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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Mechanisms and Pathophysiology of Cystic Fibrosis

edited by

Stefanie Krick

and George M. Solomon

submission deadline 20 Sep 2025 | 1 articles | Viewed by 3114 | Submission Open

Keywords: cystic fibrosis; aging; CF airway disease; CF complications; CF molecular pathogenesis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Molecular Research on the Diagnosis and Treatment of Chronic Liver Diseases

edited by

Hirayuki Enomoto

submission deadline 20 Sep 2025 | 2 articles | Viewed by 3043 | Submission Open

Keywords: biomarker; genomic research; epigenomic research; molecular mechanisms; viral hepatitis; alcoholic-related liver disease; non-alcoholic fatty liver disease; autoimmune liver diseases; liver cirrhosis; hepatocellular carcinoma

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Integrated Approaches, Molecular Mechanism and Therapies in Ocular Surface Diseases

edited by

Caterina Gagliano

Marco Zeppieri

and

Mario Damiano Toro

submission deadline 20 Sep 2025 | 2 articles | Viewed by 3004 | Submission Open

Keywords: ocular surface diseases; dry eye; corneal ulcers; persistent epithelial defects; blood-derived products; blood-based therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Rheumatoid Arthritis: Molecular Mechanisms and Immunotherapy

edited by Irena Manolova

submission deadline 20 Sep 2025 | 2 articles | Viewed by 2999 | Submission Open

Keywords: rheumatoid arthritis; pathogenesis; innate immunity; adaptive immunity; inflammation; cytokines; autoantibodies; immunotherapy; clinical outcome

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Pathology, Diagnostics, and Therapeutics in Optic Neuropathies

edited by Tsz Kin Ng

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2980 | Submission Open

Keywords: optic neuropathies; glaucoma; optic nerve; retinal ganglion cells; neuroprotection; biomarkers; pathophysiology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Genetics, Breeding, and Multi-Omics Approaches in Rice Research

edited by

Zakaria Prodhan

submission deadline 20 Sep 2025 | 4 articles | Viewed by 2977 | Submission Open

Keywords: rice genetics and breeding; molecular breeding of rice; rice genomics and proteomics; genes related to abiotic stress tolerance in rice; molecular biology and multi-omics in rice research

(This special issue belongs to the Section Molecular Plant Sciences)

Adapter CAR T Cells: From the Idea to the Clinic

edited by

Michael P. Bachmann

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2963 | Submission Open

Keywords: CAR T cell therapy; chimeric antigen receptor; bispecific antibody; target module; autoimmune diseases; solid tumors

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Drug Discovery and Development Focusing on Natural Products

edited by

Chung-Hsin Wu

and

Szu-Chuan Shen

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2962 | Submission Open

Keywords: natural products; drug R& D; herbal medicine; gut microbiota; mechanism of action; therapeutic targets

(This special issue belongs to the Section Molecular Pharmacology)

Advancements in Host-Directed Antiviral Therapies

edited by

Raquel Bello-Morales

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2949 | Submission Open

Keywords: antiviral drugs; drug discovery; host cell targets; HIV; HCV; influenza; SARS-CoV-2

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Smooth Muscle Cells in Vascular Disease

edited by

Ida Daniela Perrotta

submission deadline 20 Sep 2025 | 3 articles | Viewed by 2942 | Submission Open

Keywords: smooth muscle cells (SMCs); atherosclerosis; hypertension; aortic aneurysm; vascular ageing; extracellular matrix; endothelial cells (ECs); SMC senescence; interleukin; platelet-derived growth factor; phenotype switching; SMC plasticity; SMC-derived cells; molecular subtypes; intimal thickening; plaque stability; transcription factors; microRNAs; clonality

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Strategies to Overcome Antibiotic Resistance in Carbapenem-Producing Bacteria

edited by

Daniela Calina

and

Ovidiu Zlatian

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2878 | Submission Open

Keywords: antibiotic resistance; antimicrobial agents; bacterial pathogens; carbapenemases; genomics; molecular mechanisms; therapeutic targets

(This special issue belongs to the Section Molecular Biology)

Heart Failure Risk Factors and Therapies on a Molecular Basis

edited by

Tomasz Urbanowicz

submission deadline 20 Sep 2025 | 2 articles | Viewed by 2875 | Submission Open

Keywords: heart failure; risk factors; inflammatory; neutrophils; cytokines; pharmacological; therapies; molecular-based processes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Current Trends in MOF (Metal–Organic Framework) and Metal X-ides Development, 2nd Edition

edited by Siwei Li

submission deadline 20 Sep 2025 | 2 articles | Viewed by 2856 | Submission Open

Keywords: MOF; metal carbide; metal sulfide; metal phosphide; catalysis; biomedicine; electromagnetic absorption; energy conversion and storage

(This special issue belongs to the Section Materials Science)

Tumor Microenvironment and Cancer Progression: Molecular Insights for Targeted Therapy

edited by

Tetiana Zaǐchuk

submission deadline 20 Sep 2025 | 3 articles | Viewed by 2826 | Submission Open

Keywords: tumor microenvironment; immune response modulation; signaling pathways; extracellular matrix components; tumor evolution

(This special issue belongs to the Section Molecular Oncology)

Application of Artificial Intelligence in Molecular Sciences

edited by

Jorge Mateo

submission deadline 20 Sep 2025 | 3 articles | Viewed by 2801 | Submission Open

Keywords: artificial intelligence; deep learning; algorithms; molecular modeling and simulation; materials discovery; analysis of biological sequence data; computational chemistry; bioinformatics; genomics; protein structure prediction; molecular dynamics simulation

(This special issue belongs to the Section Molecular Informatics)

The Impact of Mitochondria on Human Disease and Health

edited by

Martina Semenzato

submission deadline 20 Sep 2025 | 3 articles | Viewed by 2691 | Submission Open

Keywords: mitochondrial dysfunction; mitochondrial bioenergetics; mitochondrial dynamics; mitophagy; oxidative stress; mitochondrial DNA (mtDNA) mutations; neurodegenerative diseases; cardiovascular diseases; metabolic disorders; aging and mitochondria; cancer

(This special issue belongs to the Section Biochemistry)

Neuroinflammation in the Pathogenesis of Alzheimer’s Disease and Related Dementias: 2nd Edition

edited by

Amal Kaddoumi

submission deadline 20 Sep 2025 | 2 articles | Viewed by 2676 | Submission Open

Keywords: Alzheimer’ s disease; neuroinflammation; drug development; microglia; astrocytes; cytokines; TREM2; risk factors; biomarkers

(This special issue belongs to the Section Molecular Immunology)

The Roles of Mesenchymal Stem/Stromal Cells in Tumor Therapies

edited by Francesco Agostini

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2617 | Submission Open

Keywords: mesenchymal stem cells; tumor; cancer patients; ex vivo cell modification; cell and gene therapy; targeted drug delivery; homing; migration; current regulatory guidelines; MSC therapeutic potential

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Utilizing Induced Pluripotent Stem Cells and Cardiomyocytes: From Basic Research to Disease Modeling

edited by

Ofer Binah

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2614 | Submission Open

Keywords: induced pluripotent stem cells; cardiomyocytes; disease modeling; basic research; translational applications

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

False-Positive and False-Negative Laboratory Biomarkers

edited by Michela Salvatici and Lorenzo Drago

submission deadline 20 Sep 2025 | 2 articles | Viewed by 2602 | Submission Open

Keywords: biomarkers; false positives/negatives; protein biomarkers; nucleic acid markers; multi-omics; single-cell sequencing; liquid biopsy

(This special issue belongs to the Section Biochemistry)

Molecular Advances in Parvovirus

edited by Zahra Kadri

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2575 | Submission Open

Keywords: parvovirus structure; parvovirus replication; parvovirus proteome; cell signaling pathways; transcription; translation and post-translational modification; host restriction factor; host/parvovirus interaction; recombinant virus and VLP; immune evasion and/or activation; host tropism (cell type and species); new experimental models and approaches

(This special issue belongs to the Section Molecular Microbiology)

Emerging Heterocycles

edited by

David StC Black

and

Naresh Kumar

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2510 | Submission Open

Keywords: synthesis; reactions; applications; biological activity; medicinal chemistry; natural products; alkaloids; new methodology

(This special issue belongs to the Section Biochemistry)

The Molecular Role of Platelets in Human Diseases

edited by

Lukasz Szarpak

and

Michał Pruc

submission deadline 20 Sep 2025 | 3 articles | Viewed by 2505 | Submission Open

Keywords: platelet; biomarkers; platelet membrane proteins; platelet-derived microparticles; platelet-related diseases; thrombosis; inflammatory diseases; cardiovascular disease; cancer; tumor growth and metastasis

(This special issue belongs to the Section Molecular Biology)

The Gut-Brain Axis: Genomic and Metagenomic Involvement

edited by

Maria Gazouli

and Elias Odusseas Tzavellas

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2491 | Submission Open

Keywords: gut– brain axis; central nervous system; gastrointestinal tract; genomic; metagenomic

(This special issue belongs to the Section Molecular Neurobiology)

Microbiota’s Role in Respiratory Disorders and Diseases

edited by

Ioannis Alexandros Charitos

and Mauro Carone

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2479 | Submission Open

Keywords: microbiota; microbiome; metabolome; transcriptome; microbiota gut/lung axis; microbiota gut/oral axis; respiratory disorders; respiratory diseases; respiratory rehabilitation

(This special issue belongs to the Section Molecular Microbiology)

Novel Technologies in the Study of the Pathogenesis of Cardiac Diseases

edited by

Raffaella Lombardi

and

Suet Nee Chen

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2438 | Submission Open

Keywords: artificial Intelligence; multi-omics; organoids; engineered heart tissue; advanced imaging; personalized medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Antiphospholipid Syndrome: From Pathophysiology to Therapy

edited by

Cristina Belizna

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2374 | Submission Open

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Insights into Osteoclasts

edited by

David Gyori

submission deadline 20 Sep 2025 | 2 articles | Viewed by 2346 | Submission Open

Keywords: osteoclast; bone remodeling; osteoporosis; inflammatory arthritis; bone tumor

(This special issue belongs to the Section Molecular Biology)

Recent Advances and Challenges in Colorectal Cancer: From Molecular Research to Treatment

edited by

Premila Leiphrakpam

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2345 | Submission Open

Keywords: tumor biology; tumor heterogeneity; molecular mechanism involved in cancer initiation; progression; and metastasis; compensatory pathways; cancer screening; cancer biomarkers discovery; tumor molecular profiling methods; early cancer diagnosis; novel therapeutic strategies; targeted therapies; drug resistance

(This special issue belongs to the Section Molecular Oncology)

Molecular Insights into Role of Anthranilic Acid in Neuropsychiatric Diseases

edited by

Gregory F. Oxenkrug

submission deadline 20 Sep 2025 | 2 articles | Viewed by 2345 | Submission Open

Keywords: anthranilic acid; Alzheimer’ s disease; autism; schizophrenia; bipolar disorder; major depressive disorder; post-partum depression; COVID-19; interferons; attention deficit disorder; cognitive impairment; G-protein-coupled receptor 109A; microbiome; gut– brain axis

(This special issue belongs to the Section Molecular Neurobiology)

Editorial Board Members’ Collection Series: Cancer Metabolism

edited by

Giuseppe Lucarelli

Daniel W. Nixon

and

Gianfranco Peluso

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2340 | Submission Open

Keywords: cancer metabolism; metabolic pathway; glucose consumption and energy production; amino acid requirement

(This special issue belongs to the Section Molecular Oncology)

Molecular Dimensional Design, Synthesis Modification and Application of Sustainable Polymer Materials

edited by

Angelika Kmita

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2327 | Submission Open

Keywords: sustainable polymeric materials; 3D printing; sustainability; environmental impact; molecular modifications

(This special issue belongs to the Section Materials Science)

Blueprints of Enzymatic Function and Structure in Biocatalysis

edited by

Francesco Malatesta

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2315 | Submission Open

Keywords: enzyme; biocatalysis; enzyme structure; enzyme kinetics and thermodynamics; enzyme engineering; synthetic biology applications; sustainable biocatalyst design

(This special issue belongs to the Section Biochemistry)

Peptide Self-Assembly

edited by

Yi Jia

submission deadline 20 Sep 2025 | 3 articles | Viewed by 2293 | Submission Open

Keywords: peptide assembly; aromatic short peptides; bioinspired supramolecular architectures; functional materials; peptide microfabrication; anticancer therapy; supercapacitor; biosensing

(This special issue belongs to the Section Macromolecules)

Research of Hydroxyapatite-Based Materials and Their Applications

edited by

Daniela Predoi

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2288 | Submission Open

Keywords: hydroxyapatite; nanobiocomposite; biomedical applications; coatings; environment remediation; biological properties; drug delivery; pollutant adsorption efficiency; morphology and structural features

(This special issue belongs to the Section Materials Science)

Molecular Advances in Forensic Toxicology: Innovative Approaches in Detection of New Psychoactive Substances

edited by Roberta Tittarelli and Giulio Mannocchi

submission deadline 20 Sep 2025 | 2 articles | Viewed by 2236 | Submission Open

Keywords: addiction; new psychoactive substances; mass spectrometry; biological matrices; diversion; forensic toxicology; drug testing

(This special issue belongs to the Section Molecular Toxicology)

New Anti-cancer Agents: Design, Synthesis and Applications

edited by

Robert Czarnomysy

submission deadline 20 Sep 2025 | 2 articles | Viewed by 2230 | Submission Open

Keywords: anti-cancer drugs; cancer drug development; cancer therapy; rational drug design; structure– activity relationship; cancer therapeutics; cytotoxicity; apoptosis; anti-tumor activity

(This special issue belongs to the Section Molecular Pharmacology)

Fungal Pathogen-Host Interactions

edited by Patricia Albuquerque

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2218 | Submission Open

Keywords: medical mycology; host– microbe interactions; macrophages; dendritic cells; neutrophils

(This special issue belongs to the Section Molecular Microbiology)

Recent Research on Cardiac Troponins

edited by

Chiara Caselli

and

Rosetta Ragusa

submission deadline 20 Sep 2025 | 2 articles | Viewed by 2211 | Submission Open

Keywords: cardiac troponin; gene mutations; post-translational modifications; therapy; high-sensitivity (hs) immunoassays; mechanisms of release; biomarkers; cardiovascular disease

(This special issue belongs to the Section Molecular Biology)

Blood Cells in Human Health and Disease

edited by Leonid Livshits

submission deadline 20 Sep 2025 | 2 articles | Viewed by 2193 | Submission Open

Keywords: red blood cell; RBC membrane; RBC biophysical properties; RBC rheology; RBC mechanical properties; RBC membrane vesiculation; RBC clearance; RBC in diabetes; hemoglobinopathies; RBC storage TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Biochemistry)

Advances in Burn Wound Healing and Skin Regeneration: Innovations and Insights

edited by

H. Ibrahim Korkmaz

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2174 | Submission Open

Keywords: burn wound healing; skin regeneration; novel biomaterials; wound dressings; regenerative therapies

(This special issue belongs to the Section Biochemistry)

Characterization and Biological Function of Plant Extracts

edited by

Simonetta Cristina Di Simone

submission deadline 20 Sep 2025 | 2 articles | Viewed by 2129 | Submission Open

Keywords: plant extracts; phytochemical characterization; bioactive compounds; biological activity; molecular mechanisms; gene expression; pharmacognosy

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Advances in Olive and Its Derivatives

edited by

Fabrizio Carbone

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2121 | Submission Open

Keywords: olive; structural and functional genomics; genomic variation; breeding; biotechnologies; next-generation sequencing

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Insights into Flower Gene Regulation

edited by Wen‑Chieh Tsai

submission deadline 20 Sep 2025 | 2 articles | Viewed by 2102 | Submission Open

Keywords: floral gene regulation; flowers; homeotic genes; MADSBox; pollination

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Research on Oxidative Stress in Health and Disease

edited by

Amelia Maria Găman

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2087 | Submission Open

Keywords: oxidative stress; antioxidants; cancer; redox signalling; reactive oxygen and nitrogen species

(This special issue belongs to the Section Molecular Biology)

Recent Developments in Metabolism of Algal Toxins in Animals

edited by

Alexandre Campos

and

Pedro Reis Costa

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2067 | Submission Open

Keywords: marine toxins; bioacumulation; chemical conversion; detoxification mechanisms; toxin gene clusters

(This special issue belongs to the Section Molecular Toxicology)

Reproductive Genetics and Epigenetics: Insights into Infertility Failures and Treatment Pathways

edited by

Hossam H. Shawki

submission deadline 20 Sep 2025 | 3 articles | Viewed by 2049 | Submission Open

Keywords: infertility; epigenetics; polymorphism; gametogenesis; fertilization; embryo development; reproductive organs; congenital malformations

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Mechanisms and Treatment of Chronic Kidney Disease

edited by Xinming Chen

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2041 | Submission Open

Keywords: diabetes; cardiovascular diseases; nephrology; diabetic nephropathy

(This special issue belongs to the Section Molecular Biology)

Recent Advances in Retinal Neurobiology

edited by

Tamas Kovacs-Oller

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2030 | Submission Open

Keywords: retina; vision; disease; ganglion cells; amacrine cells; bipolar cells; horizontal cells; photoreceptors; astrocytes; microglia; Mü ller cells

(This special issue belongs to the Section Molecular Neurobiology)

Cellular Oxygen Homeostasis—3rd Edition

edited by

Verena Tretter

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2025 | Submission Open

Keywords: cellular oxygen homeostasis; redox signaling; cellular oxygen sensing; hypoxia; hyperoxia

(This special issue belongs to the Section Molecular Biology)

Displaying special issue 651-700 on page 14 of 68.

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