International Journal of Molecular Sciences

Valorization of Agri-Food Wastes: Extraction, Characterization and Functional Applications of Bioactive Compounds

edited by Pittaya Chaikham

submission deadline 30 Sep 2026 | Viewed by 492 | Submission Open

Keywords: agri-food waste valorization; bioactive compounds; functional foods; green extraction; food sustainability; plant-based ingredients; antioxidants; circular economy; probiotics; food processing

(This special issue belongs to the Section Biochemistry)

Cellular Pathways and Cytokine Networks in Tuberous Sclerosis: Mechanisms and Therapeutic Targets

edited by Uchenna John Unachukwu

submission deadline 30 Sep 2026 | Viewed by 492 | Submission Open

Keywords: mTOR signaling dysregulation; neurocristopathy; cytokine crosstalk; TSC1/TSC2 complex; epigenetic modifiers; metabolic reprogramming; molecular biomarkers; spatial transcriptomics

(This special issue belongs to the Section Molecular Biology)

Emerging Cardiovascular Drugs and Nutraceuticals: Mechanistic Insights, Translational Research and Clinical Impacts

edited by Pietro Mazzeo,

Vincenzo Vestuto

and Elena Mele

submission deadline 30 Sep 2026 | Viewed by 491 | Submission Open

Keywords: cardiovascular disease; drug mechanisms; nutraceuticals; precision medicine; multi-omics approaches

(This special issue belongs to the Section Molecular Pharmacology)

Transformation and Associated Isotope Kinetics of Halogenated Organic Pollutants in the Environment and Living Organisms

edited by Chenchen Huang

submission deadline 30 Sep 2026 | 1 articles | Viewed by 487 | Submission Open

Keywords: halogenated organic pollutants; compound-specific isotope analysis; isotope fractionation; source apportionment; transformation discrimination; mechanism elucidation; biotic and abiotic transformation; transformation kinetics and pathways; environmental fate

(This special issue belongs to the Section Biochemistry)

Cellular and Molecular Mechanisms of Biological Interactions with Carbon-Based Materials

edited by Ângela Almeida and

Francesca Coppola

submission deadline 30 Sep 2026 | 1 articles | Viewed by 484 | Submission Open

Keywords: carbon (nano)materials; (nano)toxicology; biomaterial interactions; biosensors; remediation; risk assessment

(This special issue belongs to the Section Molecular Nanoscience)

Omega-6 and Omega-3 Fatty Acid Imbalance: Roles in Human Health and Pathogenesis of Diseases

edited by

Jing X. Kang

submission deadline 30 Sep 2026 | Viewed by 482 | Submission Open

Keywords: omega-6/omega-3 ratio; omega-6 fatty acids; omega-3 fatty acids; omega-6/omega-3 imbalance; lipid metabolism; inflammation; chronic diseases; cardiovascular disease; cancer; metabolic syndrome; neurodegenerative diseases; autoimmune diseases; nutritional interventions; polyunsaturated fatty acids (PUFAs); molecular mechanisms; disease pathogenesis; disease management; health promotion

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Recent Advances in Electrochemical-Related Materials: 2nd Edition

edited by Celia García-Hernandez

submission deadline 30 Sep 2026 | 1 articles | Viewed by 470 | Submission Open

Keywords: novel electrochemical devices; advanced micro- and nanomaterials for electrochemical applications; batteries; fuel and photoelectrochemical cells; electrochemical sensors and biosensors; new advances in supercapacitors; electrochemical electrolyzers; advanced electrochemical materials for environmental applications

(This special issue belongs to the Section Materials Science)

Next-Generation Sequencing in Cancer: Genomics, Diagnostics and Therapeutics

edited by Adam Szpechciński and Magdalena Pelc

submission deadline 30 Sep 2026 | 1 articles | Viewed by 465 | Submission Open

Keywords: next-generation sequencing (massively parallel sequencing); whole-genome sequencing (WGS); whole-exome sequencing (WES); RNA sequencing (RNA-seq); single-cell sequencing (SCS); germline and somatic mutations; gene rearrangements (fusions); epigenetics; molecular diagnostics; bioinformatics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Pathogenic Escherichia coli: Cellular Biology, Mechanisms of Pathogenesis, Therapeutic Approaches and Strategies for Disease Intervention

edited by

Jorge Goldstein

submission deadline 30 Sep 2026 | Viewed by 454 | Submission Open

Keywords: enterohemorrhagic E. coli; EHEC; Shiga toxin-producing E. coli; STEC; HUS; inflammation; kidney; blood; brain; pathogenesis; antibodies; extraintestinal pathogenic E. coli; E. coli pathotypes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research on Immune Mechanisms in Kidney Disease

edited by Niels Olsen Saraiva Câmara

submission deadline 30 Sep 2026 | Viewed by 447 | Submission Open

Keywords: kidney disease; molecular sensors; kidney metabolism; immunity; AKI to CKD transition

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Patient-Derived iPSC Models in Chronic Disease Research

edited by

Valentina Parra

submission deadline 30 Sep 2026 | Viewed by 443 | Submission Open

Keywords: induced pluripotent stem cells; patient-derived iPSCs; chronic diseases; disease modeling; molecular mechanisms; stem cell differentiation; gene editing; organoids; personalized medicine; multi-omics

(This special issue belongs to the Section Molecular Biology)

Novel Molecular Pathways and Therapeutic Strategies in Atherosclerotic Cardiovascular Disease

edited by

Elisabeta Badila

and Catalin Adrian Buzea

submission deadline 30 Sep 2026 | Viewed by 433 | Submission Open

Keywords: atherogenesis; vascular inflammation; immune modulation; lipid metabolism; clonal hematopoiesis (CHIP); endothelial dysfunction; plaque instability; epigenetic regulation; molecular signaling pathways; precision cardiovascular medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pharmacological Agents for Soft Tissue and Articular Injections: From Mechanisms to Clinical Applications

edited by

Carmelo Pirri

submission deadline 30 Sep 2026 | Viewed by 433 | Submission Open

Keywords: injectable pharmacological agents; musculoskeletal disorders; injection therapies; platelet-rich plasma (PRP); hyaluronic acid

(This special issue belongs to the Section Molecular Pharmacology)

Advances in Molecular Plant Physiology and Genomic Breeding of Cereals

edited by

Abdullah Shalmani

submission deadline 30 Sep 2026 | Viewed by 423 | Submission Open

Keywords: cereals; molecular physiology; genomic breeding; stress tolerance; functional genomics; genome editing; QTL mapping; multiomics; genotype–environment interactions

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms of Gut Microbiota-Mediated Drug Efficacy and Toxicity

edited by

Jin-Yi Wan

submission deadline 30 Sep 2026 | Viewed by 417 | Submission Open

Keywords: gut microbiota; pharmacomicrobiomics; drug metabolism; drug toxicity; drug efficacy; xenobiotic biotransformation; precision medicine; cancer immunotherapy; fecal microbiota transplantation; host–microbiome interactions

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Metabolomics in Cancer: From Biomarkers to Therapeutic Insights

edited by Filipa Amaro,

Paula Guedes de Pinho

and

Joana Pinto

submission deadline 30 Sep 2026 | Viewed by 410 | Submission Open

Keywords: cancer metabolomics; metabolic reprogramming; biomarker discovery; precision oncology; machine learning; clinical data integration; translational cancer research

(This special issue belongs to the Section Molecular Oncology)

Genome-Wide Association Studies of Complex Diseases and Related Endophenotypes and Biomarkers

edited by M. Ilyas Kamboh

submission deadline 30 Sep 2026 | Viewed by 403 | Submission Open

Keywords: genome-wide association studies; complex diseases; endophenotypes; biomarkers; rare variants; copy number variants; diverse populations

(This special issue belongs to the Section Molecular Genetics and Genomics)

Inflammatory Bowel Disease and Cardiometabolic Comorbidities: Molecular Mechanisms and Therapeutic Perspectives

edited by

Dimitrios Patoulias

and

Christos Mademlis

submission deadline 30 Sep 2026 | Viewed by 399 | Submission Open

Keywords: cardiovascular–kidney–metabolic syndrome; diabetes; obesity; cardiovascular disease; inflammatory bowel disease; Crohn’s disease; ulcerative colitis; inflammation; endothelial dysfunction

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Integrating Multi-Omics Approaches in Fish Immunology to Improve Aquaculture Sustainability

edited by

Parasuraman Aiya Subramani

submission deadline 30 Sep 2026 | Viewed by 397 | Submission Open

Keywords: machine learning; network analysis; vaccine development; genomic selection; single-cell RNA-seq; meta-analysis; innate immunity; biomarker discovery

(This special issue belongs to the Section Molecular Immunology)

Novel Insights into Endothelial Cell Biology

edited by

Takato Hara

and

Toshiyuki Kaji

submission deadline 30 Sep 2026 | Viewed by 379 | Submission Open

Keywords: endothelial cell heterogeneity; mechanotransduction; endothelial–immune interactions; endothelial senescence; vascular barrier regulation; extracellular vesicles; angiogenesis and vascular remodeling; endothelial metabolism; endothelial regulation of the fibrinolytic system

(This special issue belongs to the Section Molecular Biology)

Genetic Diversity, Founder Effects, and Migration in Neurodegeneration: Molecular and Population Perspectives

edited by

Dasiel Oscar Borroto-Escuela

submission deadline 30 Sep 2026 | Viewed by 378 | Submission Open

Keywords: neurodegeneration; population genetics; founder effects; genetic diversity; migration and disease risk; spinocerebellar ataxia; Alzheimer’s disease; Parkinson’s disease; genetic epidemiology; underrepresented populations

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Interplay: Natural Antioxidants as Modulators of Redox Homeostasis

edited by

Giovanni Pratelli

and

Daniela Carlisi

submission deadline 30 Sep 2026 | Viewed by 377 | Submission Open

Keywords: natural antioxidants; oxidative stress; chronic diseases; molecular mechanisms; cancer; neurodegenerative diseases; metabolic disorders; redox biology; omics; precision medicine

(This special issue belongs to the Section Molecular Biology)

Advances in Therapeutic Antibody Engineering

edited by

Chatchai Tayapiwatana

submission deadline 30 Sep 2026 | Viewed by 372 | Submission Open

Keywords: therapeutic antibodies; bispecific antibodies; antibody-drug conjugates (ADCs); nanobodies; AI-driven drug design; Fc engineering; immunotherapy

(This special issue belongs to the Section Molecular Immunology)

Molecular Determinants of Cardiovascular Diseases

edited by

Susan Darroudi

submission deadline 30 Sep 2026 | Viewed by 368 | Submission Open

Keywords: atherosclerosis; hypertension; diabetes; dyslipidemia; endothelial dysfunction; vascular remodeling; inflammation and oxidative stress; mitochondrial dysfunction; molecular diagnostics; heart function

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Pituitary Neuroendocrine Tumors: From Growth Control to Plasticity and Evolutionary Pathogenesis

edited by Ana Lucía De Paul and Liliana del Valle Sosa

submission deadline 30 Sep 2026 | Viewed by 358 | Submission Open

Keywords: tumor heterogeneity; tumor biomarkers; transcriptomics; molecular neuroscience; clinical treatment; pathogenesis; pituitary neuroendocrine tumors; neuroendocrine tumors; nonfunctional; PIT1; pituitary adenoma

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Role of Bifunctional Antibodies in Human Cancer

edited by

Alessandro Canella

submission deadline 30 Sep 2026 | Viewed by 355 | Submission Open

Keywords: bispecific antibodies; tumor immune microenvironment (TIME); cancer immunotherapy; tumor associated antigens; biomarker discovery; T cell engagers (BiTEs, TriTEs, TriKEs); dual affinity retargeting antibodies (DARTs); Fc engineering and FcγR modulation; tumor associated antigen (TAA) avidity optimization; immune reprogramming; bispecific antibody pharmacokinetics and biodistribution; antibody–drug conjugate (ADC) hybrid formats; bifunctional antibodies

(This special issue belongs to the Section Molecular Oncology)

Molecular Studies of Cartilage Deformation

edited by

Kazuo Yudoh

submission deadline 30 Sep 2026 | Viewed by 355 | Submission Open

Keywords: osteoarthritis; chondrocyte; mitochondria function; mechanical stress; oxidative stress; cartilage metabolism

(This special issue belongs to the Section Molecular Biology)

Current Trends in Nanophotonics and Molecular-Scale Light Control

edited by Mitradeep Sarkar

submission deadline 30 Sep 2026 | Viewed by 343 | Submission Open

Keywords: nanophotonics; light–matter interaction; metamaterials and 2D materials; photonic crystals; molecular sensing and imaging; quantum and nonlinear optics

(This special issue belongs to the Section Molecular Nanoscience)

Procoagulant Platelets in Vascular Disease and Beyond

edited by

Paresh P. Kulkarni

submission deadline 30 Sep 2026 | Viewed by 337 | Submission Open

Keywords: procoagulant platelets; thrombosis; hemostasis; coagulation; bleeding; vascular disease; cancer; cardiometabolic syndrome; inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Future Perspective and Challenge of Nanomaterials

edited by

Antreas Afantitis

submission deadline 30 Sep 2026 | Viewed by 334 | Submission Open

Keywords: nanomaterial; nanoinformatics; materials informatics; functional material; molecular dynamics

(This special issue belongs to the Section Molecular Nanoscience)

MicroRNAs in Cancer: Molecular Mechanisms and Regulatory Networks

edited by

Yarely M. Salinas-Vera

submission deadline 30 Sep 2026 | Viewed by 328 | Submission Open

Keywords: microRNAs; cancer; non-coding RNAs; gene regulation; tumor microenvironment; transcriptomics; cancer signaling

(This special issue belongs to the Section Molecular Biology)

Regulatory T Cells and Immune Tolerance: From Nobel Discoveries to Clinical Breakthroughs

edited by Raquel López-Mejías

submission deadline 30 Sep 2026 | Viewed by 327 | Submission Open

Keywords: regulatory T cells (Tregs); immune tolerance; FOXP3 gene; therapies; immunotherapy

(This special issue belongs to the Section Molecular Immunology)

Inherited Endocrine Tumors: Genetics, Genomics, and Molecular Pathogenesis

edited by Vito Guarnieri,

Alberto Falchetti

and Antonio Stefano Salcuni

submission deadline 30 Sep 2026 | Viewed by 326 | Submission Open

Keywords: parathyroid; adrenal; pancreas; thyroid; pituitary

(This special issue belongs to the Section Molecular Genetics and Genomics)

Effects of Radiation on Biomolecules and Cells: Mechanisms, Responses, and Biological Implications

edited by

Sachin Gulati

submission deadline 30 Sep 2026 | Viewed by 325 | Submission Open

Keywords: radiation biology; biomolecular damage; cellular responses; DNA damage and repair; oxidative stress; radioprotection; radiotherapy; dosimetry; molecular mechanisms; radiation-induced toxicity

(This special issue belongs to the Section Molecular Biology)

Pathophysiology of Preeclampsia and Gestational Diabetes: Shared Molecular Mechanisms in Pregnancy-Related Disorders

edited by Tamara Nikolic Turnic

submission deadline 30 Sep 2026 | Viewed by 322 | Submission Open

Keywords: preeclampsia; molecular mechanism; mechanism of preventive/curative strategies; placenta dysfunction

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Biological Effects and Toxicity of Nanomaterials

edited by Lucyna Kapka-Skrzypczak

submission deadline 30 Sep 2026 | Viewed by 321 | Submission Open

Keywords: nanotoxicology; nanomaterials; biological effects; cytotoxicity; oxidative stress; inflammation; genotoxicity; immunotoxicity; risk assessment; nanosafety; nanomedicine; environmental health; in vitro models; in vivo studies

(This special issue belongs to the Section Molecular Nanoscience)

TRIM Family Proteins and Beyond: Molecular Mechanisms in Tissue Homeostasis and Disease

edited by

Chuanxi Cai

submission deadline 30 Sep 2026 | Viewed by 317 | Submission Open

Keywords: TRIM family proteins; E3 ubiquitin ligases; protein homeostasis; autophagy and selective autophagy; innate immunity and antiviral defense; signal transduction; post-translational modifications; phase separation; tissue homeostasis; cancer biology; heart failure; neurodegeneration; inflammation and immunity; molecular mechanisms of disease; biomarkers and therapeutic targets

(This special issue belongs to the Section Molecular Biology)

Targeted Therapies and Chemoresistance in Gastrointestinal Cancers

edited by Zheng Chen

submission deadline 30 Sep 2026 | Viewed by 309 | Submission Open

Keywords: gastrointestinal cancer; targeted therapy; chemoresistance; drug resistance; precision medicine; molecular biomarkers; signal transduction; tumor microenvironment; immunotherapy; novel therapeutics

(This special issue belongs to the Section Molecular Oncology)

Advances in Cell Signaling Pathways and Signal Transduction, 2nd Edition

edited by

Susumu Ohya

and Katsuhiko Muraki

submission deadline 30 Sep 2026 | Viewed by 308 | Submission Open

Keywords: signaling pathway; signal transduction; cell biology; signal transduction; cell communication; cell signaling

(This special issue belongs to the Section Biochemistry)

Deep Learning for Bioinformatics and Biomedicine

edited by

Burak Tasci

submission deadline 30 Sep 2026 | Viewed by 305 | Submission Open

Keywords: bioinformatics; deep learning; genomics (DNA); histopathology; multi-omics; molecular biomarkers; drug discovery; computational pathology; systems biology; precision medicine

(This special issue belongs to the Section Molecular Informatics)

Molecular Immunity to Parasitic Infections

edited by Jamie A. Whitelaw and Stuart Woods

submission deadline 30 Sep 2026 | Viewed by 302 | Submission Open

Keywords: parasitology; immunology; vaccines; cell therapy; gene editing; parasitic diseases; immune responses; inflammation; molecular mechanisms; immune evasion; host cell invasion and manipulation

(This special issue belongs to the Section Molecular Immunology)

Molecular Genetics in Metabolic Syndrome and Diabetes

edited by

Marijn Speeckaert

submission deadline 30 Sep 2026 | Viewed by 296 | Submission Open

Keywords: metabolic syndrome; diabetes mellitus; genetic variants; epigenetics; insulin resistance; obesity; dyslipidemia; inflammation; oxidative stress; mitochondrial dysfunction; non-coding RNAs; transcriptomics; proteomics

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

State-of-the-Art Molecular Plant Sciences in Thailand

edited by

Mayura Veerana

submission deadline 30 Sep 2026 | Viewed by 293 | Submission Open

Keywords: molecular plant sciences; plant biotechnology; functional genomics; molecular breeding; plant stress responses; omics technologies; plant–microbe interactions; sustainable agriculture; crop improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Targeting in Neuroinflammation: Uncovering Mechanisms, Pharmacological Targets and Neuropharmaceutical Developments

edited by

Nataša Mitrović

submission deadline 30 Sep 2026 | Viewed by 282 | Submission Open

Keywords: neuroinflammation; neurodegenerative disorders; neuro-immune crosstalk; glial cells; neuroprotective/anti-inflammatory agents; therapeutic strategies; pharmacological treatments

(This special issue belongs to the Section Molecular Neurobiology)

Multiscale Toxicology: From Cell Models to Whole Organisms

edited by

Elvira Brunelli

and

Rachele Macirella

submission deadline 30 Sep 2026 | Viewed by 277 | Submission Open

Keywords: toxicology; ecotoxicology; environmental risk assessment; multiscale toxicology; emerging contaminants; sentinel species; omics; mixture toxicity

(This special issue belongs to the Section Molecular Toxicology)

Molecular Mechanisms Underlying Genetic Variants of Parkinson’s Disease

edited by Michael Schlossmacher and

Ari Zimran

submission deadline 30 Sep 2026 | Viewed by 274 | Submission Open

Keywords: DNA; PD prevention; genetic variants of Parkinson's disease

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanisms of Endocrine-Disrupting Chemicals in Reproductive Toxicity

edited by

Dragana Samardžija Nenadov

submission deadline 30 Sep 2026 | 1 articles | Viewed by 274 | Submission Open

Keywords: endocrine-disrupting chemicals (EDCs); reproductive toxicity; steroidogenesis; molecular mechanisms; intracellular signaling; hormone receptors; reproductive health

(This special issue belongs to the Section Molecular Toxicology)

Enhancing Plant Traits Through In Vitro Culture

edited by Jacek Gawroński

submission deadline 30 Sep 2026 | Viewed by 274 | Submission Open

Keywords: plant tissue culture; somatic embryogenesis; organogenesis; micropropagation; callus culture; in vitro regeneration; in vitro mutagenesis; haploid and doubled haploid production; molecular markers; genetic analysis; genomics; transcriptomics; epigenetic regulation; proteomic profiling; molecular mechanisms; gene expression analysis

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Insights into Animal Nutrition: Oxidative Stress, Polyphenols and Functional Feed Materials

edited by

Sotiria Makri

and

Dimitrios Kouretas

submission deadline 30 Sep 2026 | Viewed by 271 | Submission Open

Keywords: animal nutrition; oxidative stress; reactive oxygen species; polyphenols; feed materials; molecular nutrition; antioxidant defense; animal physiology; nutritional toxicology

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Interactions Between Rhizosphere Microbiota and Plants

edited by

Anna Gałązka

submission deadline 30 Sep 2026 | Viewed by 271 | Submission Open

Keywords: microbiome and mycobiome of soil and plant rhizosphere; endorhizosphere; next-generation sequencing; soil and plant biodiversity

(This special issue belongs to the Section Molecular Plant Sciences)

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