiotherapy; cancer radiotherapy; cancer radiation therapy; radiobiology; predictive and prognostic biomarkers; cancer treatment; heavy ions radiation oncology; protontherapy; cancer biolology
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Advances in Gastroenterology and Hepatology: Bridging Basic Science, Clinical Insights, and Translational Medicine submission deadline 25 Jun 2026 | 2 articles | Viewed by 3164 | Submission Open
Keywords: hepatology; gastroenterology; IBD; IBS; MASLD; liver cirrhosis; artificial intelligence; disorders of gut– brain interaction; cancer; gut microbiota; diagnosis; management
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Aspects of Cardiac Arrhythmias and Arrhythmogenic Disorders
edited by and Jakub Baran
submission deadline 25 Jun 2026 | 3 articles | Viewed by 2467 | Submission Open
Keywords: non-invasive arrhythmia assessment; electrocardiography; invasive arrhythmia assessment; invasive electrophysiology; catheter ablation; implantable devices; rare diseases and arrhythmias; arrhythmia risk stratification; genetics aspects of arrhythmogenesis; channelopathy
(This special issue belongs to the Section Cardiology)
Advances in Anterior Segment Surgery: Second Edition
edited by
submission deadline 25 Jun 2026 | 2 articles | Viewed by 2076 | Submission Open
Keywords: lenticule-based surgery; surface ablations; blended vision treatments with laser refractive surgery; corneal inlay procedures; presbyopia management with monovision laser vision correction; refractive lens exchange; premium presbyopia-correcting intraocular lens; refractive solutions for keratoconics; cataract surgery; corneal transplant; biometry
(This special issue belongs to the Section Ophthalmology)
Innovations and Future Directions in Valvular Heart Disease: Imaging, Technology, and Translational Research
edited by , Muhammed Gerçek and Felix Rudolph
submission deadline 25 Jun 2026 | 3 articles | Viewed by 1708 | Submission Open
Keywords: prosthetic heart valve; heart valve pathophysiology; structural heart valve interventions; echocardiographic assessment; cardiovascular imaging; valvular heart disease; valvular regurgitation; valvular stenosis; minimally invasive surgery; concomitant valve disease
(This special issue belongs to the Section Cardiology)
Advances and Innovations in Hand Surgery
edited by , Jason Wink and Anthony Archual
submission deadline 25 Jun 2026 | 2 articles | Viewed by 1185 | Submission Open
Keywords: hand surgery; peripheral nerve surgery; shared decision making; microsurgery; arthritis; compression neuropathy; carpal tunnel; cubital tunnel
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Joint Repair and Replacement: Current Challenges and Opportunities
edited by Bartosz Gonera and Kacper Ruzik
submission deadline 25 Jun 2026 | 1 articles | Viewed by 1031 | Submission Open
Keywords: orthopedic biomechanics; knee injuries; joint replacement; anterior cruciate ligament; arthroscopy; sports medicine; prosthetic implants
(This special issue belongs to the Section Orthopedics)
Advancing Neonatal Seizures and Epilepsy: New Perspectives and Interventions
edited by and Gaetano Cantalupo
submission deadline 25 Jun 2026 | 1 articles | Viewed by 683 | Submission Open
Keywords: neonatal seizures; neonatal epilepsy; neonatal EEG; automated EEG analysis; neonatal brain monitoring; genetic; precision medicine; genetic epilepsies; genome; exome
(This special issue belongs to the Section Clinical Pediatrics)
Advanced Image-Enhanced Endoscopy and Colonoscopy
edited by , and Simona Di Caro
submission deadline 25 Jun 2026 | Viewed by 182 | Submission Open
Keywords: gastrointestinal endoscopy; colorectal cancer; endoscopic screening; artificial intelligence; chromoendoscopy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Myocardial Infarction: Clinical Management and Future Options
edited by
submission deadline 25 Jun 2026 | Viewed by 180 | Submission Open
Keywords: myocardial infarction; percutaneous coronary intervention; optimal medical therapy; clinical outcomes; cardiogenic shock; mechanical cardiac support device
(This special issue belongs to the Section Cardiology)
IgA Nephropathy: Clinical Updates and Prospects
edited by
submission deadline 25 Jun 2026 | Viewed by 163 | Submission Open
Keywords: pathogenesis of IgA nephropathy; novel therapies; role of complement system; risk factors for disease progression; proteomic approach; serologic biomarkers; histological classification
(This special issue belongs to the Section Nephrology & Urology)
Clinical Advances of Aesthetic Plastic Surgery and Aesthetic Medicine
edited by Valentina Pinto and Rosalba Russo
submission deadline 25 Jun 2026 | Viewed by 163 | Submission Open
Keywords: aesthetic plastic surgery; aesthetic medicine; emerging technologies and devices in aesthetics; regenerative medicine and surgery; vulvovaginal surgery; complications in aesthetic medicine
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Multidisciplinary Care in Severe Traumatic Brain Injury Across the Continuum of Care: Acute, Rehabilitative, and Chronic Management
edited by Ryan Martin, Davin Quinn and Nicholas Race
submission deadline 25 Jun 2026 | Viewed by 116 | Submission Open
Keywords: severe traumatic brain injury; multidisciplinary; rehabilitation; advance practice providers; ancillary health; therapy; neuropsychology; nutrition
(This special issue belongs to the Section Brain Injury)
Cardiometabolic Disease and Atherosclerosis: Epidemiology, Prevention, Diagnosis, and Clinical Treatment—2nd Edition
edited by and Konstantinos Mourouzis
submission deadline 25 Jun 2026 | Viewed by 111 | Submission Open
Keywords: atherosclerosis; obesity; cardiometabolic disease; prevention; diabetes mellitus; endothelium; arteriosclerosis; coronary artery disease
(This special issue belongs to the Section Cardiology)
Geriatric Cardiology: Clinical Advances and Comprehensive Management
edited by
submission deadline 25 Jun 2026 | Viewed by 107 | Submission Open
Keywords: geriatric assessment; management of cardiovascular disease; cardiovascular health; geriatric cardiology; frailty evaluation and management
(This special issue belongs to the Section Geriatric Medicine)
Recent Clinical Advances in Cardiac Rehabilitation: 2nd Edition
edited by
submission deadline 25 Jun 2026 | Viewed by 105 | Submission Open
Keywords: cardiac rehabilitation; kinesiotherapy; psychological support; lifestyle modifications; myocardial infarction; heart failure
(This special issue belongs to the Section Cardiology)
Diet and Nutritional Aspects in Cardiovascular-Kidney-Metabolic Diseases (CKM)
edited by Krishnaswami Vijayaraghavan
submission deadline 25 Jun 2026 | Viewed by 103 | Submission Open
Keywords: cardiovascular-kidney-metabolic diseases (CKM); obesity; diabetes and metabolic syndrome; dietary factors; nutritional aspects; food policy and food security; chronic kidney disease; heart disease; technology
(This special issue belongs to the Section Clinical Nutrition & Dietetics)
Advances in Minimally Invasive and Endoscopic Neurosurgery
edited by Shunsuke Shibao
submission deadline 25 Jun 2026 | Viewed by 94 | Submission Open
Keywords: minimally invasive; endoscopic; keyhole; endonasal; transorbital; skull base; complications; surgical outcomes; technical innovations; robotic neurosurgery
(This special issue belongs to the Section Clinical Neurology)
Oral Health and Systemic Diseases: Clinical Insights
edited by
submission deadline 25 Jun 2026 | Viewed by 83 | Submission Open
Keywords: oral health; endodontics; orthodontic; periodontal disease; dental caries
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Surgical Innovations in Pediatric Orthopedics
edited by
submission deadline 25 Jun 2026 | Viewed by 76 | Submission Open
Keywords: pediatric orthopedics; surgical innovation; growth modulation; absorbable implant; 3D printing
(This special issue belongs to the Section Orthopedics)
Bariatric Surgery: Current Status and Emerging Clinical Trends
edited by Collin E. M. Brathwaite
submission deadline 25 Jun 2026 | Viewed by 74 | Submission Open
Keywords: bariatric surgery; metabolic surgery; obesity; GLP-1 receptor agonists; robotic surgery; revisional surgery; weight regain; metabolic mechanisms; enhanced recovery; surgical innovation
(This special issue belongs to the Section General Surgery)
Upper Airway Management in Obstructive Sleep Apnea: Latest Advances and Future Perspectives
edited by Shintaro Chiba
submission deadline 25 Jun 2026 | Viewed by 68 | Submission Open
Keywords: obstructive sleep apnea (OSA); sleep surgery; upper airway stimulation (UAS); upper airway physiology
(This special issue belongs to the Section Respiratory Medicine)
Clinical Management of Traumatic Brain Injury
edited by Adam James Wells and Peter Hutchinson
submission deadline 25 Jun 2026 | Viewed by 64 | Submission Open
Keywords: traumatic brain injury; clinical management TBI; neurocritical care; neuromonitoring; trauma neurosurgery; artificial intelligence
(This special issue belongs to the Section Clinical Neurology)
Clinical Advancements in Laparoscopic Surgery for Gastrointestinal Diseases
edited by
submission deadline 25 Jun 2026 | Viewed by 63 | Submission Open
Keywords: laparoscopic surgery; minimally invasive surgery; gastrointestinal diseases; colorectal cancer; gastric cancer; robotic surgery; fluorescence imaging; endoscopic-laparoscopic hybrid surgery; surgical oncology; future perspectives
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Myopic Optic Neuropathy (MON) and Glaucomatous Optic Neuropathy (GON): Current Concepts and Clinical Implications
edited by
submission deadline 25 Jun 2026 | Viewed by 61 | Submission Open
Keywords: myopic optic neuropathy; glaucomatous optic neuropathy; tilting; axonal transport; lamina cribrosa
(This special issue belongs to the Section Ophthalmology)
Diagnosis and Management of Corneal Diseases
edited by Nicola Cardascia
submission deadline 25 Jun 2026 | Viewed by 57 | Submission Open
Keywords: corneal surgery; lamellar keratoplasty; bioengineered corneal grafts; regenerative medicine; cell-based therapies; tissue-based therapies; Intraoperative imaging; corneal wound healing; lmmune modulation; graft survival; translational research; multimodal diagnostics; clinical outcomes; corneal transparency restoration; ophthalmic surgical innovation
(This special issue belongs to the Section Ophthalmology)
Technological Advancements and Clinical Innovations in Diagnostic and Interventional Radiology: 2nd Edition submission deadline 25 Jun 2026 | Viewed by 56 | Submission Open
Keywords: artificial intelligence; radiomics; image fusion; spectral computed tomography; functional magnetic resonance im-aging; CO2 angiography; balloon-occluded transcatheter arterial chemoembolization
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Cancer Prevention and Early Detection: Epidemiological Approaches and Public Health Strategies submission deadline 25 Jun 2026 | Viewed by 53 | Submission Open
Keywords: cancer prevention; cancer screening; risk factors; cancer treatment; health information systems; cancer registry; cancer inequalities
(This special issue belongs to the Section Epidemiology & Public Health)
Human Immunodeficiency Virus: From Clinical Studies to Patient Outcomes
edited by Vítor Duque
submission deadline 25 Jun 2026 | Viewed by 53 | Submission Open
Keywords: HIV/AIDS; clinical trials; patient outcomes; clinical translational research
(This special issue belongs to the Section Infectious Diseases)
Advances in Immunohematology: From Pathophysiology to Tailored Treatments submission deadline 25 Jun 2026 | Viewed by 50 | Submission Open
Keywords: autoimmune cytopenia; hemophagocytic lymphohistiocytosis; inborn errors of immunity; lymphoproliferative diseases; malignancy; monoclonal antibodies; secondary immunodeficiency; vaccination
(This special issue belongs to the Section Immunology & Rheumatology)
Cystic Fibrosis: Management Strategies and Patient Outcomes
edited by Marta Rachel
submission deadline 25 Jun 2026 | Viewed by 45 | Submission Open
Keywords: cystic fibrosis; multidisciplinary care; personalized medicine; patient outcomes; telemedicine; pediatric pulmonology; CFTR modulators; chronic disease management
(This special issue belongs to the Section Respiratory Medicine)
Integrating Artificial Intelligence and Contextual Factors in Emergency Care
edited by Ancor Sanz-García and
submission deadline 25 Jun 2026 | Viewed by 45 | Submission Open
Keywords: emergency care; artificial intelligence; early warning systems; data-driven healthcare; predictive analytics
(This special issue belongs to the Section Emergency Medicine)
Multifactorial Causation and Therapies of Myopia: 2nd Edition submission deadline 26 Jun 2026 | 1 articles | Viewed by 1192 | Submission Open
Keywords: epidemiology; genetics; premyopia; simple and pathological myopia; orthokeratology; lenses for myopia control; blue light and red light; binocular vision and ocular optics; artificial intelligence
(This special issue belongs to the Section Ophthalmology)
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