Molecular Genetics in Metabolic Syndrome and Diabetes
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".
Deadline for manuscript submissions: 30 September 2026 | Viewed by 116
Special Issue Editor
Interests: biochemistry; biomarkers; hypertension; cardiovascular disease; kidney disease, diabetes
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Metabolic syndrome and diabetes are complex, multifactorial disorders that represent a major and growing global health burden. Their pathogenesis involves intricate interactions between genetic predisposition and environmental and lifestyle factors, leading to disturbances in glucose and lipid metabolism, insulin resistance, chronic low-grade inflammation, and vascular dysfunction. Recent advances in molecular genetics and high-throughput technologies have provided unprecedented insights into the biological mechanisms underlying these metabolic disorders. This Special Issue of the International Journal of Molecular Sciences, entitled “Molecular Genetics in Metabolic Syndrome and Diabetes”, aims to present current advances in the identification and functional characterization of genetic and molecular determinants involved in the onset, progression, and complications of metabolic syndrome and diabetes. We welcome original research articles and state-of-the-art reviews addressing genetic variants, epigenetic modifications, transcriptomic and proteomic alterations, non-coding RNAs, mitochondrial dysfunction, inflammation, oxidative stress, and gene–environment interactions relevant to metabolic dysregulation. Studies exploring molecular mechanisms underlying disease heterogeneity, cardiometabolic risk, and therapeutic response are particularly encouraged. By integrating data from basic, translational, and clinical research, this Special Issue seeks to enhance our molecular understanding of metabolic syndrome and diabetes and to support the development of novel biomarkers and precision medicine strategies for improved prevention, diagnosis, and treatment.
Prof. Dr. Marijn Speeckaert
Guest Editor
Manuscript Submission Information
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Keywords
- metabolic syndrome
- diabetes mellitus
- genetic variants
- epigenetics
- insulin resistance
- obesity
- dyslipidemia
- inflammation
- oxidative stress
- mitochondrial dysfunction
- non-coding RNAs
- transcriptomics
- proteomics
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