Molecular Research on Diabetes—2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".
Deadline for manuscript submissions: 31 March 2025 | Viewed by 656
Special Issue Editors
Interests: diabetes; retinopathy; VEGF-A; IGF-1; advanced glycation end-products
Special Issues, Collections and Topics in MDPI journals
Interests: the role of caveoles in the insulin and IGF1 signal; new technologies in the treatment of diabetes mellitus; role of bariatric surgery in the regulation of metabolism
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Diabetes is a metabolic disease characterized by hyperglycemia. This chronic disorder raises the risk of microvascular as well as neurological disorders and contributes to the pathophysiology of diabetes complications. Type II diabetes accounts for 85–90% of all diabetic patients. There are a range of reasons as to why diabetes can occur: insulin resistance and β cell dysfunction are the main causative abnormalities; however, several mutations in the genes important for glucose homeostasis and β cell development have been related to the progress of hyperglycemia. In addition, environmental factors may influence the incidence of hyperglycemia. Although several studies have aimed to elucidate the molecular mechanisms underlying the development of diabetes and its complications, their precise pathophysiology is not completely understood. This Special Issue aims to collect the latest research on different biological processes and molecular mechanisms that cause diabetes, with a special emphasis on 1. insulin deficiency and insulin resistance, 2. impaired signaling pathways involved in glucose metabolism, 3. glucose transport and defects in transport activity, 4. post-translational modifications of the proteins involved in metabolism, 5. genetic defects associated with diabetes, 6. oxidative stress, and 7. pharmacological agents regulating glucose metabolism.
Dr. Alessandra Puddu
Dr. Davide Maggi
Guest Editors
Manuscript Submission Information
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Keywords
- diabetes
- insulin
- glucose metabolism
- oxidative stress
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