Ferroptosis: Emerging Mechanisms, Physiological Functions, and Therapeutic Applications
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: 30 August 2024 | Viewed by 69
Special Issue Editor
Interests: bioinformatics; machine learning; computational biology; single cell analysis; genomics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Ferroptosis is a form of programmed cell death that is triggered by the accumulation of intracellular lipid peroxidation and is dependent on iron. Recent studies have shown that ferroptosis plays a crucial role in regulating cell oxidative stress, metabolism, and immune response, and is involved in various physiological and pathological processes in the body. It is now understood that ferroptosis can inhibit tumor growth and enhance the effectiveness of chemotherapy and immunotherapy in treating cancer. However, ferroptosis can also lead to damage in normal tissues and organs, contributing to the development of diseases such as cardiovascular and neurodegenerative disorders. By targeting ferroptosis and understanding its role in disease progression, researchers can develop new strategies for treatment and potentially improve human health outcomes.
In this Special Issue, we invite submissions of perspective, original article, review, commentary, or letter type of manuscripts that delve into topics such as, but not limited to, the following:
- ferroptosis and disease occurrence and/or development;
- ferroptosis biomarkers for lipid and/or iron metabolism in the onset and progression of diseases;
- Gene regulation of ferroptosis in diseases;
- Development and application of ferroptosis inhibitors and agonists (including nanomaterials);
- Application of ferroptosis in precision medicine and clinical transformation.
Dr. Shibiao Wan
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- ferroptosis
- biomarker
- iron metabolism
- diseases
- precision medicine
