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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Insight into Plant Bioactive Compounds: 2nd Edition

edited by

Karolina Wojtunik-Kulesza

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1399 | Submission Open

Keywords: bioactivity; disease prevention; herbal medicines; antioxidants; qualitative analysis

(This special issue belongs to the Section Molecular Plant Sciences)

New Molecular Insights into Myeloma

edited by Kotaro Shirakawa

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1357 | Submission Open

Keywords: multiple myeloma; clonal evolution and genetic heterogeneity; epigenomic dysregulation; transcriptional reprogramming; mitochondrial dysfunction; bone marrow microenvironment; tumor microenvironment; immunotherapy resistance; drug resistance; single-cell and spatial analysis

(This special issue belongs to the Section Molecular Oncology)

Molecular Adsorption Mechanisms: Theoretical and Experimental Studies

edited by

Anna Deryło-Marczewska

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1315 | Submission Open

Keywords: adsorption processes; adsorption mechanisms; adsorption equilibria; adsorption kinetics; porous materials; structure—property relationships; theoretical and experimental analysis; environmental, analytical, biomedical and technological applications

(This special issue belongs to the Section Molecular Biophysics)

Advances in Allergen Immunotherapy: Current Concepts and Future Directions

edited by

Constantinos Pitsios

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1293 | Submission Open

Keywords: allergen immunotherapy; oral immunotherapy; Hymenoptera venom; allergy extracts; adjuvants

(This special issue belongs to the Section Molecular Immunology)

Molecular Pathogenesis, Immunobiology, and Treatment of Hematological Malignancies

edited by Won Tatsuro Jo

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1293 | Submission Open

Keywords: hematological malignancies; molecular pathogenesis; tumor microenvironment; immunogenomics; clonal evolution; biomarkers; immune monitoring; T-cell receptor repertoire; targeted therapy; immunotherapy

(This special issue belongs to the Section Molecular Immunology)

Tumor Viruses: Infection, Carcinogenesis, and Treatment

edited by

Sherif T.S. Hassan

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1290 | Submission Open

Keywords: tumor viruses; viral oncogenesis; EBV, HPV, KSHV, HBV, HCV, HTLV-1, and MCPyV; virus-associated cancers; merging oncoviruses; viral latency; immune evasion; antiviral therapy; immunotherapy; cancer vaccines; gene-editing technologies

(This special issue belongs to the Section Molecular Microbiology)

Cardiovascular and Metabolic Sequelae of Peripheral Artery Disease: From Mechanisms to Therapeutic Targets

edited by

Tzong-Shyuan Lee

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1267 | Submission Open

Keywords: peripheral artery disease (PAD); cardiometabolic complications; molecular mechanisms; endothelial dysfunction; interorgan crosstalk

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Nanoparticle–Protein Interactions: Therapeutic Approaches and Supramolecular Chemistry

edited by Rodrigo da Silva Ferreira

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1255 | Submission Open

Keywords: nanoparticle–protein interactions; nanomedicine; supramolecular chemistry; surface functionalization; protein corona; nanocarriers; biointerfaces; molecular recognition; therapeutic nanomaterials; computational nano–bio modelling

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Advances in Pathogen Interaction and Host Immunity

edited by

Karolina Kot

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1254 | Submission Open

Keywords: host–pathogen interactions; innate and adaptive immunity; pattern recognition receptors (PRRs); immune signaling pathways; cytokines and interferons; immune evasion mechanisms; molecular pathogenesis; infectious diseases

(This special issue belongs to the Section Molecular Immunology)

Molecular Characterization of Glioblastoma: Implications for Diagnosis and Personalized Treatment

edited by Madan Mohan Kwatra

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1241 | Submission Open

Keywords: glioblastoma; diagnosis; molecular characterization; personalized treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Glyco-Based Anticancer Agents

edited by Pedro Colinas

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1221 | Submission Open

Keywords: carbohydrates; cancer; Warburg effect; glycolysis; enzyme inhibitors; transporters inhibitors; docking simulations; tumor microenvironment

(This special issue belongs to the Section Biochemistry)

Current Research on Phenolic Profiles and Anti-Inflammatory Activities of Plants

edited by Chi-Rei Wu and Li-Wei Lin

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1193 | Submission Open

Keywords: plants; phenolic profiles; inflammation; cardiovascular disorders; cancer; diabetes; neurodegenerative disorders

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Host-Pathogen Interactions in Plants: Molecular Mechanisms and Sustainable Strategies

edited by Muhammad Rahil Afzal and Misbah Naz

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1162 | Submission Open

Keywords: plant immunity; plant–pathogen interactions; molecular mechanisms; effector biology; hormonal crosstalk; non-coding RNAs and epigenetics

(This special issue belongs to the Section Molecular Plant Sciences)

Extracellular Vesicles: Biomarkers and Therapeutic Carriers in Human Health and Disease

edited by

José Eduardo Vargas

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1160 | Submission Open

Keywords: extracellular vesicles; cellular senescence; autophagy; biomarkers; drug delivery; translational medicine; human disease; cell fate

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms of Hormone/Receptor System in Human Diseases

edited by Elena Zocchi,

Sonia Spinelli

and

Laura Sturla

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1158 | Submission Open

Keywords: hormone; receptor; energy metabolism; mitochondria

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

New Molecular Mechanisms and Markers in Inflammatory Disorders, 4th Edition

edited by

Elena Vianello

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1132 | Submission Open

Keywords: inflammation; inflammatory disorders; biomarkers; molecular mechanism of inflammation; molecular signaling

(This special issue belongs to the Section Molecular Immunology)

Advanced Silica-Based Materials: From Molecular Design to Sustainable Applications

edited by Marius Rǎdulescu

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1127 | Submission Open

Keywords: silica-based materials; molecular design; hybrid nanomaterials; surface chemistry; structure–property relationships; functionalized silica; sol–gel processes; molecular interactions; green synthesis; sustainable applications; nanostructured systems; catalysis and adsorption; biomedical interfaces; energy and environmental materials; molecular modeling

(This special issue belongs to the Section Molecular Nanoscience)

Non-Coding RNAs and Post-Transcriptional Modifications in Cancer

edited by

Christos K. Kontos

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1123 | Submission Open

Keywords: solid tumors; hematological malignancies; long non-coding RNAs; circular RNAs; short non-coding RNAs

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advances in Polymeric Nanomaterials in Medicine

edited by Prabhanjan Giram

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1112 | Submission Open

Keywords: nanomaterials; nanocomposites; biomolecules; nano pharmaceuticals; nanoparticles; applications of nanomaterials; nanoformulation design; characterization; nanodrug delivery system; targeted and controlled release therapies

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Atlas of Cardiac Development and Diseases

edited by

Hector Alejandro Cabrera-Fuentes

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1094 | Submission Open

Keywords: cardiac development; molecular atlas; cardiovascular disease; single cell and spatial omics; multi omics integration; gene regulatory networks; cardiac remodeling; heart failure; systems biology; artificial intelligence in cardiology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Chlorophylls and Carotenoids: Metabolism and Regulation in Plants

edited by

Shan Lu

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1075 | Submission Open

Keywords: chlorophyll; carotenoid; metabolism; regulation; evolution; coordination

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Insights into Gangliosides

edited by

Sandro Sonnino

and

Massimo Aureli

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1034 | Submission Open

Keywords: gangliosides; sphingolipids; plasma membrane; lysosomes; glycohydrolases; neurodegeneration

(This special issue belongs to the Section Molecular Neurobiology)

Oxidative Stress and Mitochondrial Dysfunction in Human Diseases

edited by Patrice X. Petit

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1017 | Submission Open

Keywords: aging; DAMPs; inflammation; Fenton reaction; ferroptosis; hydroperoxide; mitochondria; mitophagy; NIX; NLRP3; oxidized mtDNA; RIRR; superoxide anions; stem cells

(This special issue belongs to the Section Molecular Biology)

Molecular Advances in Oral and Periodontal Health

edited by

Giuseppina Malcangi

, Roxana Ioana Bordea and Grazia Marinelli

submission deadline 28 Feb 2027 | 1 articles | Viewed by 996 | Submission Open

Keywords: dental disease; dental materials; orthodontic diseases; growth factor; regenerative tissue; peritonitis; regulatory T cells; systemic disease; systemic inflammation; scaling and root planning

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Plant–Microbial Interaction

edited by

Diby Paul

submission deadline 28 Feb 2027 | 1 articles | Viewed by 975 | Submission Open

Keywords: plant microbe intractions; molecular mechanisms; microbiome dynamics; multi-omics approach; stress responses; metagenomics; rhizosphere signalling

(This special issue belongs to the Section Molecular Microbiology)

Deciphering the Molecular Mechanisms and Etiology of Thrombosis

edited by Omri Snir

submission deadline 28 Feb 2027 | 1 articles | Viewed by 946 | Submission Open

Keywords: thrombogenesis; molecular mechanisms; etiology; thrombo-inflammation; therapeutic targets; endothelial dysfunction; extracellular vesicles; coagulation; fibrinolysis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cellular Physiology and Aging: Membrane Dynamics, Intracellular Environment and Signaling Pathways

edited by

Alessia Remigante

Rossana Morabito

and Sara Spinelli

submission deadline 28 Feb 2027 | 1 articles | Viewed by 935 | Submission Open

Keywords: aging; oxidative stress; ion channels; antioxidant molecules; membrane transport systems; redox signaling; cellular senescence; inflammation; intracellular signaling pathways; mitochondrial dysfunction; bioactive compounds; cell physiology; homeostasis; longevity; age-related diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Polyendocrine-Metabolic-Ovarian Syndrome: Targeted Therapeutics and Future Perspectives

edited by Noha Shawky and

Manar A. Eissa

submission deadline 28 Feb 2027 | 1 articles | Viewed by 912 | Submission Open

Keywords: PMOS; hyperandrogenism; insulin resistance; cardiometabolic disease; inflammation; maternal-offspring; developmental origins of health and disease; aging

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Algal Stress Physiology

edited by

Zakaria Tazart

submission deadline 28 Feb 2027 | 1 articles | Viewed by 901 | Submission Open

Keywords: algae; microalgae; cyanobacteria; stress physiology; molecular mechanisms; signal transduction; gene regulation; redox homeostasis; omics technologies; environmental stress; metabolic adaptation; biotechnology

(This special issue belongs to the Section Molecular Plant Sciences)

Plant Metabolism and Genetics

edited by

Dalu Li

submission deadline 28 Feb 2027 | 1 articles | Viewed by 858 | Submission Open

Keywords: plant metabolism; genetics; genomics; multi-omics integration; secondary/specialized metabolites; biosynthetic pathways; metabolic engineering crop improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Genetic and Molecular Strategies to Soybean Improvement

edited by

Junming Sun

submission deadline 28 Feb 2027 | 1 articles | Viewed by 855 | Submission Open

Keywords: soybean; genome editing; CRISPR/Cas9; quantitative trait loci (QTL); marker-assisted selection; functional genomics; molecular breeding; crop improvement; gene expression; genetics and breeding

(This special issue belongs to the Section Molecular Plant Sciences)

Pulmonary Hypertension: From Molecular Pathophysiology to New Therapeutic Approaches

edited by Claudia Mickael

submission deadline 28 Feb 2027 | 1 articles | Viewed by 847 | Submission Open

Keywords: pulmonary hypertension; molecular pathophysiology; vascular remodelling; targeted therapies; translational research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Latest Insight into Spin and Isomerism of Organic Molecules

edited by

Chenwei Jiang

and

Le Yu

submission deadline 28 Feb 2027 | 1 articles | Viewed by 836 | Submission Open

Keywords: organic molecules; photoisomerization; spin states; isomerism; spin crossover; conformational dynamics; quantum chemistry; radical chemistry; singlet fission

(This special issue belongs to the Section Molecular Biophysics)

Pathophysiology of Preeclampsia and Gestational Diabetes: Shared Molecular Mechanisms in Pregnancy-Related Disorders

edited by Tamara Nikolic Turnic

submission deadline 28 Feb 2027 | Viewed by 834 | Submission Open

Keywords: preeclampsia; molecular mechanism; mechanism of preventive/curative strategies; placenta dysfunction

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Immunological Regulation as Determinant of Outcomes in Critically Sick Patients

edited by

Krzysztof Laudanski

submission deadline 28 Feb 2027 | 1 articles | Viewed by 823 | Submission Open

Keywords: critical illness; outcome; immune system; inflammation; homeostasis; epigenetic; microbiome; central nervous system; dysregulation; recovery

(This special issue belongs to the Section Molecular Immunology)

Omics-Driven Advances in Plant Abiotic Stress Tolerance

edited by

Kincső Decsi

submission deadline 28 Feb 2027 | 1 articles | Viewed by 823 | Submission Open

Keywords: omics; abiotic stressors; prevention; cellular biochemical changes; individual or genome-wide analyses

(This special issue belongs to the Section Molecular Plant Sciences)

Antioxidants and Redox Biomarkers: Beneficial and Harmful Effects on Human Health

edited by

Ramona D'Amico

submission deadline 28 Feb 2027 | 1 articles | Viewed by 821 | Submission Open

Keywords: antioxidants; redox homeostasis; oxidative stress; redox biomarkers; redox balance; molecular pathways; human health

(This special issue belongs to the Section Molecular Biology)

Recent Developments in Bioactive and Functional Nanomaterials

edited by Mónica Rosalía Jaime-Fonseca, José Abraham Balderas López and Miguel Angel Aguilar Méndez

submission deadline 28 Feb 2027 | 1 articles | Viewed by 820 | Submission Open

Keywords: bioactives; nanostructured materials; nanoparticles; nanofibers; nanomedicine drug delivery; biosensors; smart food packaging; functional foods; sustainable agriculture

(This special issue belongs to the Section Molecular Nanoscience)

Hepatocellular Carcinoma: From Pathophysiology to Innovative Therapeutic Approaches

edited by Andrea Martini

submission deadline 28 Feb 2027 | Viewed by 799 | Submission Open

Keywords: liver carcinogenesis; tumor microenvironment; immune surveillance; fibrogenesis; inflammation

(This special issue belongs to the Section Molecular Oncology)

Cancer Stem Cells: Molecular Mechanisms and Therapeutic Targeting

edited by Pablo Pérez-Moreno

submission deadline 28 Feb 2027 | 1 articles | Viewed by 790 | Submission Open

Keywords: cancer stem cells; CSCs clinical biomarkers; CSCs as therapeutic targets; cancer cell biology of CSCs; prognosis and CSCs; molecular biology and CSCs

(This special issue belongs to the Section Molecular Oncology)

Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers, 4rd Edition

edited by

Andrzej Kutner

Geoffrey Brown

and Enikö Kallay

submission deadline 28 Feb 2027 | 1 articles | Viewed by 790 | Submission Open

Keywords: drug design and discovery antimicrobial drugs; antiviral drugs; antibiotics; cancer prevention and treatment molecular modeling; molecular mechanisms; crystallography preclinical studies; pharmacokinetics; pharmacodynamics; pharmacognosy drug-protein interactions nuclear receptors; receptor agonists and antagonists; stem cells; activity profiling; vaccines; markers; and diagnostics drug carriers; dosage form; anti-crystal engineering; nanoparticles; dissolution testing

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Insights into Rhizospheric Microbial Interactions

edited by

Jelena Lozo

submission deadline 28 Feb 2027 | 1 articles | Viewed by 779 | Submission Open

Keywords: plant–microorganism interactions; rhizosphere community; secretory systems; secondary metabolites; volatile compounds

(This special issue belongs to the Section Molecular Microbiology)

Protein Structure, Function and Design

edited by Tatiana de Arruda Campos Brasil de Souza

submission deadline 28 Feb 2027 | 1 articles | Viewed by 753 | Submission Open

Keywords: protein structure; protein function; protein design; protein engineering; structural biology; computational prediction; molecular dynamics; protein-protein interactions; therapeutic proteins; structure-function relationship

(This special issue belongs to the Section Biochemistry)

Molecular and Adaptive Mechanisms in Plant Genetics

edited by

Gennaro Lettieri

submission deadline 28 Feb 2027 | 1 articles | Viewed by 748 | Submission Open

Keywords: forest genetics; breeding techniques; molecular breeding

(This special issue belongs to the Section Molecular Plant Sciences)

Latest Advances in Pituitary Endocrinology

edited by

Antonio M. Picó

and Cristina Lamas

submission deadline 28 Feb 2027 | 1 articles | Viewed by 748 | Submission Open

Keywords: pituitary tumors; hypopituitarism; growth and puberty disorders; acromegaly; Cushing’s disease and silent corticotroph tumors; silent pituitary tumors; hypophysitis; molecular endocrinology and transcription factors; hormone resistance; precision endocrinology

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Novel Heterocyclic Bioactive Compounds: Design, Synthesis and Biological Evaluation

edited by

Lilia Matei

submission deadline 28 Feb 2027 | Viewed by 736 | Submission Open

Keywords: heterocyclic compounds; drug design; medicinal chemistry; bioactive molecules; structure–activity relationships; synthetic methodologies; molecular mechanisms of action; pharmacological evaluation; therapeutic agents

(This special issue belongs to the Section Biochemistry)

Photosensitizers for Photodynamic Therapy: From Molecular Design to Application

edited by

Carlos Monteiro

M. Amparo F. Faustino

and

Leandro M. O. Lourenço

submission deadline 28 Feb 2027 | Viewed by 709 | Submission Open

Keywords: photodynamic therapy (PDT); photosensitizers (PS); reactive oxygen species (ROS); molecular design; nanocarriers; porphyrins and analogs; targeted drug delivery; translational medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular and Translational Research on Late-Life Cognitive and Neuropsychiatric Disorders

edited by

Ioannis Liampas

submission deadline 28 Feb 2027 | 1 articles | Viewed by 701 | Submission Open

Keywords: dementia; Alzheimer’s disease; mild cognitive impairment; mild behavioral impairment; movement disorders; Parkinson’s disease; biomarkers; neurogenetics; molecular research

(This special issue belongs to the Section Molecular Neurobiology)

Viral Infection: Molecular Mechanisms and Vaccine Approaches

edited by

Ismaïl Moukadiri

submission deadline 28 Feb 2027 | 1 articles | Viewed by 674 | Submission Open

Keywords: viral infection; molecular virology; molecular mechanisms; antigen engineering; next-generation vaccine design

(This special issue belongs to the Section Molecular Immunology)

Molecular Mechanisms in Action of Hormones

edited by

Chirine Toufaily

submission deadline 28 Feb 2027 | Viewed by 636 | Submission Open

Keywords: G-protein coupled receptors; bias signaling; neuromodulators; nuclear receptors; small molecules; hormonal crosstalk; endocrine stressors; cell-cell communication; gene expression; spatial transcriptomics

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Displaying special issue 2351-2400 on page 48 of 64.

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