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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Pancreatic Ductal Adenocarcinoma: Unveiling Pathogenic Mechanisms and Pioneering Novel Therapeutic Strategies

edited by

Elena Astanina

submission deadline 20 Sep 2026 | 1 articles | Viewed by 816 | Submission Open

Keywords: pancreatic ductal adenocarcinoma; tumor microenvironment

(This special issue belongs to the Section Molecular Oncology)

Neutrophil Extracellular Traps (NETs) in Human Disease: From Molecular Mechanisms to Therapeutic Translation

edited by

Michael Boettcher

and Julia Elrod

submission deadline 20 Sep 2026 | 1 articles | Viewed by 810 | Submission Open

Keywords: neutrophil extracellular traps (NETs); molecular mechanisms; human disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Role of Quorum Sensing in Plant Microbiome: Advances and Prospects

edited by

Clarisse Brígido

submission deadline 20 Sep 2026 | Viewed by 785 | Submission Open

Keywords: quorum sensing; quorum quenching; rhizosphere signaling; signaling molecules; N-Acyl-L-homoserine lactones; AHLs; microbiome; chemical molecules; sustainable agriculture

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular and Cellular Mechanisms in Cardiovascular Disease

edited by

Paul Meakin

submission deadline 20 Sep 2026 | Viewed by 750 | Submission Open

Keywords: vascular cell function; atherosclerosis; diabetes-associated vascular complications; hypertension

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Collagen-Based Biomaterials in Tissue Engineering and Regenerative Medicine

edited by Martin Braun,

Selestina Gorgieva

and

Eva Filova

submission deadline 20 Sep 2026 | Viewed by 742 | Submission Open

Keywords: collagen; tissue engineering; advanced biomaterials; biodegradable composites; scaffolds; protein structure; biochemical analysis; material characterization; medical application; gelatine

(This special issue belongs to the Section Macromolecules)

Molecular Pharmacognosy: Bioactive Natural Products and Mechanistic Insights

edited by Luísa Mota Da Silva

submission deadline 20 Sep 2026 | 1 articles | Viewed by 719 | Submission Open

Keywords: pharmacognosy; natural products; bioactive compounds; phytochemistry; drug discovery

(This special issue belongs to the Section Molecular Pharmacology)

Antitumoral Properties of Natural and Synthetic Compounds

edited by

Manuel Valenzuela-Valderrama

submission deadline 20 Sep 2026 | Viewed by 686 | Submission Open

Keywords: anticancer agents; natural compounds; synthetic compounds; molecular mechanisms; translational research

(This special issue belongs to the Section Molecular Pharmacology)

Exploring Molecular-Scale and Nano-Scale Materials: Design, Characterization and Application

edited by Xiaogang Li

submission deadline 20 Sep 2026 | Viewed by 671 | Submission Open

Keywords: molecular scale; nano scale; material design and preparation; characterization; regulation; application

(This special issue belongs to the Section Molecular Nanoscience)

Natural Products—the Underestimated Source of New Solutions for the Innovative Antimicrobial Therapies

edited by

Piotr Okińczyc

, Jarosław Widelski and

Jakub Szperlik

submission deadline 20 Sep 2026 | Viewed by 667 | Submission Open

Keywords: plant; medicines; natural product; antimicrobial activity; drug resistance; chemical analysis

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Exploring Glia: New Insights into Neurobiology and Therapeutic Potential

edited by María de los Ángeles García-Robles

submission deadline 20 Sep 2026 | Viewed by 648 | Submission Open

Keywords: glial metabolism; astrocytes; microglia; oligodendrocytes; tanycytes; obesity; diabetes; metabolic disorders; neurogenesis; cognitive decline

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Signatures for Risk Stratification and Therapeutic Decision-Making in Primary and Recurrent Prostate Cancer

edited by

Chengfei Liu

submission deadline 20 Sep 2026 | 1 articles | Viewed by 643 | Submission Open

Keywords: molecular mechanisms; biomolecular research; mechanistic insights; molecular pathways; translational biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Thrombo-Inflammatory Signaling and Complications in Autoimmune Disorders

edited by

Alexandros Tsoupras

submission deadline 20 Sep 2026 | Viewed by 640 | Submission Open

Keywords: inflammation; thrombosis; platelets; coagulation; autoimmune disorders; rheumatoid arthritis; systematic erythematosus lupus; antiphospholipid syndrome; thrombo-inflammation; antithrombotic; antiplatelet

(This special issue belongs to the Section Molecular Immunology)

Novel Insights into the Molecular Mechanisms of Pancreatitis

edited by

Gi-Sang Bae

submission deadline 20 Sep 2026 | Viewed by 639 | Submission Open

Keywords: acute pancreatitis; chronic pancreatitis; pancreatic fibrosis; mechanisms; digestive enzymes; inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights into Fruit Crops Development

edited by

Xingguo Li

submission deadline 20 Sep 2026 | Viewed by 638 | Submission Open

Keywords: fruit crops; fruit tree; proteomics; genomics; metabolomics; biotic stress; abiotic stress

(This special issue belongs to the Section Molecular Plant Sciences)

Cytokines in Inflammatory Signaling: 3rd Edition

edited by

Waipo Chong

and

Daniela Novick

submission deadline 20 Sep 2026 | 1 articles | Viewed by 638 | Submission Open

Keywords: cytokines; inflammation; autoimmune diseases; immune homeostasis; signaling pathway; immunotherapy

(This special issue belongs to the Section Molecular Immunology)

Current Research on Structure and Functions of Ribosomal Proteins

edited by

Youri Timsit

submission deadline 20 Sep 2026 | 1 articles | Viewed by 637 | Submission Open

Keywords: protein synthesis; translation; translocation; dynamics; folding; network; assembly; evolution

(This special issue belongs to the Section Molecular Biology)

Synthesis and Application of Organic Antibacterial Agents

edited by

Barbara Dmochowska

submission deadline 20 Sep 2026 | Viewed by 627 | Submission Open

Keywords: organic antibacterial compounds; synthesis; natural organic compounds; biological activity; active compounds; biological applications

(This special issue belongs to the Section Biochemistry)

Effects of Xenobiotic Exposure on Human Health: A Molecular Perspective

edited by

Maria Lisa Garavaglia

submission deadline 20 Sep 2026 | Viewed by 611 | Submission Open

Keywords: xenobiotic exposure; human health; toxic effects; environmental chemicals; molecular research

(This special issue belongs to the Section Molecular Toxicology)

Recent Progress and Perspectives in Natural Products

edited by

Hanae Naceiri Mrabti

and

Naoufal El Hachlafi

submission deadline 20 Sep 2026 | Viewed by 610 | Submission Open

Keywords: natural products; bioactive compounds; pharmacology; nutrition; biotechnology

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Cellular Plasticity in Health and Diseases

edited by

Giovanni Barillari

submission deadline 20 Sep 2026 | Viewed by 586 | Submission Open

Keywords: stem cells; cytokines; extracellular matrix; cell differentiation; cell locomotion; cell growth; tissue repair; chronic inflammation; dysplasia; hyperplasia; premalignant lesions; cancer

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Neuro and Immune Mechanisms Behind Cannabinoids Effects

edited by

Babak Baban

submission deadline 20 Sep 2026 | Viewed by 570 | Submission Open

Keywords: cannabinoids; neuroinflammation; endocannabinoid system (ECS); non-cannabinoid receptors; immune modulation; synaptic plasticity

(This special issue belongs to the Section Biochemistry)

Development Biology of Immune Cells

edited by Jacek Z. Kubiak

submission deadline 20 Sep 2026 | Viewed by 550 | Submission Open

Keywords: immune cell development; macrophages; monocytes; B-cells; T-cells; dendritic cells; NK cells

(This special issue belongs to the Section Molecular Immunology)

Molecular Mechanisms of Plant Abiotic Stress Tolerance: 3rd Edition

edited by

Michael Moustakas

submission deadline 20 Sep 2026 | Viewed by 543 | Submission Open

Keywords: acclimation; drought; salinity; pesticides; high–low temperature; high–low light intensity; nutrient deficiencies; heavy metals; UV radiation; photosynthetic efficiency; ROS; antioxidant mechanisms; redox regulation

(This special issue belongs to the Section Molecular Plant Sciences)

Machine Learning in RNA and Chromatin Dynamics

edited by Haopeng Yu

submission deadline 20 Sep 2026 | Viewed by 530 | Submission Open

Keywords: machine learning; chromatin architecture; RNA dynamics; genomic foundation models; computational biology

(This special issue belongs to the Section Molecular Biology)

New Advances in Type 2 Diabetes and Its Complications: 2nd Edition

edited by

Anca Pantea Stoian

submission deadline 20 Sep 2026 | Viewed by 517 | Submission Open

Keywords: diabetes type 2; diabetes complications; pathophysiology of type 2 diabetes; new diabetes treatment; cardiovascular disease; stroke; peripheral artery disease; chronic kidney disease; retinopathy; neuropathy; non-alcoholic fatty liver disease in diabetes

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Environmental Exposures and Emerging Mechanisms in Chronic Obstructive Pulmonary Disease: From Pathogenesis to Precision Therapeutics

edited by

Abderrazzak Bentaher

submission deadline 20 Sep 2026 | Viewed by 515 | Submission Open

Keywords: chronic obstructive pulmonary disease; environmental exposures; disease pathogenesis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Flexible Sensors for Biomedical Application

edited by

Jimin Lee

submission deadline 20 Sep 2026 | Viewed by 505 | Submission Open

Keywords: biomedical applications; molecular diagnostics; molecular recognition mechanisms; biosensors; electrochemical sensing; nanomaterials for sensing; implantable sensors; soft bioelectronics

(This special issue belongs to the Section Biochemistry)

The Role of Polyphenols and Polysaccharides in Human Diseases

edited by

Francisco Les

submission deadline 20 Sep 2026 | Viewed by 501 | Submission Open

Keywords: polyphenols; polysaccharides; bioactive compounds; chronic diseases prevention; functional foods

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Transcriptional Regulation and Its Misregulation in Human Diseases: Recent Insights

edited by

Amelia Casamassimi

and

Monica Rienzo

submission deadline 20 Sep 2026 | Viewed by 493 | Submission Open

Keywords: transcription machinery; transcription (co)factors; chromatin regulators; splicing regulators; noncoding RNAs; transcription misregulation; genetic alterations; human diseases; transcriptome profiling; bioinformatics analysis

(This special issue belongs to the Section Molecular Biology)

Angiogenin: From Molecular Mechanisms to Clinical Implications

edited by

Iogann Tolbatov

submission deadline 20 Sep 2026 | Viewed by 477 | Submission Open

Keywords: angiogenin; angiogenesis; neuroprotection; cancer; neurodegeneration; biomarker; therapeutic target

(This special issue belongs to the Section Biochemistry)

Molecular Pathways and Mechanisms of Lung Injury: From Environmental Agents to Clinical Implications

edited by

Maria Lisa Garavaglia

and Cristina Porta

submission deadline 20 Sep 2026 | Viewed by 470 | Submission Open

Keywords: lung injury; lung cancer; pulmonary fibrosis; chronic obstructive pulmonary disease; acute respiratory distress syndrome; environmental pollutants and toxins; molecular and cellular mechanisms; biomarkers; therapeutic approaches

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Autophagy and Viral Infections: The Era of New Therapeutical Strategies

edited by

Marisa Granato

submission deadline 20 Sep 2026 | Viewed by 457 | Submission Open

Keywords: autophagy; macroautophagy system; virus; viral infection; influenzae virus

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bioactive Compounds in Bee Products: Chemistry, Mechanisms of Action and Nutritional Applications

edited by

Jarosław Widelski

and

Ioanna Chinou

submission deadline 20 Sep 2026 | Viewed by 448 | Submission Open

Keywords: honey; propolis; royal jelly; polyphenols; nutritional properties; bioactivity; analytical and isolation methods; bee pollen

(This special issue belongs to the Section Bioactives and Nutraceuticals)

New Advances in Natural Product Synthesis and Emerging Biotechnology Applications

edited by Katarzyna Kotwica-Mojzych

submission deadline 20 Sep 2026 | Viewed by 438 | Submission Open

Keywords: natural compounds; natural product synthesis; chemical analysis; molecular technologies; biotechnology

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advanced Composite Materials: Molecular Design and Applications

edited by Fan Yang

submission deadline 20 Sep 2026 | Viewed by 436 | Submission Open

Keywords: multifunctional applications; mechanical and physical properties; extreme environments; molecular dynamics analysis; composite molecular design, preparation, simulation, and characterization

(This special issue belongs to the Section Materials Science)

The Role of the Gut and Oral Microbiota in Neurodevelopment: Molecular Biological Insights

edited by Ioannis Alexandros Charitos

submission deadline 20 Sep 2026 | Viewed by 424 | Submission Open

Keywords: neuroscience; central nervous system; peripheral nervous system; human microbiota; metabolome; gut–oral-microbiota–brain axis; neurodevelopment disorders; cognitive modulation; neurodegenerative diseases; psychobiotics

(This special issue belongs to the Section Molecular Microbiology)

Age-Dependence of Neuroimmune Reactions

edited by

Babak Baban

submission deadline 20 Sep 2026 | Viewed by 424 | Submission Open

Keywords: age; neuroimmune dynamics; neuroimmune interaction; immune system; the central nervous system; age-related neuroinflammation; neurodegenerative diseases

(This special issue belongs to the Section Molecular Immunology)

Female and Male Fertility: From Diseases to Current Trends and Research Developments

edited by Fabio Barra

submission deadline 20 Sep 2026 | Viewed by 421 | Submission Open

Keywords: female infertility; male infertility; reproductive health; reproductive outcomes; assisted reproductive technologies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Theranostic Application of Reactive Oxygen Species-Sensitive Nanocarriers

edited by

Young-Il Jeong

submission deadline 20 Sep 2026 | Viewed by 418 | Submission Open

Keywords: ROS generation; ROS detection; ROS-sensitive nanoparticles; Photodynamic therapy (PDT)

(This special issue belongs to the Section Molecular Nanoscience)

Polymer Materials Related to Food Packaging

edited by

Rosie Yagmur Yegin

submission deadline 20 Sep 2026 | Viewed by 418 | Submission Open

Keywords: polymeric materials; food packaging; biodegradable polymers; active packaging; intelligent packaging; nanocomposites; sustainability; circular economy; barrier properties; life cycle assessment

(This special issue belongs to the Section Macromolecules)

Advances in Animal Nutrition and Muscle Biology

edited by Usuk Jung

submission deadline 20 Sep 2026 | Viewed by 418 | Submission Open

Keywords: animal nutrition; metabolic regulation; molecular biology; molecular mechanisms; skeletal muscle; intramusculuar fat; skeletal muscle fibrosis

(This special issue belongs to the Section Molecular Biology)

Advances in Nasopharyngeal Carcinoma Immunology, Epigenetics, and Therapy

edited by

Wei Dai

submission deadline 20 Sep 2026 | Viewed by 418 | Submission Open

Keywords: nasopharyngeal carcinoma (NPC); epstein–barr virus (EBV); cancer epigenomics; virus–host interaction; tumor microenvironment (TME); immunotherapy; targeted therapy; biomarker; metastasis; radiotherapy resistance

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Immune Microenvironment and Tissue Remodeling in Oral Diseases and Oral Cancer

edited by

Aiman Ali

submission deadline 20 Sep 2026 | Viewed by 410 | Submission Open

Keywords: immune microenvironment; oral cancer; oral diseases; tissue remodeling; molecular signaling pathways

(This special issue belongs to the Section Molecular Immunology)

Role of Extracellular Vesicles in Immune Regulation

edited by Rachel Crossland

submission deadline 20 Sep 2026 | Viewed by 410 | Submission Open

Keywords: extracellular vesicle; immune regulation; immunomodulation; antigen presentation; inflammation; autoimmunity

(This special issue belongs to the Section Molecular Immunology)

Down Syndrome: From Molecular Mechanisms to Therapeutic Strategies

edited by Amy Feldman Lewanda

submission deadline 20 Sep 2026 | Viewed by 407 | Submission Open

Keywords: down syndrome; Trisomy 21; molecular mechanisms; therapeutic strategies; neurodegeneration; comorbidities; animal models

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms and Biomarkers in Cardiovascular Disease: Hepatocardiac and Systemic Interactions

edited by

Wioletta Szczurek-Wasilewicz

submission deadline 20 Sep 2026 | Viewed by 390 | Submission Open

Keywords: hepatocardiac interactions; hepatic biomarkers; cardiovascular disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Strategies for Enhancing Skeletal Muscle Recovery and Regeneration in Health and Disease Conditions

edited by

Elen Miyabara

and

Atsushi Asakura

submission deadline 20 Sep 2026 | Viewed by 383 | Submission Open

Keywords: skeletal muscle; regeneration; muscle wasting; aging; muscle diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Current Research on Neuroprotective Phytochemicals and Their Multi-Target Mechanisms

edited by

Gerardo Álvarez-Rivera

and

Alejandro Cifuentes

submission deadline 20 Sep 2026 | Viewed by 375 | Submission Open

Keywords: Alzheimer’s disease; neuroprotective phytochemicals; green extraction; technologies; blood–brain barrier permeability; bioavailability; multi-target mechanisms; omics approaches; nanodelivery systems; brain health; neuroprotection

(This special issue belongs to the Section Molecular Neurobiology)

Advanced Molecular Research on Diabetes Pharmacology

edited by

Ioanna A. Anastasiou

submission deadline 20 Sep 2026 | Viewed by 374 | Submission Open

Keywords: diabetes; pharmacology; antidiabetic drugs; insulin therapy; SGLT2 inhibitors; GLP-1 receptor agonists; combination therapy; personalized medicine; drug development

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Perspectives on Female Infertility and Fertility

edited by

Seung-Yup Ku

submission deadline 20 Sep 2026 | Viewed by 371 | Submission Open

Keywords: female infertility; molecular mechanisms of reproduction; oocyte maturation and development; reproductive aging; polycystic ovary syndrome; endometriosis; epigenetic regulation in reproduction; oxidative stress and mitochondrial dysfunction; reproductive biomarkers; precision medicine and regenerative therapies

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Displaying special issue 1051-1100 on page 22 of 65.

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