Gamete Development, Differentiation, and Toxicity

Dear Colleagues,

The study of gamete development, differentiation, and toxicity plays a pivotal role in reproductive biology and environmental health. Gamete development, encompassing spermatogenesis and oogenesis, involves intricate cellular processes that are critical for fertility. Understanding the molecular mechanisms guiding these processes is essential for addressing reproductive disorders and improving assisted reproductive technologies. The differentiation of reproductive organs is another crucial facet, exploring the genetic and epigenetic factors shaping male and female reproductive systems. Simultaneously, research in reproductive toxicity investigates the impact of environmental pollutants, chemicals, and endocrine disruptors on gamete health and embryonic development. This interdisciplinary field bridges reproductive biology and toxicology, shedding light on the potential hazards that substances pose to fertility. The igained from this research not only inform clinical practices for treating infertility but also contribute to regulatory measures promoting environmental sustainability and reproductive health awareness. Overall, this research is instrumental in safeguarding reproductive well-being and understanding the intricate processes governing life's initiation.

We are sure that this collection will be a useful guide for scientists and clinicians. Data on molecular mechanisms or pathophysiology are essential, and papers that only contain clinical trials/data are not within the scope of this Special Issue.

Dr. Hyun-Jung Park
Guest Editor

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• spermatogenesis
• mouse models
• reproduction biology
• assisted reproductive technology
• cell signaling
• cellular biology
• developmental biology