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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Insight into Extracellular Vesicles in Proliferative Diseases

edited by Sergio Esquivel-Ruiz

submission deadline 20 Jun 2025 | 2 articles | Viewed by 4351 | Submission Open

Keywords: proliferation; extracellular vesicles; intercellular communication; vesicle cargo; therapeutic applications; biomarkers

(This special issue belongs to the Section Molecular Immunology)

Molecular Pathology Research on Blood Tumors

edited by

Luca Roncati

submission deadline 20 Jun 2025 | 2 articles | Viewed by 4326 | Submission Open

Keywords: molecular pathology; molecular tumor board; blood tumors; leukemia; myeloma; lymphoma; next-generation sequencing; precision oncology; targeted therapy; personalized medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Nuclear Receptors in Diseases

edited by Roberto Palacios-Ramirez

submission deadline 20 Jun 2025 | 2 articles | Viewed by 4245 | Submission Open

Keywords: nuclear receptors; hormone receptors; orphan receptors; retinoid receptors; metabolic diseases; cancers; drug metabolism

(This special issue belongs to the Section Molecular Biology)

Organoids and Organs-on-Chip for Medical Research

edited by

Miguel Hueso

submission deadline 20 Jun 2025 | 3 articles | Viewed by 4113 | Submission Open

Keywords: organoids; organs-on-chip; tissue engineering; disease modeling; biomarkers; molecular pathways; nanotechnology; preclinical models; artificial organs; artificial intelligence; personalized medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Editorial Board Members’ Collection Series: Cardiovascular Diseases

edited by

Melania Gaggini

and

Cristina Vassalle

submission deadline 20 Jun 2025 | 3 articles | Viewed by 4061 | Submission Open

Keywords: cardiovascular disease; metabolism; cardiometabolic risk; coronary artery disease; CVD

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Signalling in Multitrophic Systems Involving Arthropods

edited by

Francesca Barbero

submission deadline 20 Jun 2025 | 4 articles | Viewed by 4029 | Submission Open

Keywords: insects; plants; microorganisms; communication; symbioses; eavesdropping

(This special issue belongs to the Section Molecular Biology)

Cellular and Molecular Targets of Preeclampsia

edited by

Hironori Takahashi

submission deadline 20 Jun 2025 | 2 articles | Viewed by 4029 | Submission Open

Keywords: biomarker; cell biology; remodeling; human placenta; trophoblast; exosome; invasion; preeclampsia; fetal growth restriction

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Latest Review Papers in Macromolecules 2025

edited by

Xiao Hu

Salah-Eddine Stiriba

and

Giuseppe Zanotti

submission deadline 20 Jun 2025 | 2 articles | Viewed by 3967 | Submission Open

Keywords: polymerization; macromolecules modification; composition and topologies of new macromolecular structures; structure– properties relationships; functional macromolecules; micelles; inverse micelles; supramolecular conjugates; order– disorder transition; spectroscopic methods; NMR; macromolecular crystallography; kinetics; thermodynamics; microcalorimetry; fluorescence; single-molecule microscopy; statistical mechanics; computer simulations; computational modeling; molecular modeling; biomacromolecules; sustainable/renewable macromolecules; macromolecular networks; stimulus-responsive macromolecules; nanostructured macromolecules; soft materials; artificial life; drug delivery

(This special issue belongs to the Section Macromolecules)

Molecular Mechanisms of Biological Effects and Transport Processes

edited by

Csaba Hetényi

and Uko Maran

submission deadline 20 Jun 2025 | 2 articles | Viewed by 3950 | Submission Open

Keywords: interaction; enzyme; receptor; ligand; drug; ADMETox; QSAR; permeability; half-life; channel

(This special issue belongs to the Section Molecular Biology)

Harnessing Nature’s Potential: Plant-Derived Substances for Controlling Appetite and Promoting Weight Management

edited by

Gian Carlo Tenore

and Ettore Novellino

submission deadline 20 Jun 2025 | 1 articles | Viewed by 3905 | Submission Open

Keywords: plant-derived substances; obesity; satiety control; weight management; gut hormones; bioactive compounds; energy metabolism; phytochemicals; molecular mechanisms; clinical trials

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Gaucher Disease: From Molecular Mechanisms to Treatments

edited by

Ari Zimran

Shoshana Revel-Vilk

and

Jeff Szer

submission deadline 20 Jun 2025 | 3 articles | Viewed by 3903 | Submission Open

Keywords: Gaucher disease; lysosomal storage disorder (LSD); genetic disorders; animal models; gene therapy approaches

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research Advances in Reproductive Immunology

edited by

Monika Kniotek

submission deadline 20 Jun 2025 | 2 articles | Viewed by 3844 | Submission Open

Keywords: reproductive immunology; immune regulation; fertility; pregnancy; immunocontraception

(This special issue belongs to the Section Molecular Immunology)

Molecular Research Landscape of Pulmonary Arterial Hypertension

edited by Cármen Brás-Silva

submission deadline 20 Jun 2025 | 2 articles | Viewed by 3825 | Submission Open

Keywords: pulmonary arterial hypertension; right ventricle; right heart failure; molecular mechanisms; vascular disease; translational research; therapy

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms for Skin Protection and Aging

edited by Wonchul Lim and

Tae-Gyu Lim

submission deadline 20 Jun 2025 | 3 articles | Viewed by 3824 | Submission Open

Keywords: skin photo-aging; skin inflammation; molecular biology; inner beauty; natural product; skin microbiome; skin wrinkle formation; skin dehydration; skin pigmentation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research on Molecular Dynamics: 2nd Edition

edited by

II Soo Moon

and

Raju Dash

submission deadline 20 Jun 2025 | 2 articles | Viewed by 3706 | Submission Open

Keywords: molecular dynamics; quantum mechanics/molecular mechanics approaches; conformational change; dynamic changes of intermolecular interactions; protein– ligand interactions; nucleic acid ligand interactions; computational modeling of molecular systems; drug design and delivery; structure– function relationships in proteins; simulation of drug-like molecules and lipid membranes

(This special issue belongs to the Section Molecular Biophysics)

Advances in Targeting Macrophages in Immunotherapy

edited by Vinod Nadella

submission deadline 20 Jun 2025 | 1 articles | Viewed by 3704 | Submission Open

Keywords: tumor-associated macrophages; tumor microenvironment; tumor immunology; carcinogenesis; macrophage repolarization; checkpoint inhibitor; immunotherapy; nanomaterials; metabolic reprogramming; epigenetics

(This special issue belongs to the Section Molecular Immunology)

Bioactive Compounds in Microbial Communities and Non-Target Organisms

edited by

María Rosa Pino-Otín

and Elisa Langa

submission deadline 20 Jun 2025 | 2 articles | Viewed by 3697 | Submission Open

Keywords: antimicrobial; environmental microbial communities; ecotoxicity; antibiotic resistance

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Impact of Endogenic and Exogenic Oxidative Stress Triggers on Pregnant Woman, Fetus, and Child, 2nd Edition

edited by

Joško Osredkar

submission deadline 20 Jun 2025 | 1 articles | Viewed by 3651 | Submission Open

Keywords: oxidative stress; angiogenesis; hypertension in pregnancy; preterm birth; metabolic syndrome; biomarkers; toxic agents; follicular fluid; amniotic fluid; cord blood

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Exploring the Genetics and Genomics of Complex Diseases

edited by Keeley Brookes

submission deadline 20 Jun 2025 | 4 articles | Viewed by 3647 | Submission Open

Keywords: complex disease; genetics; polymorphisms; genomics; transcriptome; epigenetics; gene-environment interplay

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Basis of Neuropsychiatric Disorders: Recent and Future Developments

edited by

Konstantinos Tsamakis

submission deadline 20 Jun 2025 | 4 articles | Viewed by 3616 | Submission Open

Keywords: molecular; schizophrenia; depression; genetic; autism; mechanisms; genetic

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Pathogenesis and Therapeutics in Retinopathy

edited by Fabiana Picconi

submission deadline 20 Jun 2025 | 3 articles | Viewed by 3600 | Submission Open

Keywords: retinal neurodegeneration; retinal neurovascular unit; diabetic retinopathy; diabetic neuropathy; diabetic milieu; glucose variability

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Strategies to Improve the Detection of Human Papillomavirus (HPV) Persisting Infections

edited by

Marianna Martinelli

submission deadline 20 Jun 2025 | 3 articles | Viewed by 3580 | Submission Open

Keywords: human papillomavirus; HPV; viral load; genotyping; oncogenic transcripts; biomarkers

(This special issue belongs to the Section Molecular Microbiology)

Vaccine Research and Adjuvant Discovery

edited by

Kendal Ryter

submission deadline 20 Jun 2025 | 2 articles | Viewed by 3572 | Submission Open

Keywords: C-type lectin receptor; mincle; toll-like receptor

(This special issue belongs to the Section Molecular Immunology)

Molecular Biology of Histamine Systems 2024

edited by

Paul L. Chazot

submission deadline 20 Jun 2025 | 1 articles | Viewed by 3564 | Submission Open

Keywords: histamine; molecular biology; genetics; mutations; disease; genomics; histamine signalling; synthesis; metabolism; isoforms; splicing; receptors; gene regulation; molecular structure; microbiome

(This special issue belongs to the Section Molecular Biology)

Solid-Phase Peptides: Syntheses and Applications

edited by

Samir Acherar

submission deadline 20 Jun 2025 | 3 articles | Viewed by 3422 | Submission Open

Keywords: peptide; peptide-based compounds; solid-phase synthesis; molecular interactions; methodology; disease treatments; drug delivery

(This special issue belongs to the Section Molecular Biology)

Molecular Advances and Perspectives in Multiple Sclerosis

edited by Joao Jose Cerqueira and

Fernanda Marques

submission deadline 20 Jun 2025 | 1 articles | Viewed by 3395 | Submission Open

Keywords: astrocytes; axonal transection; demyelination; EBV; immunometabolism; insulin signaling; iron; lymphotoxin; microglia; mitochondria; neurodegeneration; oligodendrocytes; remyelination; brain barriers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Advances in Drug-Induced Neurogenesis

edited by

Tiago Santos

submission deadline 20 Jun 2025 | 2 articles | Viewed by 3359 | Submission Open

Keywords: neurogenesis; neural stem cells; neurogenic niches; subventricular zone; subgranular zone; regeneration; neurodegenerative diseases; drug delivery systems

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Aspects of Hematological Malignancies and Benign Hematological Disorders—3rd Edition

edited by

Amelia Maria Găman

submission deadline 20 Jun 2025 | 3 articles | Viewed by 3327 | Submission Open

Keywords: myeloproliferative neoplasms; leukemia; lymphoma; multiple myeloma; oxidative stress; inflammation; microbiome; genetics; molecular biology

(This special issue belongs to the Section Molecular Biology)

Melanin and Other Pigments: Function, Synthesis and Characterization

edited by Koen P. Vercruysse

submission deadline 20 Jun 2025 | 2 articles | Viewed by 3144 | Submission Open

Keywords: melanin; eumelanin; pheomelanin; allomelanin; catechol; indole; phenol

(This special issue belongs to the Section Biochemistry)

Molecular and Clinical Aspects of Migraine and Its Comorbidities: Epilepsy, Stroke, and Restless Leg Syndrome

edited by

Janusz Blasiak

and Michał Fila

submission deadline 20 Jun 2025 | 1 articles | Viewed by 3133 | Submission Open

Keywords: migraine; genetics and epigenetics of migraine; migraine comorbidities; omics in migraine studies; stem cells in migraine studies; epilepsy; stroke; restless leg syndrome

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Epigenetics in Plant Research

edited by

Hai Du

and

Zhe Liang

submission deadline 20 Jun 2025 | 2 articles | Viewed by 3123 | Submission Open

Keywords: plant; genomics; systematics

(This special issue belongs to the Section Molecular Plant Sciences)

Enhancing Protein Understanding: Exploring Ideal Protein and Absorption Through Molecular Techniques

edited by

Pablo Jesús Marín-García

submission deadline 20 Jun 2025 | 2 articles | Viewed by 3115 | Submission Open

Keywords: ideal protein; amino acid; metabolomics; OMICs; essential; lysine; methionine; threonine; nitrogen; environment

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Ferroptosis: Emerging Mechanisms, Physiological Functions, and Therapeutic Applications

edited by

Shibiao Wan

submission deadline 20 Jun 2025 | 2 articles | Viewed by 3113 | Submission Open

Keywords: ferroptosis; biomarker; iron metabolism; diseases; precision medicine

(This special issue belongs to the Section Biochemistry)

Toxic Liver Injury: Molecular, Mechanistic, and Medical Challenges 3.0

edited by

Rolf Teschke

submission deadline 20 Jun 2025 | 2 articles | Viewed by 3071 | Submission Open

Keywords: liver injury; nonalcoholic fatty liver disease; nonalcoholic steatonecrosis; nonalcoholic liver cirrhosis; hepatocellular carcinoma

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Cellular Intrinsic Modulators in the Pathogenesis of Cancer and Inflammatory Diseases

edited by

Kishu Ranjan

submission deadline 20 Jun 2025 | 1 articles | Viewed by 3047 | Submission Open

Keywords: cancer; immunobiology; chronic diseases; CRISPR; drug discovery; multi-omics

(This special issue belongs to the Section Molecular Oncology)

Chronic Rhinosinusitis: Aetiology, Immunology and Treatment, 3rd Edition

edited by

Seung-Heon Shin

submission deadline 20 Jun 2025 | 1 articles | Viewed by 3044 | Submission Open

Keywords: innate immunity; adaptive immunity; protease; cytokine; inflammation; epithelial cells; fibroblasts; eosinophils; lymphocytes; biologics

(This special issue belongs to the Section Molecular Immunology)

Innovative Therapeutic Approaches in Neuropsychiatric Disorders

edited by Marta Pardo

submission deadline 20 Jun 2025 | 1 articles | Viewed by 3037 | Submission Open

Keywords: neuropsychiatric disorders; pharmacogenomics; pathophysiology; molecular treatment mechanisms; molecular targets for novel drug development; neurotransmitters; synaptic plasticity; epigenetics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cancer Chemoprevention by Natural Products

edited by

Ferenc Budán

submission deadline 20 Jun 2025 | 1 articles | Viewed by 3035 | Submission Open

Keywords: cancer; chemoprevention; phytomedicine; carcinogenesis; gene expression; biomolecules; molecular mechanisms

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Epigenetic Biomarkers—Technologies and Applications in Complex Disease Diagnostics and Beyond

edited by Christa Nöhammer

submission deadline 20 Jun 2025 | 2 articles | Viewed by 2955 | Submission Open

Keywords: epigenetics; DNA/RNA methylation; microRNAs; biomarkers; molecular technologies; tissue; biological fluids

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Precision Medicine: Unraveling Novel Mechanisms and Delivery Strategies in Complex Diseases

edited by

Nuno Vale

submission deadline 20 Jun 2025 | 1 articles | Viewed by 2943 | Submission Open

Keywords: molecular precision therapeutics; disease biomarkers; novel therapeutic molecules; drug delivery strategies; personalized medicine; bioinformatics; nanotechnology; synthetic biology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Zinc Finger Proteins in Biological Processes and Diseases

edited by

Amelia Casamassimi

and Patrizia Gazzerro

submission deadline 20 Jun 2025 | 2 articles | Viewed by 2913 | Submission Open

Keywords: zinc finger domain; CTCF; PRDM family; nuclear receptors; human diseases; transcriptional regulation; epigenetic modifications

(This special issue belongs to the Section Molecular Biophysics)

Biodegradation of Pollutants in the Environment: Omics Approaches 3.0

edited by

Irina Sousa Moreira

submission deadline 20 Jun 2025 | 3 articles | Viewed by 2844 | Submission Open

Keywords: biodegradation; pollutants; genomics; proteomics; metabolomics; metagenomics; transcriptomics; degrading microorganisms; metabolic pathway of degradation

(This special issue belongs to the Section Molecular Toxicology)

Novel Treatment Strategies for Head and Neck Cancer

edited by

Francesca Spirito

submission deadline 20 Jun 2025 | 1 articles | Viewed by 2803 | Submission Open

Keywords: head and neck cancer; drug resistance; cancer initiation; biomarker

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms of Schizophrenia and Novel Treatment Targets

edited by Jenifer Vohs

submission deadline 20 Jun 2025 | 2 articles | Viewed by 2751 | Submission Open

Keywords: schizophrenia and molecular pharmacology; cellular signaling; immunology; metabolism; genomics

(This special issue belongs to the Section Molecular Neurobiology)

Modifications of Molecular Structure and Interactions in Epigenome, 3rd Edition

edited by Uko Maran and

Csaba Hetényi

submission deadline 20 Jun 2025 | 1 articles | Viewed by 2664 | Submission Open

Keywords: molecular epigenetics; chemical epigenetics; cryo-electron microscopy; crystallography; NMR; structural bioinformatics; cheminformatics; molecular modeling; molecular dynamics; docking target selection; target validation; post-translational modification; PTM; covalent modification; methylation; acetylation; histone code; reader; writer; transferase; PHD finger; bromodomain; free energy; binding; isothermal titration calorimetry; surface plasmon resonance spectroscopy; peptide

(This special issue belongs to the Section Molecular Biology)

Advancing Neurological Disorders via Computational Neuroscience and Neural Networks

edited by

Elnaz Pashaei

submission deadline 20 Jun 2025 | 2 articles | Viewed by 2643 | Submission Open

Keywords: neurological disorders; neuroimaging analysis; biomarker identification; computational neuroscience; machine learning; brain aging

(This special issue belongs to the Section Molecular Informatics)

New Insights into the Use of Mouse Models for the Study of Skin Disorders

edited by

Jing Feng

submission deadline 20 Jun 2025 | 2 articles | Viewed by 2638 | Submission Open

Keywords: pain; itch; inflammation; endocrine; infection; hypertrophy; aging; hair loss; wound healing

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Developmental and Reproductive Toxicology

edited by

Hyun-Jung Park

submission deadline 20 Jun 2025 | 1 articles | Viewed by 2604 | Submission Open

Keywords: spermatogenesis; mouse models; reproduction biology; assisted reproductive technology; cell signaling; cellular biology; developmental biology

(This special issue belongs to the Section Molecular Biology)

Effects of Environmental Contaminants on Cell Signaling Pathways

edited by

Brad L. Upham

submission deadline 20 Jun 2025 | 1 articles | Viewed by 2552 | Submission Open

Keywords: cell signaling; environmental contaminants; signal transduction; gap junction; toxic mechanisms

(This special issue belongs to the Section Molecular Biology)

Advanced Electrode and Electrolyte Materials: Molecular Scale Design, Synthesis, Mechanisms and Applications

edited by

Christian Julien

submission deadline 20 Jun 2025 | 3 articles | Viewed by 2484 | Submission Open

Keywords: cathode; anode; electrolyte; synthesis; electrochemistry; rechargeable batteries; lithium-ion batteries; all-solid-state lithium metal batteries

(This special issue belongs to the Section Materials Science)

Displaying special issue 651-700 on page 14 of 68.

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