Targeting Oxidative Stress: New Insights into Disease Pathogenesis, Emerging Preventive Strategies and Novel Therapeutic Approaches
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 August 2026 | Viewed by 24
Special Issue Editors
Interests: antioxidants; oxidative stress-related diseases; electronic cigarette toxicity; co-carcinogenesis pathways; DNA repair and mutagenesis; drug metabolism
Special Issues, Collections and Topics in MDPI journals
Interests: oxidative stress status; inflammation; oxidative and post-oxidative markers; antioxidant employment; prevention of chronic diseases; in vitro and in vivo toxicity; biomarkers of exposure; electronic cigarette toxicity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Defined as an imbalance between the production of reactive oxygen, nitrogen or carbon species (ROS/RNS/RCS) and the capacity of antioxidant defence systems, oxidative stress (OS) significantly impacts cellular redox signalling pathways, mitochondrial dysfunction, genomic instability, protein misfolding, inflammation, and tissue damage, playing a key role across various pathological contexts.
The present Special Issue seeks to broaden current understanding of the role of OS in chronic and degenerative diseases, such as cardiovascular and neurodegenerative disorders, metabolic syndromes, cancer, and environmentally driven disorders. The issue also highlights emerging biomarkers, methodological advances for detecting oxidative damage, and the therapeutic potential of antioxidant strategies—from dietary antioxidants to targeted redox-modulating drugs, offering fresh perspectives for early detection, prevention, and innovative therapeutic strategies integrating basic, translational, and clinical perspectives.
This Special Issue will accept original articles, systematic or narrative reviews, with particular emphasis on emerging pharmacological aspects of the modulation of oxidative stress.
Dr. Fabio Vivarelli
Dr. Donatella Canistro
Guest Editors
Manuscript Submission Information
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Keywords
- metabolism
- inflammation
- oxidative stress
- diabetes
- natural oxidative stress modulators
- novel preventive/therapeutic strategies
- ageing
- cardiovascular diseases
- regenerative medicine
- neurodegeneration
- environmental exposure
- cancer
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