Roles of Phytochemicals in Molecular Signaling Networks
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 3
Special Issue Editor
Interests: phytochemicals; food chemistry; lipid metabolism; leukemia; neuroprotection
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Naturally occurring phytochemicals in plants have attracted considerable interest due to their wide-ranging biological activities and therapeutic potential. Growing evidence shows that phytochemicals modulate key molecular signaling pathways involved in inflammation, oxidative stress, apoptosis, cell proliferation, and metabolism. These effects occur through both direct and indirect mechanisms, including the regulation of transcription factors, kinases, and epigenetic modulators. Understanding these interactions is crucial for developing novel preventive and therapeutic strategies for chronic diseases such as cancer, neurodegenerative disorders, cardiovascular diseases, and metabolic syndromes. This Special Issue aims to explore the molecular interaction networks through which phytochemicals exert their biological effects, with a focus on preclinical and clinical studies, novel compounds, and emerging technologies such as omics and systems biology. Submissions addressing structure–activity relationships, synergistic effects, and translational potential are also encouraged. We invite original research articles and comprehensive reviews that advance the current understanding of phytochemical-mediated molecular signaling networks.
Prof. Dr. Jui-Hung Yen
Guest Editor
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Keywords
- phytochemicals
- molecular signaling pathways
- inflammation
- apoptosis
- chronic diseases
- cancer
- cardiovascular diseases
- structure–activity relationships
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