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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancements in Metal-Organic Frameworks: Synthesis, Properties, and Applications

edited by

Maria Milanova

submission deadline 30 Sep 2025 | Viewed by 75 | Submission Open

Keywords: metal– organic frameworks; hybrid materials; powder X-ray diffraction; single-crystal diffraction; synthesis approach; gas separation; adsorbents; sensors; catalysts; separation; magnetism; LEDs

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Magnetic Nanoparticles: From Synthesis and Modification to Biomedical Applications

edited by

Ahmet Kertmen

submission deadline 30 Sep 2025 | Viewed by 75 | Submission Open

Keywords: magnetite nanoparticles; colloidal interactions; X-ray characterizations; biomedical applications; method development; imaging

(This special issue belongs to the Section Molecular Nanoscience)

Neuroendocrine Integration of Stress and Reproduction

edited by Maria Bernardete Cordeiro De Sousa

submission deadline 30 Sep 2025 | Viewed by 74 | Submission Open

Keywords: HPA axis; HPG axis; stress and reproduction; neuroendocrine regulation; cortisol and fertility; neuropeptides; epigenetics; reproductive dysfunction

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Research on Microbial Natural Products

edited by Wenli Li

submission deadline 30 Sep 2025 | Viewed by 74 | Submission Open

Keywords: microbial natural products; biosynthetic gene clusters; structural elucidation; metabolic engineering; synthetic biology; bioactivity profiling; sustainable biomanufacturing

(This special issue belongs to the Section Molecular Microbiology)

The Role of Extracellular Vesicles in Disease and Therapeutic Applications

edited by Sunyoung Park

submission deadline 30 Sep 2025 | Viewed by 72 | Submission Open

Keywords: extracellular vesicles (EVs); disease biomarkers; EV-based therapeutics; cancer diagnosis; drug delivery; immune modulation; regenerative medicine

(This special issue belongs to the Section Molecular Biology)

Molecular Insight into Catalysis of Nanomaterials

edited by Dandan Liu

submission deadline 30 Sep 2025 | Viewed by 72 | Submission Open

Keywords: nanomaterial catalyst; thermal catalysis; photocatalysis; electrocatalysis; DFT calculation

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Mechanisms of Hypertension

edited by Pedro A. José

submission deadline 30 Sep 2025 | Viewed by 72 | Submission Open

Keywords: salt sensitivity; inverse salt sensitivity; epigenetics; genetics; organ-to-organ communication

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Endocrine Disruptors in Immune Diseases

edited by

Eui-Bae Jeung

submission deadline 30 Sep 2025 | Viewed by 72 | Submission Open

Keywords: endocrine disruptors; immune disease; cytokine signaling; autoimmunity; immunotoxicity; epigenetic modulation; hormone receptors; inflammation; environmental toxicology; EDC exposure

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Regulatory Mechanisms in Kidney Development and Function

edited by Gary F. Gerlach

submission deadline 30 Sep 2025 | Viewed by 71 | Submission Open

Keywords: drosophila nephrocyte; zebrafish pronephros; mesonephros; murine nephrogenesis; slit diaphragm; podocytes; junctions; tubule; mesenchymal-to-epithelia transition (MET); epithelial-to-mesenchymal transition (EMT); tubule segmentation; transcription factors; signaling pathways; foot processes; cytoskeleton; brush boarder; intercalated cells; renin angiotensin; diabetic kidney disease; podocytopathies; FSGS; minimal change disease; IgAN

(This special issue belongs to the Section Molecular Biology)

Advances in Biological Breeding and Molecular Biology of Tropical Crops

edited by Yongzan Wei

submission deadline 30 Sep 2025 | Viewed by 71 | Submission Open

Keywords: tropical crops; biological breeding; tropical fruit; molecular biology; gene editing; transcrip-tional regulation; genomics

(This special issue belongs to the Section Molecular Plant Sciences)

The Role of Cytokines in Inflammation and Diseases

edited by

Keiichi Yamanaka

submission deadline 30 Sep 2025 | Viewed by 71 | Submission Open

Keywords: inflammation; cytokine; complication; systemic inflammation; internal organ

(This special issue belongs to the Section Molecular Immunology)

Molecular Advances in Detection and Analysis of Microbial Pathogens

edited by Ignacio Garcia

submission deadline 30 Sep 2025 | Viewed by 71 | Submission Open

Keywords: molecular diagnostics; antimicrobial resistance; emerging pathogens; bioinformatics; metagenomics; clinical microbiology; environmental microbiology; surveillance; outbreak detection

(This special issue belongs to the Section Molecular Microbiology)

Biochemical Advancements in Filler Technology and Their Impact on Tissue Engineering

edited by Samuel J. Lin

submission deadline 30 Sep 2025 | Viewed by 70 | Submission Open

Keywords: biochemical filler technology; tissue regeneration; bioactive materials; injectable scaffolds; molecular signaling in tissue engineering; biomaterials for soft tissue repair; filler– cell interactions; regenerative esthetics

(This special issue belongs to the Section Biochemistry)

Antimicrobial Agents and the Quest for Resistance Breakthroughs

edited by

Inês Bártolo

submission deadline 30 Sep 2025 | Viewed by 70 | Submission Open

Keywords: drug resistance; antimicrobial resistance (AMR); drug-resistant bacteria; drug-resistant viruses; drug-resistant fungi; drug-resistant parasite; drug resistance biomolecular studies; mechanism of resistance; novel antimicrobial agents; treatment of infectious diseases

(This special issue belongs to the Section Molecular Pharmacology)

Advances in the Molecular Biology of Lipids and Mitochondria

edited by

Alejandra Espinosa

submission deadline 30 Sep 2025 | Viewed by 70 | Submission Open

Keywords: lipids; lipid transport mechanisms; lipid peroxidation; mitochondrial integrity; bioenergetics; mitochondrial phospholipid

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Autosomal Dominant Polycystic Kidney Disease (ADPKD): Molecular Mechanism, Management and Therapy

edited by

Maria Teresa Sciarrone Alibrandi

submission deadline 30 Sep 2025 | Viewed by 69 | Submission Open

Keywords: autosomal dominant polycystic kidney disease; ADPKD progression; cystic kidney disease; cardiovascular complications in ADPKD; biomarkers of ADPKD; genetics of polycystic kidney disease; renal imaging; targeted therapies in ADPKD

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Plant Breeding Strategies: Employment of Plant Adaptation Mechanisms to Biotic and Abiotic Stresses

edited by

Vidmantas Bendokas

submission deadline 30 Sep 2025 | Viewed by 69 | Submission Open

Keywords: marker-assisted selection; molecular breeding; whole-transcriptome analysis; RNA sequencing; DNA sequencing; plant stress response

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Surfactant Systems: Thermodynamics, Molecular Interactions, and Applications

edited by

Mihalj Poša

submission deadline 30 Sep 2025 | Viewed by 68 | Submission Open

Keywords: micelles; mixed micelles; thermodynamic functions of micellization; micellar solubilization; enthalpy– entropy compensation; boundary surface; Langmuir isotherm; theoretical models

(This special issue belongs to the Section Biochemistry)

CD8⁺ T Cells in the Cancer Immunity Cycle: Mechanisms, Barriers, and Therapeutic Opportunities

edited by Wael Traboulsi

submission deadline 30 Sep 2025 | Viewed by 68 | Submission Open

Keywords: CD8+ T cell; cancer immunotherapy; checkpoint inhibitor; CAR-T cell therapy; CD8 differentiation; epigenetic regulation; metabolism; exhaustion; dysfonctional CD8+ T cell

(This special issue belongs to the Section Molecular Immunology)

Influenza Pathogenesis and Vaccine Development

edited by

Awad Shehata

submission deadline 30 Sep 2025 | Viewed by 65 | Submission Open

Keywords: avian influenza; influenza virus; influenza surveillance; interspecies transmission; immune response; pandemic preparedness; pathogenesis; One Health; universal vaccines; vaccine development; viral adaptation; viral evolution; zoonotic infections

(This special issue belongs to the Section Molecular Microbiology)

Serum Amyloid A: Established Roles and Emerging Questions in Health and Disease

edited by Preetha Shridas

submission deadline 30 Sep 2025 | Viewed by 65 | Submission Open

Keywords: Serum Amyloid A; high-density lipoprotein; acute inflammation; chronic inflammatory

(This special issue belongs to the Section Biochemistry)

Molecular Mechanisms of Mitochondrial Neurodegenerative Diseases

edited by

Matteo Calcagnile

and Paola Pontieri

submission deadline 30 Sep 2025 | Viewed by 65 | Submission Open

Keywords: mitochondrial disease; nuclear genome; mitochondrial genome; human MRP genes; MRPL44; NAM9; GEP3; Alzheimer’ s disease; Parkinson’ s disease; yeast and C. elegans model organisms

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Progress in Male Reproduction

edited by

Ahmet Ayaz

submission deadline 30 Sep 2025 | Viewed by 64 | Submission Open

Keywords: male infertility; spermatogenesis; epigenetics; sperm function; testicular molecular biology; bioinformatics; reproductive genomics

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Novel Biomaterials and Technologies for Environmental Science

edited by Cátia Venâncio

submission deadline 30 Sep 2025 | Viewed by 63 | Submission Open

Keywords: biomass conversion; bio-based materials; circular bioeconomy; sustainable manufacturing; eco-friendly materials; environmental sustainability

(This special issue belongs to the Section Materials Science)

Natural Bioactive Compounds for Human Health, 3rd Edition

edited by

Hongjie Zhang

submission deadline 30 Sep 2025 | Viewed by 63 | Submission Open

Keywords: natural bioactive plant products; biological and pharmacological activity; natural plant drug discovery and development; nutraceuticals; botanical dietary supplement

(This special issue belongs to the Section Molecular Pharmacology)

Eco-Conscious Therapeutics: Molecular Foundations and Future Directions in Green Medicine

edited by

Adi Lahat

and

Kassem Sharif

submission deadline 30 Sep 2025 | Viewed by 62 | Submission Open

Keywords: green medicine; molecular therapeutics; sustainable healthcare; biomarker profiling; predictive toxicology; eco-friendly drug design; environmental impact; biodegradable materials

(This special issue belongs to the Section Molecular Toxicology)

Latest Research on Probiotics: Molecular Mechanisms and Health Applications

edited by

Ying Zhang

submission deadline 30 Sep 2025 | Viewed by 61 | Submission Open

Keywords: probiotics; molecular signaling; microbial– host crosstalk; metabolomic profiling; microbiome modulation; metabolite– receptor interaction

(This special issue belongs to the Section Molecular Microbiology)

Molecular Pathology and Drug Therapy in Orthopedic Injuries

edited by Dror Robinson

submission deadline 30 Sep 2025 | Viewed by 58 | Submission Open

Keywords: molecular therapy; regenerative medicine; stem cell therapy; exosomes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanism and Pharmacological Target of Neuroprotection

edited by

Pietro Cacialli

submission deadline 30 Sep 2025 | Viewed by 58 | Submission Open

Keywords: neurodegeneration; animal model; brain regeneration; pharmacological drug; molecular analysis

(This special issue belongs to the Section Molecular Neurobiology)

Machine Learning Approaches in Drug Molecule Design

edited by

Bing Niu

submission deadline 30 Sep 2025 | Viewed by 58 | Submission Open

Keywords: machine learning; drug design; deep learning; virtual screening; QSAR; molecular property prediction; de novo drug design; pharmacokinetics; computational chemistry; drug discovery

(This special issue belongs to the Section Molecular Informatics)

Advances in Plant–Pathogen Interactions (4th Edition)

edited by

Fucheng Lin

submission deadline 30 Sep 2025 | Viewed by 58 | Submission Open

Keywords: host; effection; pathogenicity; pathogen; plant immunity; interactions

(This special issue belongs to the Section Molecular Plant Sciences)

Metal Toxicity and Particle Toxicity

edited by Alicja Piotrowska-Niczyporuk

submission deadline 30 Sep 2025 | Viewed by 57 | Submission Open

Keywords: metals; particles; toxicity; microplastic; environment pollution; animals; plants; algae

(This special issue belongs to the Section Molecular Toxicology)

New Advances of Magnetic Nanomaterials in Biomedical Applications

edited by

Izabell Craciunescu

submission deadline 30 Sep 2025 | Viewed by 57 | Submission Open

Keywords: magnetic nanomaterials; biomedical applications; drug delivery systems; magnetic hyperthermia; magnetic resonance imaging (MRI)

(This special issue belongs to the Section Materials Science)

Hydrogels and Nanogels: Revolutionizing Drug Delivery and Disease Detection

edited by Enrico Gallo

submission deadline 30 Sep 2025 | Viewed by 57 | Submission Open

Keywords: hydrogel and nanogel networks; supramolecular systems; hydrogel synthesis and analysis; nanogel preparation and characterization; nanostructured fibers; multiphase gels; biomedicine applications; supramolecular probes for imaging; hydrogels and nanogels as drug release systems; coatings and surface treatments; polymeric systems; peptide-based supramolecular systems

(This special issue belongs to the Section Materials Science)

Microbial Interactions with Insect Hosts: Mechanisms, Evolution and Ecological Implications

edited by Jin-Hua Xiao

submission deadline 30 Sep 2025 | Viewed by 54 | Submission Open

Keywords: insect-microbe symbiosis; host-microbe coevolution; microbial-mediated behavior; insect adaptive evolution; cross-domain evolution

(This special issue belongs to the Section Molecular Microbiology)

New Horizons in the Diagnosis of Gynecological Malignancies

edited by Nina Montik

submission deadline 30 Sep 2025 | Viewed by 52 | Submission Open

Keywords: gynecological cancers; early diagnosis; biomarkers; molecular profiling; liquid biopsy; imaging techniques; artificial intelligence; translational research; personalized medicine; prognostic evaluation

(This special issue belongs to the Section Molecular Oncology)

Exploring Molecular Advances in Contaminant Removal

edited by Dexin Liu

submission deadline 30 Sep 2025 | Viewed by 52 | Submission Open

Keywords: removing pollutants; novel adsorbents; catalyst molecules; environmental science and technology

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Molecular and Cellular Pathways Involved in Age-Related Musculoskeletal Disorders

edited by

Abhishek Chandra

and Neha Dole

submission deadline 1 Oct 2025 | Viewed by 122 | Submission Open

Keywords: musculoskeletal disorders; cellular senescence; aging; genetic mutations; oxidative stress; mitochondrial dysfunction; bone homeostasis

(This special issue belongs to the Section Molecular Biology)

Surfactants: Design, Synthesis and Application

edited by

Urszula Bazylinska

submission deadline 9 Oct 2025 | Viewed by 148 | Submission Open

Keywords: surfactants; adsorption phenomena; critical micellar concentration (CMC); hydrophilic– lipophilic balance (HLB); critical packing parameter (CPP); emulsion formulations; vesicular and non-vesicular origin nanocarriers; drug delivery; theranostics

(This special issue belongs to the Section Materials Science)

A Metabolomics Approach to Tackling Toxicological and Pharmacological Issues: 2nd Edition

edited by

Nuno G. Oliveira

and

Paula Guedes de Pinho

submission deadline 10 Oct 2025 | 2 articles | Viewed by 5095 | Submission Open

Keywords: metabolomics; metabolites; drugs; contaminants; xenobiotics; toxicity; pharmacology; toxicology

(This special issue belongs to the Section Molecular Toxicology)

Chlamydia trachomatis Pathogenicity and Disease (Third Edition)

edited by

Rosa Sessa

and

Marisa Di Pietro

submission deadline 10 Oct 2025 | Viewed by 154 | Submission Open

Keywords: Chlamydia trachomatis; virulence factors; host susceptibility or resistance; innate and adaptive immune responses; genetic studies; cervico-vaginal microbiota; clinical outcomes with molecular study

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Graphene-Based Nanocomposites and Perspectives on Their Design

edited by Aleksey E. Kuznetsov

submission deadline 10 Oct 2025 | Viewed by 136 | Submission Open

Keywords: graphene; graphene oxide; nanocomposite; synthesis; computational study; characterization; application; design

(This special issue belongs to the Section Molecular Nanoscience)

MDSCs in Health and Disease

edited by

Víctor Sánchez-Margalet

submission deadline 10 Oct 2025 | Viewed by 85 | Submission Open

Keywords: MDSCs; inflammation; immune regulation; cancer; autoimmune diseases; pregnancy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Fundamental and Practical Perspectives in Regenerative Medicine: Proceedings of the VI National Congress of Regenerative Medicine (2024)

edited by

Vsevolod A. Tkachuk

and

Pavel Makarevich

submission deadline 15 Oct 2025 | 13 articles | Viewed by 11586 | Submission Open

Keywords: regenerative medicine; stem cell; gene therapy; cell therapy; tissue engineering

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Drug Discovery: Natural Products and Compounds

edited by

Vincenzo Summa

Maria Maisto

and

Vincenzo Piccolo

submission deadline 15 Oct 2025 | Viewed by 364 | Submission Open

Keywords: natural products; drug discovery; bioactive compounds; phytochemicals; marine natural compounds; microorganisms; structure– activity relationships (SARs); pharmacological activity; cheminformatics; metabolomics

(This special issue belongs to the Section Molecular Pharmacology)

Genetics of Human Disease: Emphasis on X-Linked Diseases and Clinical Practice

edited by Antonella La Russa

submission deadline 15 Oct 2025 | Viewed by 320 | Submission Open

Keywords: rare diseases; X-linked disease; X chromosome inactivation (XCI); mosaicism; epigenome; undiagnosed rare diseases; phenotype– genotype correlations; biomarkers; personalized medicine; precision medicine

(This special issue belongs to the Section Molecular Genetics and Genomics)

The Natural Products for Cancer Therapy

edited by María Jesus Rodríguez-Yoldi

submission deadline 15 Oct 2025 | Viewed by 83 | Submission Open

Keywords: apoptosis; antioxidant; anti-inflammatory; cancer; cell viability; food-by-products; natural products; polyphenols

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Targeted Therapy for Immune Diseases

edited by

Alexey Sarapultsev

submission deadline 20 Oct 2025 | 14 articles | Viewed by 34911 | Submission Open

Keywords: targeted therapy; immune diseases; biologics; immunotherapy; precision medicine; nanoparticles; biomarkers

(This special issue belongs to the Section Molecular Immunology)

New Players in the Research of Oxidative Stress and Cancer

edited by

Ana Čipak Gašparović

submission deadline 20 Oct 2025 | 9 articles | Viewed by 34564 | Submission Open

Keywords: cancer; oxidative stress; biomarkes; redox signaling pathway; therapy resistance

(This special issue belongs to the Section Biochemistry)

Synthesis and Molecular Research of Drugs for Skin Diseases and Cosmetic Ingredients

edited by

Elzbieta Budzisz

and Paulina Mucha

submission deadline 20 Oct 2025 | 5 articles | Viewed by 27567 | Submission Open

Keywords: skin diseases; skin cancers; aging; pathogenesis; topical dermatological therapy; systemic dermatological therapy; cosmetic ingredients; molecular mechanism; drugs design and synthesis; molecular mechanism

(This special issue belongs to the Section Molecular Pharmacology)

Displaying special issue 1051-1100 on page 22 of 68.

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