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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Plant Resilience: Insights into Abiotic and Biotic Stress Adaptations

edited by

Xujun Zhu

submission deadline 20 Oct 2025 | 5 articles | Viewed by 4856 | Submission Open

Keywords: plants; basis of life; environmental stress; complex responses; molecular mechanisms; abiotic and biotic stress adaptations

(This special issue belongs to the Section Molecular Plant Sciences)

Pathophysiology and Pharmacology in Psychiatry

edited by

Galila Agam

submission deadline 20 Oct 2025 | 2 articles | Viewed by 4822 | Submission Open

Keywords: psychiatric disorders; mental health; pathophysiology; neuropsychopharmacology; brain

(This special issue belongs to the Section Molecular Neurobiology)

Zebrafish as a Model for Biomedical Studies—2nd Edition

edited by

Pierre-Olivier Angrand

submission deadline 20 Oct 2025 | 3 articles | Viewed by 4707 | Submission Open

Keywords: zebrafish; cancer; metabolic diseases; neurological disorders; infectious diseases; xenografts; drug discovery

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanism in Cardiovascular Pathology

edited by Andrea Marzullo

submission deadline 20 Oct 2025 | 3 articles | Viewed by 4618 | Submission Open

Keywords: cardiovascular diseases; molecular biology; sudden death; cardiomyopathies; heart failure; coronary artery diseases; pericarditis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Research on Novel Lipid-Based Nano Drug Delivery Systems

edited by

Eder Lilia Romero

submission deadline 20 Oct 2025 | 1 articles | Viewed by 4562 | Submission Open

Keywords: lipids; nanoparticle; nanovesicle; algae; archaea; plant; bacteria; natural product

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Aspects of Cartilage Biology

edited by

Michela Geminiani

submission deadline 20 Oct 2025 | 3 articles | Viewed by 4447 | Submission Open

Keywords: cartilage biology; tissue regeneration; molecular mechanisms; chondrocytes; cartilage disorders; therapeutic interventions; biomaterials

(This special issue belongs to the Section Molecular Biology)

Applications of Bacteriophages

edited by

Grzegorz Wegrzyn

submission deadline 20 Oct 2025 | 1 articles | Viewed by 4406 | Submission Open

Keywords: bacteriophages; gene cloning; phage display technology; phage

(This special issue belongs to the Section Molecular Biology)

Small Cell Lung Cancer Entering the Sphere of Personalized Treatment

edited by

Anna Grenda

, Michał Szczyrek and Izabela Chmielewska

submission deadline 20 Oct 2025 | 2 articles | Viewed by 4401 | Submission Open

Keywords: small cell lung cancer; SCLC; pathological subtypes; molecular subtypes; DNA; RNA; NGS; next-generation sequencing transcriptome; mutations; molecular analysis

(This special issue belongs to the Section Molecular Oncology)

Hormone/Receptor System in Human Diseases

edited by

Elena Zocchi

submission deadline 20 Oct 2025 | 2 articles | Viewed by 4356 | Submission Open

Keywords: characteristics of hormones; mechanisms of hormone action; structure; subunits and complexes of receptors; receptor function; expression and regulation; hormone/receptor signaling; interactions between receptors and hormones

(This special issue belongs to the Section Molecular Pharmacology)

Gynecologic Oncology: Molecular Mechanisms and Therapies

edited by

Angel Yordanov

submission deadline 20 Oct 2025 | 3 articles | Viewed by 4340 | Submission Open

Keywords: cervical cancer; endometrial cancer; ovarian cancer; vulvar cancer; carcinogenesis; microinvairment; immunotherapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research in Rheumatoid Arthritis

edited by Ângelo Calado

submission deadline 20 Oct 2025 | 2 articles | Viewed by 4325 | Submission Open

Keywords: rheumatoid arthritis; synovium; autoimmunity; rheumatology; omics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bioprinting: Progress and Challenges

edited by

Rui Vitorino

submission deadline 20 Oct 2025 | 1 articles | Viewed by 4322 | Submission Open

Keywords: advances in 3D bioprinting technologies; biomaterials for bioprinting; bioprinting applications in tissue engineering and regenerative medicine; cellular and molecular interactions in bioprinted constructs; bio-printed organ and tissue models for disease research

(This special issue belongs to the Section Materials Science)

DNA Damage in Neurological Disorders: Etiological and Therapeutical Aspects

edited by Tam Quach, Ilaria Palmisano and Anne-Marie Duchemin

submission deadline 20 Oct 2025 | 1 articles | Viewed by 4249 | Submission Open

Keywords: neurological disorders; peripheral neuropathies; DNA damage; epigenetic dynamism; 3D chromatin organization/remodeling; therapeutic targets for DNA repair

(This special issue belongs to the Section Molecular Neurobiology)

Protein Biosensors

edited by

Antonio Varriale

and

Maria Staiano

submission deadline 20 Oct 2025 | 2 articles | Viewed by 4212 | Submission Open

(This special issue belongs to the Section Biochemistry)

Recent Advances in Photocatalysis: An Innovation in Catalysis

edited by

Andreea L. Chibac-Scutaru

submission deadline 20 Oct 2025 | 2 articles | Viewed by 4141 | Submission Open

Keywords: semiconducting nanostructures; photocatalyst immobilized on substrates; hybrid composites; metal-free photocatalyst; photocatalysis mechanism; pollutant removal; hydrogen production; organic synthesis

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Metabolic Diseases and Genetic Variants

edited by Rajkumar Dorajoo

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3979 | Submission Open

Keywords: genetic variants; DNA sequencing; metabolic disease; whole exome sequencing; quantitative trait loci; fine-mapping; epidemiology; omics; T2D; obesity

(This special issue belongs to the Section Molecular Genetics and Genomics)

Paradox of Salmonella Survival and Host Defense Strategies

edited by

John Hwa Lee

and Amal Senevirathne

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3883 | Submission Open

Keywords: Salmonella; Salmonella serovars; virulence factors; host immune response; human health; animal health and poductivity; infection models

(This special issue belongs to the Section Molecular Microbiology)

Cutting-Edge Methods for Exploiting Bioactive Compounds in Biomasses: From the Plant Matrix to Molecular Function

edited by Chiara Magni

submission deadline 20 Oct 2025 | 5 articles | Viewed by 3799 | Submission Open

Keywords: plant matrix; agri-food biomasses; biochemistry; bioactive compounds

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research on Diabetes—2nd Edition

edited by

Alessandra Puddu

and

Davide Maggi

submission deadline 20 Oct 2025 | 3 articles | Viewed by 3744 | Submission Open

Keywords: diabetes; insulin; glucose metabolism; oxidative stress

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Mechanisms and Treatment of Migraine

edited by Noboru Imai

submission deadline 20 Oct 2025 | 1 articles | Viewed by 3724 | Submission Open

Keywords: migraine; nitric oxide synthase (NOS); neuropeptides; calcitonin gene-related peptide (CGRP); pituitary adenylate cyclase activating polypeptide (PACAP); molecular pathways; therapeutic targets; neurovascular condition

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Screening and Identification of Crop Abiotic Stress Tolerance Functional Genes

edited by

Liezhao Liu

submission deadline 20 Oct 2025 | 4 articles | Viewed by 3702 | Submission Open

Keywords: plant; abiotic stress; gene; identification; function

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms of Drug Discovery, Treatment, and Repurposing in Neuropsychiatric Disorders

edited by

Maria Bogdan

and

Liliana Mititelu-Tartau

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3680 | Submission Open

Keywords: animal models; neurodegeneration; neuropsychiatric disorders; neuroprotection; nanoparticles

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Heart Diseases: Molecular Pathogenesis, Biomarkers and Therapies

edited by

Nadia Aspromonte

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3664 | Submission Open

Keywords: heart diseases; biomarkers; molecular pathways; personalized medicine; interventional therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Neuroprotective Effects of Food Ingredients

edited by

Elena Ibáñez

and

Alejandro Cifuentes

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3630 | Submission Open

Keywords: neuroprotection; Parkinson; Alzheimer; bioactive compounds; agri-food by-products; chemical characterization; foodomics; metabolomics; molecular mechanisms

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Insight into Autoinflammatory Diseases

edited by

Ferenc Sipos

and

Györgyi Műzes

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3620 | Submission Open

Keywords: autoinflammation; autoimmunity; genetics; epigenetics; molecular pathogenesis; therapy; diagnosis; rare cases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Mechanism and Treatment Progress of Liver Disease

edited by Yohei Shirakami

submission deadline 20 Oct 2025 | 3 articles | Viewed by 3609 | Submission Open

Keywords: liver diseases; MASLD; alcoholic liver disease; liver cancer; viral hepatitis; sarcopenia

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Macrophages and Inflammation

edited by

Julia Kzhyshkowska

submission deadline 20 Oct 2025 | 1 articles | Viewed by 3584 | Submission Open

Keywords: innate immunity; transcriptional programs; epigenetics; immunometabolism; receptors; scavenging; cytokines; ROS

(This special issue belongs to the Section Molecular Immunology)

The Role of Macrophages in Cancers

edited by

Pierre Tennstedt

submission deadline 20 Oct 2025 | 3 articles | Viewed by 3565 | Submission Open

Keywords: tumor-associated macrophages; tumor microenvironment; monocytes; cancer; cancer therapy; bisphosphonates; cytokines; chemokines; immune response; therapeutic resistance; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Molecular Pathways and Therapeutic Strategies for Fibrotic Conditions

edited by

Morena Scotece

submission deadline 20 Oct 2025 | 3 articles | Viewed by 3546 | Submission Open

Keywords: fibrosis; fibrotic disorders; autoimmune diseases; cancer; adipose tissue fibrosis; repurposed drugs; gene therapies; cytokine-mediated pathways; anti-fibrotic therapies; systemic diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Inflammation and Cellular Senescence in Age-Related Diseases

edited by

Calogero Caruso

and

Giuseppina Candore

submission deadline 20 Oct 2025 | 1 articles | Viewed by 3492 | Submission Open

Keywords: age-related diseases; exposome; prevention; pathophysiology; pathogenesis; inflammation; senescence

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Newer Pharmacological Treatment Concepts for Patients with Acute Coronary Syndrome

edited by

Dimitrios Patoulias

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3483 | Submission Open

Keywords: acute coronary syndrome (ACS); molecular studies; antiplatelet; anticoagulant drugs; lipid-lowering therapies

(This special issue belongs to the Section Molecular Pharmacology)

Exploring the Molecular Basis of Cellular Responses to Microgravity-Induced Oxidative Stress

edited by

Caterina Morabito

and

Simone Guarnieri

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3392 | Submission Open

Keywords: microgravity; reactive oxygen species (ROS); oxidative damage; cellular antioxidant systems; cell metabolism; cell responses; molecular pathways; simulated microgravity; protective countermeasures

(This special issue belongs to the Section Molecular Biology)

Cell Pathways Underlying Neuronal Differentiation

edited by

Michela Ferrucci

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3381 | Submission Open

Keywords: neural progenitor cells; neuronal cell lines; induced pluripotent stem cells; neuronal phenotype; brain tumor cells

(This special issue belongs to the Section Molecular Neurobiology)

The Role of Phytohormones in Plant Biotic/Abiotic Stress Tolerance

edited by

Gastón Pizzio

submission deadline 20 Oct 2025 | 3 articles | Viewed by 3340 | Submission Open

Keywords: biotic/abiotic stress; phytohormone; resistance to stress

(This special issue belongs to the Section Molecular Plant Sciences)

Predictive and Diagnostic Biomarkers in Inflammatory and Neurodegenerative Diseases

edited by

Maria Morello

submission deadline 20 Oct 2025 | 1 articles | Viewed by 3323 | Submission Open

Keywords: Parkinson’ s disease; Alzheimer’ s disease; multiple sclerosis; amyotrophic lateral sclerosis; neurodegenerative diseases; inflammation amyloid plaques; tau; alpha-synuclein; cytokines; neurofilaments; vitamins

(This special issue belongs to the Section Molecular Neurobiology)

An Update for Photodynamic Therapy as a Versatile Tool for Biological Breakthroughs

edited by

Leandro M. O. Lourenço

João P. C. Tomé

and

Augusto C. Tomé

submission deadline 20 Oct 2025 | 1 articles | Viewed by 3319 | Submission Open

Keywords: photodynamic theraphy (aPDT); photochemistry; dyes; photosensitizers; porphyrins; phthalocyanines; and other derivatives; reactive oxygen species (ROS); singlet oxygen; cancer

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bioactive Peptides: Synthesis, Functions, and Medicinal Chemistry Applications

edited by

Giovanni Grazioso

submission deadline 20 Oct 2025 | 4 articles | Viewed by 3311 | Submission Open

Keywords: peptides; protein– protein interactions (PPIs); peptide intracellular delivery

(This special issue belongs to the Section Molecular Pharmacology)

New Insights into Plant and Insect Interactions (Second Edition)

edited by

Yonggen Lou

and Xiaoling Sun

submission deadline 20 Oct 2025 | 4 articles | Viewed by 3255 | Submission Open

Keywords: plant defense responses; elicitors; effectors; defense-related signaling; insect– plant interactions; tritrophic interactions; detoxification; defensive compounds; defensive genes

(This special issue belongs to the Section Molecular Plant Sciences)

Research on Cyclodextrin

edited by Valentina Giglio

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3219 | Submission Open

Keywords: drug delivery systems; polymeric cyclodextrin; pollution removal; sponge-like material; selective targeting systems; catalyst

(This special issue belongs to the Section Materials Science)

Molecular Studies of Mutations Related to Neurodegenerative Diseases

edited by

Fernando Cardona

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3114 | Submission Open

Keywords: SNPs; mutations; structural effects; transcriptional regulation; splicing; translational regulation; post-transcriptional regulation; post-translational regulation; haploinsufficiency; nonsense mediated decay; in silico analysis; experimental analysis; missense; nonsense; frameshift; epigenetics; non-coding; coding; function alteration; stability alteration

(This special issue belongs to the Section Molecular Neurobiology)

Antimicrobial Resistance, Molecular Mechanisms and Fight Strategies: 4th Edition

edited by

Francesca Micoli

and

Aleksandra Królicka

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3076 | Submission Open

Keywords: antimicrobial resistance; mechanisms of antimicrobial resistance; rapid antimicrobial-sensitive assays; drug discovery; antibiotics; vaccine; monoclonal antibodies; infectious diseases

(This special issue belongs to the Section Molecular Microbiology)

Mechanistic Insights into Cancer Immunotherapy and Immune-Related Adverse Events

edited by Noha Abdel-Wahab,

Bilal A. Siddiqui

and Kristen E. Pauken

submission deadline 20 Oct 2025 | 1 articles | Viewed by 3057 | Submission Open

Keywords: cancer immunotherapy; immune-related adverse events; biomarker; immune checkpoint inhibitor; cancer progression

(This special issue belongs to the Section Molecular Oncology)

Host Responses to Virus Infection

edited by Hideki Hayashi and Yoshinao Kubo

submission deadline 20 Oct 2025 | 3 articles | Viewed by 3043 | Submission Open

Keywords: viral infection; host reactions; interferon alpha and beta; interferon gamma; cytokines; vaccine; cytokine storm

(This special issue belongs to the Section Molecular Microbiology)

New Advances in Opioid Research

edited by Matthew E. Layton

submission deadline 20 Oct 2025 | 4 articles | Viewed by 2971 | Submission Open

Keywords: methadone; buprenorphine; hyperbaric oxygen; complementary/alternative/integrative treatments; patient-centered outcomes

(This special issue belongs to the Section Molecular Pharmacology)

Mitochondrial Metabolism Alterations in Health and Disease: 2nd Edition

edited by

Vincenza Dolce

Rosita Curcio

and

Graziantonio Lauria

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2963 | Submission Open

Keywords: mitochondrial Metabolism; mitochondrial disorders; cellular processes; dysregulation organisms’ physiology

(This special issue belongs to the Section Biochemistry)

Perspectives of Molecular Genetics and Genomics in Human Mendelian Diseases

edited by

Marta Rusmini

submission deadline 20 Oct 2025 | 3 articles | Viewed by 2956 | Submission Open

Keywords: functional genomics; omics; genetic disease; human; molecular mechanisms; genome editing; biomarkers; computational genomics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Brain Tumors: From Biomarkers to Novel Therapies

edited by

Okay Saydam

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2952 | Submission Open

Keywords: glioblastoma; medulloblastoma; meningioma; brain tumors; exosomes; circulating tumor markers; drug development and delivery technologies; molecular biology

(This special issue belongs to the Section Molecular Oncology)

Liver Fibrosis: Molecular Pathogenesis, Diagnosis and Treatment

edited by Manuel Morales-Ruiz

submission deadline 20 Oct 2025 | 2 articles | Viewed by 2915 | Submission Open

Keywords: liver fibrosis; cirrhosis; hepatic stellate cells; collagen; fibrogenic pathways; diagnosis of fibrosis; therapeutic strategies for liver disease; extracellular matrix remodeling; cell-to-cell interactions; fibrosis complications

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Neurodegenerative Disease: Looking for Oxidative Stress and Inflammation Mechanisms

edited by

Soraya L. Valles

submission deadline 20 Oct 2025 | 3 articles | Viewed by 2887 | Submission Open

Keywords: neurodegenerative disease; oxidative stress; inflammation mechanisms; neurons; astrocytes; microglia; oligodendroglia

(This special issue belongs to the Section Molecular Neurobiology)

Structural and Functional Polymer Materials in Biomedicine

edited by

Cristina Nistor

submission deadline 20 Oct 2025 | 2 articles | Viewed by 2815 | Submission Open

Keywords: polymer chemistry; biodegradable polymers; responsive polymers; nanocomposites; tissue engineering; smart materials; drug delivery systems; molecular structure; material characterization; biocompatibility

(This special issue belongs to the Section Materials Science)

Displaying special issue 1151-1200 on page 24 of 68.

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