Hepatocardiac Interactions and the Utility of Hepatic Biomarkers in Cardiovascular Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 31
Special Issue Editor
2. 2nd Department of Cardiology and Angiology, Silesian Center for Heart Diseases, 41-800 Zabrze, Poland
Interests: heart failure; cardiovascular disease; biomarkers; pharmacological treatment; drug interactions; risk stratification; prognostic scales
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue of IJMS, entitled “Hepatocardiac Interactions and the Utility of Hepatic Biomarkers in Cardiovascular Disease”, will focus on recent advances in our molecular understanding of interaction between the liver and heart. Hepatic dysfunction is frequently observed in patients with cardiovascular disease as a consequence of systemic venous congestion, reduced cardiac output, and persistent inflammation. These pathological states initiate complex molecular cascades that involve endothelial dysfunction, hepatocellular hypoxia, mitochondrial impairment, and the activation of profibrotic and inflammatory signaling pathways. As a result, structural and functional liver dysfunction may not only reflect the severity of cardiac dysfunction, but also contribute to worse cardiovascular outcomes, creating a deleterious feedback loop. In this context, further research is needed to enhance our understanding of cardio-hepatic interactions. We welcome original articles and reviews that address cellular and molecular pathways, experimental models, and biomarker-based risk stratification in cardiovascular disease, as well as articles that identify novel therapeutic targets.
Dr. Wioletta Szczurek-Wasilewicz
Guest Editor
Manuscript Submission Information
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Keywords
- hepatocardiac interactions
- hepatic biomarkers
- cardiovascular disease
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