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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Advances in Cancer Stem Cell Research: 2nd Edition

edited by

Tomoyasu Sugiyama

submission deadline 20 Jul 2025 | Viewed by 377 | Submission Open

Keywords: cancer stem cell; biomarker; signaling; cancer-associated fibroblast; artificial intelligence; cell therapy; antibody therapy; cell therapy; gene expression

(This special issue belongs to the Section Molecular Oncology)

Molecular Precision Medicine: Unraveling Disease Mechanisms, Targeted Therapeutics and Innovative Diagnostics

edited by

Shairaz Baksh

submission deadline 20 Jul 2025 | Viewed by 374 | Submission Open

Keywords: molecular precision medicine; mass spectrometry; biomarkers; cancer; inflammation; neuroinflammation; neurodegenerative; diabetes; cardiometabolic disorders; mental health

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Chronic Lymphocytic Leukemia: Molecular Pathologies and Therapeutic Strategies

edited by Tang Her Jaing

submission deadline 20 Jul 2025 | Viewed by 370 | Submission Open

Keywords: chronic lymphocytic leukemia; genomic landscapes; precision medicine; clinical trials; biomarker

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Pathophysiology of Multiple Sclerosis and Neuroinflammation

edited by

Fabrizio Michetti

submission deadline 20 Jul 2025 | Viewed by 342 | Submission Open

Keywords: multiple sclerosis (MS); autoimmune diseases; encephalomyelitis; neuroinflammation; central nervous system (CNS); autoimmunity and neurodegeneration; molecular basis of immune mechanisms

(This special issue belongs to the Section Molecular Neurobiology)

Redox Systems in Humans, Animals, Plants and Aquatic Ecosystems and Their Microbiomes

edited by

Eugenio Luigi Iorio

submission deadline 20 Jul 2025 | Viewed by 341 | Submission Open

Keywords: redox systems; aging and disease; nutraceuticals; probiotics; animals; plants; aquatic ecosystems; microbiomes

(This special issue belongs to the Section Molecular Biology)

Molecular Research and Insight in Neurotransmission and Neuromodulation

edited by Miklos Jaszberenyi

submission deadline 20 Jul 2025 | Viewed by 335 | Submission Open

Keywords: histology; microanatomy; morphology; molecular biology; neurotransmitter; neuromodulator; neuropeptide; neurohormone; nervous system

(This special issue belongs to the Section Molecular Neurobiology)

Cutting-Edge Advances in Natural Bioactive Compounds

edited by

Luisa M. P. F. Amaral

and

Romeu A. Videira

submission deadline 20 Jul 2025 | Viewed by 319 | Submission Open

Keywords: natural bioactive compounds; discovery and isolation; chemical characterization; biological activities; mechanisms of action; pharmaceuticals; nutraceuticals; agricultural applications; cosmetic innovations

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Nanomaterials for Biomedical and Environmental Applications

edited by

Łukasz Laskowski

submission deadline 20 Jul 2025 | Viewed by 319 | Submission Open

Keywords: nanomaterials; functional materials; biomaterials; nanocomposites; biocidal materials; environmental protection; nanostructured materials; mesoporous materials

(This special issue belongs to the Section Molecular Nanoscience)

Hormone Metabolism and Signaling in Human Health and Disease

edited by

Kuo-Hu Chen

submission deadline 20 Jul 2025 | Viewed by 319 | Submission Open

Keywords: hormone metabolism; signaling pathways; pathophysiology; molecular and cellular biology; diseases originating from hormone disorders; hormonal therapy

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Protease and Carbonic Anhydrase Inhibitors: 3rd Edition

edited by

Alessio Nocentini

submission deadline 20 Jul 2025 | Viewed by 315 | Submission Open

Keywords: carbonic anhydrase; protease; inhibitor; antiviral drug; antitumor drug; drug design; serine protease; metalloprotease; aspartic protease

(This special issue belongs to the Section Biochemistry)

Molecular Mechanisms of Bone Injury and Bone Tissue Regeneration

edited by Nasim Golafshan

submission deadline 20 Jul 2025 | Viewed by 314 | Submission Open

Keywords: bone formation; osteoblast diffrentiation; cell-based materials

(This special issue belongs to the Section Materials Science)

Molecular Mechanisms of Bone Development and Differentiation in Health and Disease

edited by

Cristina Sánchez-De-Diego

submission deadline 20 Jul 2025 | Viewed by 308 | Submission Open

Keywords: bone differentiation; signaling pathways; bone diseases; bone formation; osteoblast; osteocyte; osteoclast

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Endocannabinoids, Cannabinoids and Psychiatry: Biological Mechanisms—3rd Edition

edited by

Aron Weller

and Nicholas V. DiPatrizio

submission deadline 20 Jul 2025 | Viewed by 304 | Submission Open

Keywords: endocannabinoids; cannabinoids; psychiatry; neural mechanisms; molecular mechanisms; epigenetics; imaging; psychopathology; stress

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research on Bioinformatics Analysis of the Gut Microbiome and Transcriptome

edited by

Chenkai Ma

submission deadline 20 Jul 2025 | Viewed by 302 | Submission Open

Keywords: gut health; gut microbiome; transcriptome; multi-omics; bioinformatics; bowel cancer; gut infections; inflammatory bowel diseases

(This special issue belongs to the Section Molecular Informatics)

Drug Therapy of Systemic Lupus Erythematosus

edited by Dionysis Nikolopoulos

submission deadline 20 Jul 2025 | Viewed by 301 | Submission Open

Keywords: systemic lupus erythematosus; treatment; drugs; tailored strategies; precision medicine; biologics; cell therapy; randomized clinical trials

(This special issue belongs to the Section Molecular Pharmacology)

Editorial Board Member's Collection Series: The Memory of the Immune Cells

edited by

Malgorzata Kloc

and

Jacek Z. Kubiak

submission deadline 20 Jul 2025 | Viewed by 300 | Submission Open

Keywords: immunological memory; innate immune memory; dendritic cells; natural killer cells; macrophage memory

(This special issue belongs to the Section Molecular Immunology)

Reproductive Toxicity of Chemicals

edited by

Maria Laura Zenclussen

submission deadline 20 Jul 2025 | Viewed by 299 | Submission Open

Keywords: reproductive health; fertility; anthropogenic chemicals; impaired fertility; reproductive toxicity; embryo; toxicants; hormone disruption; chemical exposure

(This special issue belongs to the Section Molecular Toxicology)

Exploring Cancer Molecular Mechanisms with AI

edited by Juan Jose Lozano and Julia Sidorova

submission deadline 20 Jul 2025 | Viewed by 294 | Submission Open

Keywords: cancer; biomarker; deep learning; molecular signature; omics data; pharmacogenomics; artificial intelligence; bioinformatics

(This special issue belongs to the Section Molecular Informatics)

Stem Cell Therapy for Neurological Disorders

edited by Gabriele Bonaventura

submission deadline 20 Jul 2025 | Viewed by 292 | Submission Open

Keywords: neurodegenerative disease; cell therapy; stem cells; induced pluripotent stem cells; disease modeling; drug target validation

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Bioactive Nanoparticles and Cancer: From Biomarker Discovery to Drug Delivery

edited by Paola Gagni

submission deadline 20 Jul 2025 | Viewed by 290 | Submission Open

Keywords: nanoparticles; extracellular particles; extracellular vesicles; nanocarriers; drug delivery; biosensing; biomarker discovery; nanomedicine; liquid biopsy; advanced diagnostics; cancer

(This special issue belongs to the Section Molecular Nanoscience)

Enhanced Anticancer Properties of Natural Products

edited by

Won Sup Lee

and

Eun Joo Jung

submission deadline 20 Jul 2025 | Viewed by 284 | Submission Open

Keywords: natural products; anticancer properties; chemotherapeutc agent; combination treatment; enhanced anticancer mechanism; signal transduction mediators; inhibitor effect; drug resistance; chemotherapy

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Insights into How Electromagnetic Fields Affect Human Immunity and Metabolic Activity

edited by Jolanta Kaszuba-Zwoińska

submission deadline 20 Jul 2025 | Viewed by 284 | Submission Open

Keywords: electromagnetic fields; metabolism; innate and acquired immunity; cell viability; cell secretory activity; cell death types; pathogenesis of diseases

(This special issue belongs to the Section Molecular Biology)

Acute Kidney Injury: From Molecular Pathology to Therapies

edited by

José António Lopes

submission deadline 20 Jul 2025 | Viewed by 282 | Submission Open

Keywords: acute kidney injury; acute kidney disease; biomarkers; phenotypes; pathogenesis; risk identification; prognostic impact; therapeutic approach

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Herpes Simplex Virus: Immunity, Pathogenicity, Immune Escape Mechanisms, and Antiviral Strategies

edited by

Maria Teresa Sciortino

submission deadline 20 Jul 2025 | Viewed by 275 | Submission Open

Keywords: herpes simplex virus (HSV); latency; immune evasion; tegument proteins; epigenetic mechanisms; viral pathogenesis; antiviral strategies; molecular mechanisms; therapeutic interventions

(This special issue belongs to the Section Molecular Immunology)

Dietary Polyphenols for Improving Gut Health

edited by Andreia Gomes

submission deadline 20 Jul 2025 | Viewed by 269 | Submission Open

Keywords: microbiota diversity; gut health; polyphenols; polyphenol bioavailability; immune function; inflammation; therapeutic potential of polyphenols; host health

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Diagnosis and Treatment of Migraine

edited by

Fabiola Dach

submission deadline 20 Jul 2025 | Viewed by 266 | Submission Open

Keywords: migraine; pathophysiology; diagnostics; therapy; molecular mechanisms

(This special issue belongs to the Section Molecular Biology)

Monoamine Signalling Pathways as a Target for Pathomechanism of Mental Disorders and Pharmacotherapy

edited by

Agnieszka Zelek-Molik

submission deadline 20 Jul 2025 | Viewed by 264 | Submission Open

Keywords: monoaminergic system; psychiatric disorders; neurotransmission regulation; biomarkers; novel therapies

(This special issue belongs to the Section Molecular Neurobiology)

Progress in Fighting Inflammation to Reduce Life-Threatening Organ Dysfunction

edited by

Narcis Tribulova

submission deadline 20 Jul 2025 | Viewed by 263 | Submission Open

Keywords: inflammasomopathy; NLRP3; nod-like receptor protein 3 inflammasome; anti-inflammatory; organ dysfunction; organ injury; organ failure

(This special issue belongs to the Section Molecular Biology)

Roles of Neutrophils in Autoimmune Diseases and Cancers

edited by

Jasmin Knopf

submission deadline 20 Jul 2025 | Viewed by 252 | Submission Open

Keywords: neutrophils; neutrophil extracellular traps (NETs); autoimmunity; autoimmune disease(s); cancer; oncology

(This special issue belongs to the Section Molecular Immunology)

Recent Research of Nanomaterials in Molecular Science: 2nd Edition

edited by

Giovanna Iezzi

submission deadline 20 Jul 2025 | Viewed by 250 | Submission Open

Keywords: nanomaterials; medical research; synthesis and characterization; molecular formula; molecular dynamics; molecular imaging; cell signaling; cellular metabolism; tissue regeneration; biocompatibility; molecular biology; nanomedicine; functional nanomaterials; drug and gene delivery; tissue engineering; cancer therapy

(This special issue belongs to the Section Molecular Nanoscience)

The Role of Immunocytes in Cancer and New Insights into Immunotherapy

edited by Ida Franiak-Pietryga

submission deadline 20 Jul 2025 | Viewed by 247 | Submission Open

Keywords: T cells; B cells; NK cells; adoptive cell therapy; cancer; immunotherapy; checkpoint inhibitors

(This special issue belongs to the Section Molecular Immunology)

Computational Genomics and Bioinformatics in Microbiology

edited by

Andreas Martin Lisewski

submission deadline 20 Jul 2025 | Viewed by 243 | Submission Open

Keywords: computational microbial genomics; comparative genomics; structural genomics; functional genomics; genomic data bioinformatics

(This special issue belongs to the Section Molecular Informatics)

Advances in Regenerative Medicine, Organ Bioengineering and Transplantation

edited by

Dorota Latek

submission deadline 20 Jul 2025 | Viewed by 240 | Submission Open

Keywords: regenerative medicine; organ bioengineering; transplantation; allografting; stem cells; drug discovery; immunosuppression; xenotransplantation; organogenesis; biomaterials

(This special issue belongs to the Section Molecular Immunology)

Drug Delivery Systems and Treatment of Human Diseases: Prospects and Challenges

edited by

Aruna Sharma

submission deadline 20 Jul 2025 | Viewed by 224 | Submission Open

Keywords: nanodrug delivery; blood– brain barrier; antibodies therapy; molecular mechanism; neuroprotection

(This special issue belongs to the Section Molecular Pharmacology)

Squamous Cell Carcinoma: From Molecular Mechanisms to Therapeutics

edited by

Nerina Denaro

submission deadline 20 Jul 2025 | Viewed by 218 | Submission Open

Keywords: squamous cell carcinoma; immunotherapy; melanoma; non-melanoma

(This special issue belongs to the Section Molecular Oncology)

Pathogenic Mechanisms of Candida auris

edited by

Anastasia Spiliopoulou

submission deadline 20 Jul 2025 | Viewed by 213 | Submission Open

Keywords: C. auris; antifungal resistance; immune evasion

(This special issue belongs to the Section Molecular Microbiology)

Advances in Plant Protein and Enzyme Inhibitors

edited by Yan Zhang

submission deadline 20 Jul 2025 | Viewed by 212 | Submission Open

Keywords: plant proteins; active substances; bioactive compounds; enzyme inhibitors

(This special issue belongs to the Section Molecular Plant Sciences)

Innovative Molecular Diagnostic and Therapeutic Strategies for Biofilm-Associated Periprosthetic Joint Infections

edited by

Bart C.H. van der Wal

submission deadline 20 Jul 2025 | Viewed by 193 | Submission Open

Keywords: periprosthetic joint infections; biofilm; antimicrobial resistance; diagnosis; therapy; nanotechnology; antibody; ap-tamer; prosthetic materials

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Neuroimmune Regulation of Acute and Chronic Pain

edited by Karen M. Wagner

submission deadline 20 Jul 2025 | Viewed by 191 | Submission Open

Keywords: acute pain; chronic pain; central sensitization; neuroinflammation; neuroimmunity; neurovascular coupling; cytokines; chemokines; catacholamines; stress

(This special issue belongs to the Section Molecular Neurobiology)

Pediatric Gastrointestinal and Biliary Diseases: From Molecular Basis to Therapy

edited by

Consolato M. Sergi

submission deadline 20 Jul 2025 | Viewed by 144 | Submission Open

Keywords: pediatrics; gastroenterology; biliary; therapy; genetics; biology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Biomarker Discovery for Rare Diseases

edited by

Bridget E. Bax

submission deadline 20 Jul 2025 | Viewed by 144 | Submission Open

Keywords: biomarker; rare diseases; pathological processes; cystic fibrosis; Duchenne muscular dystrophy; Ehlers-Danlos syndrome; haemophilia; sickle cell disease; primary biliary cholangitis; fabry disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biomaterials and Antibacterial Materials for Medical Applications

edited by

Shixiong Yi

submission deadline 20 Jul 2025 | Viewed by 113 | Submission Open

Keywords: biomaterial science; photodynamic antibacterial materials; photothermal antibacterial materials; advanced antibacterial materials; antimicrobial nanostructured materials; polymer-based biomaterials; infected wound dressings

(This special issue belongs to the Section Materials Science)

Molecular Mechanisms and Therapies of Gastrointestinal Cancer

edited by

Donatella Delle Cave

submission deadline 20 Jul 2025 | Viewed by 109 | Submission Open

Keywords: tumor microenvironment; therapy resistance; genetic mutations; oncogenes; molecular diagnostics

(This special issue belongs to the Section Molecular Oncology)

Multiple Sclerosis: From Molecular Mechanisms to Pathophysiology

edited by

Paolo Ragonese

submission deadline 20 Jul 2025 | Viewed by 106 | Submission Open

Keywords: multiple sclerosis; pathogenesis; blood– brain barrier; cellular pathways; neurodegeneration; biomarkers; gene– environment interaction; astrocytes; glia

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Studies of Bone Biology and Bone Tissue: 2nd Edition

edited by

Giovanna Iezzi

submission deadline 20 Jul 2025 | Viewed by 97 | Submission Open

Keywords: bone; stem cells; immunomodulation; biomaterials; bone regeneration; bone repair; bone diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Motor Neuron Diseases: From Molecular Pathology to Novel Therapeutic Approaches

edited by

Emanuele D'Amico

submission deadline 20 Jul 2025 | Viewed by 86 | Submission Open

Keywords: amyotrophic lateral sclerosis; motor neuron disease; genomic; proteomic; neuroinflammation; oxidative stress; calpain-2; mRNA; T-reg; SOD1

(This special issue belongs to the Section Molecular Neurobiology)

The Role of Bioactive Natural Products and in Human Health

edited by

Eleonora Di Salvo

submission deadline 20 Jul 2025 | Viewed by 77 | Submission Open

Keywords: bioactive compound; human health; functional foods; nutraceutical products; food toxicology; antioxidant properties; anti-inflammation; antimicrobial molecules

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Issues in Optic Neuropathy

edited by

Nitza Goldenberg-Cohen

submission deadline 20 Jul 2025 | Viewed by 67 | Submission Open

Keywords: optic neuropathy; neuroprotection; glaucoma induced neuropathy; molecular pathways; novel therapeutics strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cardiovascular Diseases at the Molecular Level: Innovations in Research and Therapy

edited by Stefan Cristian Vesa

submission deadline 20 Jul 2025 | Viewed by 30 | Submission Open

Keywords: cardiovascular disease; molecular mechanisms; novel therapy; gene therapy; personalized medicine epigenetics; regenerative medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Male Genitourinary Tumors: Molecular Mechanisms and Potential Therapeutic Targets

edited by

Luigi Cormio

and

Francesca Sanguedolce

submission deadline 25 Jul 2025 | 5 articles | Viewed by 8055 | Submission Open

Keywords: prostate cancer; bladder cancer; biomarkers; molecular mechanisms; therapeutic targets; translational research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 1351-1400 on page 28 of 68.

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