Neutrophil Extracellular Traps (NETs) in Human Disease: From Molecular Mechanisms to Therapeutic Translation

Dear Colleagues,

This Special Issue invites original research papers and reviews on the molecular machinery of neutrophil extracellular traps (NETs) in the context of human disease. We also welcome studies at the interface of surgery and oncology, including perioperative NET induction, ischemia–reperfusion and biomaterial/implant interactions, wound and anastomotic healing, adhesion formation, immunothrombosis, and postoperative complications. In oncology, we seek mechanistic work on how NETs shape the tumor microenvironment, capture circulating tumor cells, promote metastasis, modulate responses to chemo-/radiotherapy and immunotherapy, and affect outcomes after oncologic surgery. Beyond oncology, submissions on infection and sepsis, cardio-/cerebrovascular disease, pulmonary injury/ARDS, autoimmunity, metabolic disease, renal/hepatic injury, neuroinflammation, and maternal–fetal medicine are encouraged. Translational contributions on diagnostics and biomarkers, device/implant surface engineering, and therapeutic strategies, including preclinical and clinical studies, are especially welcome.

Prof. Dr. Michael Boettcher
Dr. Julia Elrod
Guest Editors

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