Novel Treatment Strategies for Head and Neck Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 20 June 2025 | Viewed by 3128
Special Issue Editor
Interests: oral carcinoma; cancer stem cells; odontogenic tumours; oral mucositis; targeted therapies; oral potentially malignant disorders; microRNAs; long non-coding RNAs.
Special Issue Information
Dear Colleagues,
Despite advances in medical imaging and therapeutic approaches, the prognosis for patients with advanced head and neck cancer remains poor, with a 5-year survival rate still below 50%. Therefore, there is an urgent need for new treatment strategies to improve patient outcomes. The lack of substantial improvement in overall survival over the past three decades is largely due to the resistance of cancer cells to conventional radiotherapy and chemotherapy. To develop more effective therapeutic strategies, it is crucial to gain a deeper understanding of the molecular and cellular mechanisms underlying cancer initiation, progression, and recurrence.
This Special Issue focuses on new treatment strategies for head and neck cancer, aiming to enhance our molecular knowledge of these tumors to inform better therapies. We invite researchers to submit their original research articles and reviews that address innovative therapeutic approaches and treatment modalities for head and neck cancer. Topics of interest include, but are not limited to, targeted therapies, immunotherapies, combination treatments, personalized medicine, and advances in radiotherapy and chemotherapy. We also welcome studies on biomarkers for therapy response, drug resistance mechanisms, and clinical trials. Submissions may include experimental studies using in vitro and in vivo models, including patient-derived xenograft animal models, as well as biomarker analyses of patient saliva or other body fluids and research on tumor-derived microRNA or extracellular vesicles. Review articles that provide comprehensive overviews of current treatment strategies and future directions in the therapy of head and neck cancer are also encouraged.
Dr. Francesca Spirito
Guest Editor
Manuscript Submission Information
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Keywords
- head and neck cancer
- drug resistance
- cancer initiation
- biomarker
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