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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Lectins: Structural Diversity, Molecular Recognition and Emerging Applications

edited by

Patrícia Maria Guedes Paiva

submission deadline 20 Jun 2026 | Viewed by 235 | Submission Open

Keywords: lectins; structural diversity; molecular recognition; bioactivities; biomedical applications

(This special issue belongs to the Section Biochemistry)

Synthesis, Modification, and Functional Characterization of Advanced Biomaterials for Bone Tissue Engineering

edited by

Elisa Boanini

submission deadline 20 Jun 2026 | Viewed by 234 | Submission Open

Keywords: material functionalization; bioactive materials; antimicrobial; antibiofilm; coatings; scaffolds; bone cements; metal nanoparticles; controlled release; biocompatibility

(This special issue belongs to the Section Materials Science)

Molecular Horizons in Pain Therapeutics

edited by Alaa Abd-Elsayed

submission deadline 20 Jun 2026 | Viewed by 229 | Submission Open

Keywords: spinal cord stimulation; peripheral nerve stimulation; stem cell therapy; platelet-rich plasma (PRP) injections; chronic pain management; interventional pain procedure

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Antimicrobial Nanoparticles: Mechanisms, Applications, and Future Directions

edited by

Carmen Curutiu

and

Alina Maria Holban

submission deadline 20 Jun 2026 | Viewed by 227 | Submission Open

Keywords: antimicrobial activity; nanoparticles; biofilm nano-modulators; antibiotic resistence; wastewater treatment; preservative properties of nanoparticles

(This special issue belongs to the Section Molecular Microbiology)

Advanced Research on the Major Histocompatibility Complex (MHC): From Bench to Bedside

edited by Antonio Arnaiz-Villena

submission deadline 20 Jun 2026 | Viewed by 225 | Submission Open

Keywords: HLA; immunology; HLA genetics and pharmacogenetics; immune and other functions of the MHC; classical and nonclassical MHC class I HLA genes; HLA-G; HLA-E; HLA-F; MHC evolution; complement; autoimmunity; immunodeficiency; cancer; HIV

(This special issue belongs to the Section Molecular Immunology)

Genomics and Epigenetics of Stem Cell: An Update

edited by

Vikas Malik

submission deadline 20 Jun 2026 | Viewed by 223 | Submission Open

Keywords: stem cells; epigenetics; genomics; cell fate; self-renewal; differentiation; regenerative medicine; transcription factors

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Interplay Between Aging, Dementia and Renal Function: Mechanisms, Biomarkers and Therapeutic Targets

edited by

Luca Soraci

submission deadline 20 Jun 2026 | Viewed by 218 | Submission Open

Keywords: aging; dementia; neuroinflammation; kidney– brain axis; translational research; biomarkers; oxidative stress

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Design and Engineering of Carbon-Based Materials for Environmental Remediation and Bioenergy

edited by Hilda Elizabeth Reynel-Ávila

submission deadline 20 Jun 2026 | Viewed by 218 | Submission Open

Keywords: adsorption; catalysis; functionalization; molecular design; environmental; sustainable energy; tailoring

(This special issue belongs to the Section Materials Science)

Toxicology Research: Understanding and Predicting Compound—Induced Toxicity

edited by

Georgios Pampalakis

and

Eleni Zingkou

submission deadline 20 Jun 2026 | Viewed by 215 | Submission Open

Keywords: molecular toxicology; emerging toxicology; drug-induced toxicity; organ toxicology; animal models; in silico toxicology; in vitro models; pesticides; industrial chemicals

(This special issue belongs to the Section Molecular Toxicology)

New Insights into Environmental Stresses and Plants: Second Edition

edited by

Zhou Li

submission deadline 20 Jun 2026 | Viewed by 213 | Submission Open

Keywords: abiotic stress; biotic stress; adaptation; gene function; omics; metabolic regulation; stress signal; molecular mechanism

(This special issue belongs to the Section Molecular Plant Sciences)

Machine Learning in Disease Diagnosis and Treatment: 2nd Edition

edited by

Makrina Karaglani

submission deadline 20 Jun 2026 | Viewed by 212 | Submission Open

Keywords: machine learning; diagnosis; treatment; algorithm; predictive; artificial intelligence

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cell and Molecular Biology of Archaea

edited by

Federica De Lise

submission deadline 20 Jun 2026 | Viewed by 210 | Submission Open

Keywords: archaea; molecular biology; translation; gene expression regulation; biofilm; metabolism

(This special issue belongs to the Section Molecular Microbiology)

Sustainable Material Development Through Waste Utilization: From Molecular Insights to Functional Applications

edited by

Rosie Yagmur Yegin

submission deadline 20 Jun 2026 | Viewed by 210 | Submission Open

Keywords: sustainable materials; waste-derived materials; biodegradable polymers; green chemistry; functionalization; structure– property relationships; chemical modification; recycling; valorization; circular economy; composites; analytical techniques; industrial waste; agricultural waste

(This special issue belongs to the Section Materials Science)

Consensus-Based Approaches to Rational Drug Design and Predictive Toxicology

edited by

Fernando Daniel Prieto-Martínez

submission deadline 20 Jun 2026 | Viewed by 209 | Submission Open

Keywords: drug design; bioactive compounds; pharmacophore; molecular dynamics; protein– ligand interactions; activity cliffs; machine learning

(This special issue belongs to the Section Molecular Toxicology)

Graphene-based Nanocomposites

edited by

Oleksandr Ivasenko

submission deadline 20 Jun 2026 | Viewed by 206 | Submission Open

Keywords: graphite intercalates; graphene; reduced graphene oxide; grafting; vertical heterostructures; nanocomposites; covalent organic frameworks (COFs); 2D nanomaterials; biomimetic interfaces; interfacial engineering

(This special issue belongs to the Section Molecular Nanoscience)

Sphingolipids in Infections, Disorders and Diseases

edited by Elita Avota

submission deadline 20 Jun 2026 | Viewed by 205 | Submission Open

Keywords: sphingolipids; sphingolipid biosynthesis; sphingolipidoses; metabolic disorders; infections; lipidomics; sphingolipid targeting drugs

(This special issue belongs to the Section Biochemistry)

Infectious Diseases and Infection Models in Laboratory Animals

edited by

Hiraku Sasaki

and Fumio Ike

submission deadline 20 Jun 2026 | Viewed by 202 | Submission Open

Keywords: infection model; Infectious diseases in laboratory animals; bacterial infection; viral infection; parasitic infection; molecular diagnosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Natural Bioactive Compounds for Human Health, 3rd Edition

edited by

Hongjie Zhang

submission deadline 20 Jun 2026 | Viewed by 200 | Submission Open

Keywords: natural bioactive plant products; biological and pharmacological activity; natural plant drug discovery and development; nutraceuticals; botanical dietary supplement

(This special issue belongs to the Section Molecular Pharmacology)

Unraveling Bioactive Peptides: Structure, Function, and Applications

edited by

Sara Elsa Aita

submission deadline 20 Jun 2026 | Viewed by 199 | Submission Open

Keywords: bioactive peptides; peptide structure– activity relationship; peptidomics; bioactivity assays; human health

(This special issue belongs to the Section Macromolecules)

Surfactants: Design, Synthesis and Properties

edited by

Joanna Krawczyk

submission deadline 20 Jun 2026 | Viewed by 198 | Submission Open

Keywords: design and synthesis of surfactants; adsorption and aggregation properties of surfactants; behavior of surfactants at different interfaces; application of biosurfactants and specialist surfactants (industry; agriculture; medicine; pharmacy)

(This special issue belongs to the Section Materials Science)

Neuroinflammation: Emerging Insights and Advances in Drug Development

edited by

Guya Diletta Marconi

Francesca Diomede

Jacopo Pizzicannella

and Paolo Gugliemi

submission deadline 20 Jun 2026 | Viewed by 198 | Submission Open

Keywords: neuroinflammation; drugs; neurodegenerative; Parkinson’ s disease; Alzheimer’ s disease; multiple scleroris; stroke

(This special issue belongs to the Section Molecular Neurobiology)

Endometriosis: Current Trends and Research Developments

edited by

Sylvia Mechsner

and

Renata Voltolini Velho

submission deadline 20 Jun 2026 | Viewed by 198 | Submission Open

Keywords: endometriosis; molecular mechanisms; pathophysiology; hormonal regulation; immune response; epigenetics; inflammation; biomarkers; transcriptomics; therapeutic targets

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Mechanisms Associated with Exercise for Health and Performance

edited by Ciro José Brito

submission deadline 20 Jun 2026 | Viewed by 198 | Submission Open

Keywords: exercise science; sports medicine; aging; genetic and exercise; endocrinology; immunology

(This special issue belongs to the Section Molecular Biology)

Exploring Recent Research on Natural Compounds: From Biosynthesis to Application

edited by

Nitin Mantri

submission deadline 20 Jun 2026 | Viewed by 197 | Submission Open

Keywords: proteins like antibodies and enzymes; small molecules; plant extracts; biosynthesis; nanodelivery; drug discovery

(This special issue belongs to the Section Biochemistry)

Molecular Modeling in Pharmaceutical Sciences

edited by

Maciej Spiegel

submission deadline 20 Jun 2026 | Viewed by 191 | Submission Open

Keywords: molecular modeling; computer-aided drug design; molecular docking; drug discovery; quantum chemistry; molecular dynamics simulations; virtual screening; computational pharmacology; pharmacy; in silico methods

(This special issue belongs to the Section Molecular Pharmacology)

Precision Medicine for Cancer-Associated Thrombosis: The Role of Biomarkers

edited by Darko Antic

submission deadline 20 Jun 2026 | Viewed by 190 | Submission Open

Keywords: biomarkers; precision medicine; cancer-associated thrombosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Informatics and AI in Cancer Research

edited by

Nabil Adam

and

Robert Wieder

submission deadline 20 Jun 2026 | Viewed by 189 | Submission Open

Keywords: molecular informatics; artificial intelligence (AI); cancer research; personalized medicine; high-throughput data; biomarkers; clinical applications; longitudinal data

(This special issue belongs to the Section Molecular Informatics)

Advances in Tau Protein Research

edited by

Taxiarchis Katsinelos

submission deadline 20 Jun 2026 | Viewed by 188 | Submission Open

Keywords: tau biology; disease model systems; protein aggregation; tauopathies; neurodegeneration; Alzheimer’ s disase; seeded aggregation; amyloid filaments; tau propagation; antibodies; targeted protein degradation; tau therapeutics

(This special issue belongs to the Section Molecular Biology)

Combined and Mixture Exposure Toxicology of Cancer and Chronic Diseases

edited by

Alok Deoraj

and Quentin Felty

submission deadline 20 Jun 2026 | Viewed by 186 | Submission Open

Keywords: combined exposure; mixture exposure; toxicology of cancer; omics of cancer; AI in carcinogenesis; machine learning use in cancer; cancer biomarkers; pollutants of cancer; agrochemicals; endocrine-disruptive chemicals

(This special issue belongs to the Section Molecular Oncology)

Advanced Research on Antioxidant Activity

edited by Agnieszka Filipek

submission deadline 20 Jun 2026 | Viewed by 185 | Submission Open

Keywords: antioxidants; advanced mechanisms of action; signaling pathways; molecular mechanism; biologically active compounds

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Cellular Mechanisms of Pulmonary Arterial Hypertension

edited by

David P Marciano

and Saurabh Aggarwal

submission deadline 20 Jun 2026 | Viewed by 185 | Submission Open

Keywords: pulmonary arterial hypertension (PAH); pulmonary vascular remodeling; endothelial cells; endothelial dysfunction; smooth muscle cells; hyperplasia; pericytes; fibroblasts; monocytes; macrophage; neutrophil; mechanotransduction; oxidative stress; cytokines; extracellular vesicles; extracellular matrix; epigenetics; metabolism; biomarkers; therapeutics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Progress in Molecular Breeding and Genetic Engineering for Fruit Crop Improvement

edited by

Amelia Salimonti

submission deadline 20 Jun 2026 | Viewed by 184 | Submission Open

Keywords: genetics; GWAS; genome; abiotic and biotic stress; transcriptomic analysis; fruit crop germplasm; breeding

(This special issue belongs to the Section Molecular Plant Sciences)

Cellular Memory in Response to Environmental Conditions

edited by

Satoshi Kishigami

submission deadline 20 Jun 2026 | Viewed by 184 | Submission Open

Keywords: cellular memory; cellular environment; embryonic development; epigenetics; transgenerational inheritance; mammals; DOHaD

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms and Diagnostics in Hereditary Hemolytic Anemias

edited by Joan-Lluís Vives-Corrons

submission deadline 20 Jun 2026 | Viewed by 183 | Submission Open

Keywords: anemia; red blood cell erythropoiesis; membranopathies ; erythro enzymopathies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recombinant Proteins and Antibody Engineering for Diagnostic and Treatment of Emerging Infectious Diseases

edited by

Gustavo Helguera

submission deadline 20 Jun 2026 | 1 articles | Viewed by 175 | Submission Open

Keywords: recombinant proteins; antibody engineering; monoclonal antibodies; hemorrhagic fevers; tuberculosis; emerging infectious diseases; neglected viruses; diagnostics; therapeutic antibodies

(This special issue belongs to the Section Molecular Immunology)

Stress Signaling and Horticultural Crops Quality Control

edited by

Weibiao Liao

and

Yanjie Xie

submission deadline 20 Jun 2026 | Viewed by 174 | Submission Open

Keywords: stress tolerance; molecular mechanisms; quality traits; redox regulation; postharvest physiology; signal transduction

(This special issue belongs to the Section Molecular Plant Sciences)

Advanced Research in Alzheimer’s Disease: From Pathology to Therapy

edited by Sofía Yolanda Díaz Miranda

submission deadline 20 Jun 2026 | Viewed by 170 | Submission Open

Keywords: multifunctional compounds in Alzheimer’ s disease therapy; translational medicine in Alzheimer's disease; novel drug candidates for Alzheimer's disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Exploring Molecular Mechanisms of Prostate Cancer

edited by

Estefania Labanca

submission deadline 20 Jun 2026 | Viewed by 170 | Submission Open

Keywords: genetic alterations; signlaing pathways; cellular dysregulation; non-coding RNAs; epigenetics; tumor microenvironment; metabolic factors; therapuetic targeting; multi-modal approaches

(This special issue belongs to the Section Molecular Oncology)

Interstitial Lung Diseases: From Molecular Pathology to New Treatments

edited by

Yasuhiko Koga

submission deadline 20 Jun 2026 | Viewed by 169 | Submission Open

Keywords: interstitial lung diseases (ILDs); therapeutic strategies; molecular pathology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights into Skin Health and Disease

edited by Federica Li Pomi

submission deadline 20 Jun 2026 | Viewed by 168 | Submission Open

Keywords: dermatology; molecular mechanisms; targeted therapy; biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Biotic and Abiotic Stress Responses in Trees

edited by

Chenghao Li

submission deadline 20 Jun 2026 | Viewed by 167 | Submission Open

Keywords: drought stress; nutrient deficiency; salinity stress; pathogen defense; transcriptional regulation; epigenetic modifications; signal transduction; bioinformatics & multi-omics analysis; breeding for stress resilience

(This special issue belongs to the Section Molecular Plant Sciences)

New Trends in Green Synthesis of Nanomaterials

edited by Rocío Redón

submission deadline 20 Jun 2026 | Viewed by 163 | Submission Open

Keywords: nanoparticles; cytotoxicity; drug delivery; nanomaterials; green synthesis

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Research in Acute Lung Injury

edited by

Emilia Lecuona

submission deadline 20 Jun 2026 | Viewed by 161 | Submission Open

Keywords: acute lung injury; ARDS; primary graft dysfunction; immune cells; neutrophils; pulmonary edema; alveolar epithelium; lung endothelium

(This special issue belongs to the Section Molecular Immunology)

Recent Advances in Computer-Aided Drug Design

edited by

Cleber Melo-Filho

submission deadline 20 Jun 2026 | Viewed by 161 | Submission Open

Keywords: computer-aided drug design (CADD); quantitative structure-activity/property relationship (QSAR/QSPR); cheminformatics; virtual screening; data curation; in silico; molecular docking; machine learning; deep learning

(This special issue belongs to the Section Molecular Pharmacology)

Recent Advances in Genome-Edited Animal Models

edited by Takayuki Sakurai and

Masahiro Sato

submission deadline 20 Jun 2026 | Viewed by 160 | Submission Open

Keywords: genome editing; prime editing; base editing; CRISPRa/CRISPRi; knock-in/out; conditional genome editing; multiplex genome editing; manipulation of early embryos and germ cells; in vivo gene delivery; genome-edited animals; disease animal model

(This special issue belongs to the Section Molecular Genetics and Genomics)

New Perspectives in Protein Structure

edited by

Csaba Magyar

submission deadline 20 Jun 2026 | Viewed by 159 | Submission Open

Keywords: stability of protein complexes structural; background of protein function; allosteric regulation of proteins; fuzzy complexes; intrinsically disordered proteins; liquid-liquid phase separation; mutual synergistic folding; protein folding; protein structure; protein-protein interactions; transmembrane proteins

(This special issue belongs to the Section Molecular Biophysics)

Molecular Insights into Mechanobiology of Regeneration

edited by

Christopher Robinson

and Timothy R. Deer

submission deadline 20 Jun 2026 | Viewed by 159 | Submission Open

Keywords: mechanotransduction; regeneration; stem cells; extracellular matrix; tissue repair

(This special issue belongs to the Section Molecular Biophysics)

Neurobiology and Psychopharmacology of Mood Disorders

edited by

Luca Steardo

submission deadline 20 Jun 2026 | Viewed by 159 | Submission Open

Keywords: mood disorders; psychopharmacology; neurobiology; molecular mechanisms; biomarkers; translational psychiatry; neuroinflammation; signal transduction; animal models; epigenetics

(This special issue belongs to the Section Molecular Neurobiology)

Advances in the Genetics and Precision Breeding of Tomato

edited by Younghoon Park

submission deadline 20 Jun 2026 | Viewed by 158 | Submission Open

Keywords: climate change; gene editing; genomic selection; flavor; functional compounds; molecular marker; omics; precision breeding; Solanum lycopersicum; tomato

(This special issue belongs to the Section Molecular Plant Sciences)

Role of Microorganisms and Their Metabolites in Agriculture, Food and the Environment: 3rd Edition

edited by

Barbara Sokolowska

submission deadline 20 Jun 2026 | Viewed by 145 | Submission Open

Keywords: fermentation; biopreservation; biocontrol; biodegradation; bioremediation; bioaugmentation; omic-technologies

(This special issue belongs to the Section Molecular Microbiology)

Displaying special issue 3151-3200 on page 64 of 68.

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