Mesenchymal Stem Cells and Their Therapeutic Applications

Dear Colleagues,

For the past two decades, the scientific and medical communities have focused on mesenchymal stem cells (MSCs) and their potential in treating diseases. MSCs can be isolated from many adult tissues, such as bone marrow, adipose tissue, umbilical cord, and dental pulp. MSCs are very promising for regenerating tissue through their differentiation potential (myoblast, epithelial cells, neurons, beta cells), decreasing inflammatory reaction, being used as anticancer therapies, and for delivering compounds to targeted organs (nucleic acids, exogenous or endogenous proteins, drugs). MSCs can be injected, transplanted or the injection of vesicles produced by the MSCs. Improvement of their therapeutical properties still needs a lot of effort to decrease the variability among studies and to increase the positive outcomes.

This Special Issue will accept for submission original research articles, reviews, and methods from leading scientists and clinicians around the world who are studying and developing MSC-based therapy. Topics of interest include therapeutic applications of MSCs, and more specifically cell/gene therapy, exosomes and extracellular vesicles, mechanism of action, bioprinting, GMP manufacturing, and regulatory guidelines.

Dr. Joan Oliva
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Translational Medicine is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.