Molecular Aspects of Cartilage Biology

Dear Colleagues,

Articular cartilage, which is a highly specialized tissue, consists mainly of a dense extracellular matrix (ECM) comprising type II collagen fibers, proteoglycans, and water; this is alongside the dispersal of its distinctive cell type, chondrocytes, within the ECM. Chondrocytes play a crucial role in maintaining the cartilage matrix by producing and releasing collagen, proteoglycans, and the enzymes involved in cartilage metabolism. The metabolic function of chondrocytes is governed by the mechanical stress experienced by the tissue.

This Special Issue aims to explore cutting-edge advancements in Cartilage Biology, shedding light on the latest research, methodologies, and breakthroughs regarding the structure, function, and regeneration of cartilage tissues. We welcome contributions encompassing molecular mechanisms, chondrocytes interactions, and translational approaches that enhance our comprehension of cartilage-related disorders and potential therapeutic interventions.

Dr. Michela Geminiani
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• cartilage biology
• tissue regeneration
• molecular mechanisms
• chondrocytes
• cartilage disorders
• therapeutic interventions
• biomaterials