Novel Insights into Endothelial Cell Biology
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 September 2026 | Viewed by 171
Special Issue Editors
Interests: vascular endothelial cells; vascular smooth muscle cells; atherosclerosis; bioorganometallics; proteoglycans
Interests: signaling and cell response; transporter; vascular toxicity; extracellular matrix; atherosclerosis; blood coagulation-fibrinolytic system; growth factors; cytokines
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Endothelial cells line the entire vascular system and play essential roles beyond their classical barrier and transport functions. Recent technological advances including single-cell transcriptomics, organ-on-chip platforms and high-resolution imaging have uncovered a previously unrecognized complexities in endothelial cell heterogeneity, mechano-transduction, immunomodulatory capacity and disease-associated phenotypes.
These discoveries have expanded our understanding of vascular biology and highlighted endothelial cells as key regulators of both physiological homeostasis and a wide spectrum of pathological processes such as inflammation, atherosclerosis, cancer progression and aging.
This Special Issue aims to present recent advances and emerging perspectives in this evolving field.
In this Special Issue, both original research articles and reviews are welcome.
Research areas may include (but are not limited to) the following:
- Endothelial cell heterogeneity and plasticity
- Mechanotransduction and endothelial responses to shear stress
- Endothelial–immune interactions and their roles in inflammation
- Endothelial senescence and aging-related vascular dysfunction
- Regulation of endothelial barrier integrity and vascular permeability
- Extracellular vesicles in endothelial communication and disease
- Angiogenesis, vascular remodeling and regenerative approaches
- Novel-imaging, organoid or microfluidic models for studying endothelial biology
Dr. Takato Hara
Prof. Dr. Toshiyuki Kaji
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- endothelial cell heterogeneity
- mechanotransduction
- endothelial–immune interactions
- endothelial senescence
- vascular barrier regulation
- extracellular vesicles
- angiogenesis and vascular remodeling
- endothelial metabolism
- endothelial regulation of the fibrinolytic system
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
